Lobaria pulmonaria Switzerland extracted metagenome v1.0

Identified secondary metabolite regions using strictness 'relaxed'

scaffold_105

Region	Type	From	To	Most similar known cluster		Similarity
Region 58.1	T1PKS	25,160	93,716	oryzine A/oryzine B	Other	12%

scaffold_106

Region	Type	From	To	Most similar known cluster		Similarity
Region 69.1	fungal-RiPP-like	1	68,810

scaffold_1095

Region	Type	From	To	Most similar known cluster		Similarity
Region 108.1	T1PKS	1	9,915	4-oxomacrophorin A/macrophorin A/5'-epimacrophorin B	Terpene	18%

scaffold_110

Region	Type	From	To	Most similar known cluster		Similarity
Region 114.1	NRPS-like	1	44,462

scaffold_114

Region	Type	From	To	Most similar known cluster		Similarity
Region 158.1	T1PKS	1	61,170	monascorubrin	Polyketide	100%

scaffold_117

Region	Type	From	To	Most similar known cluster		Similarity
Region 191.1	T1PKS,NRPS	27,255	97,786	flavichalasine F/flavichalasine G/aspochalasin C/aspochalasin E/aspochalasin M/TMC-169/aspergillin PZ	Polyketide+NRP	54%

scaffold_118

Region	Type	From	To	Most similar known cluster		Similarity
Region 202.1	terpene	66,808	97,671

scaffold_121

Region	Type	From	To	Most similar known cluster		Similarity
Region 236.1	T1PKS	42,826	97,167

scaffold_126

Region	Type	From	To	Most similar known cluster		Similarity
Region 291.1	T1PKS,indole	1,218	66,773	cryptosporioptide B/cryptosporioptide A/cryptosporioptide C	Polyketide:Iterative type I polyketide	26%

scaffold_1285

Region	Type	From	To	Most similar known cluster		Similarity
Region 319.1	fungal-RiPP-like	1	4,476

scaffold_1336

Region	Type	From	To	Most similar known cluster		Similarity
Region 376.1	fungal-RiPP-like	1	3,108

scaffold_134

Region	Type	From	To	Most similar known cluster		Similarity
Region 380.1	fungal-RiPP-like	8,307	92,827

scaffold_1393

Region	Type	From	To	Most similar known cluster		Similarity
Region 439.1	fungal-RiPP-like	1	2,137

scaffold_14

Region	Type	From	To	Most similar known cluster		Similarity
Region 446.1	T1PKS	103,288	171,499	usnic acid	Polyketide	33%

scaffold_141

Region	Type	From	To	Most similar known cluster		Similarity
Region 454.1	indole	57,009	88,076

scaffold_150

Region	Type	From	To	Most similar known cluster		Similarity
Region 464.1	T1PKS	33,035	85,305

scaffold_157

Region	Type	From	To	Most similar known cluster		Similarity
Region 471.1	indole	20,736	51,991

scaffold_164

Region	Type	From	To	Most similar known cluster		Similarity
Region 479.1	T1PKS	41,114	82,269

scaffold_169

Region	Type	From	To	Most similar known cluster		Similarity
Region 484.1	T1PKS,NRPS	32,047	81,096

scaffold_18

Region	Type	From	To	Most similar known cluster		Similarity
Region 496.1	T1PKS	1	32,331

scaffold_185

Region	Type	From	To	Most similar known cluster		Similarity
Region 502.1	NRPS-like	17,121	77,591

scaffold_186

Region	Type	From	To	Most similar known cluster		Similarity
Region 503.1	fungal-RiPP-like	1	76,552

scaffold_188

Region	Type	From	To	Most similar known cluster		Similarity
Region 505.1	terpene	1	25,030

scaffold_19

Region	Type	From	To	Most similar known cluster		Similarity
Region 507.1	fungal-RiPP-like	1	59,164

scaffold_195

Region	Type	From	To	Most similar known cluster		Similarity
Region 513.1	T1PKS	1	60,390

scaffold_199

Region	Type	From	To	Most similar known cluster		Similarity
Region 517.1	fungal-RiPP-like	1	73,946

scaffold_207

Region	Type	From	To	Most similar known cluster		Similarity
Region 527.1	NRPS-like	3,589	67,586

scaffold_21

Region	Type	From	To	Most similar known cluster		Similarity
Region 530.1	fungal-RiPP-like	12,915	104,059

scaffold_210

Region	Type	From	To	Most similar known cluster		Similarity
Region 531.1	NRPS-like	1,263	64,615

scaffold_216

Region	Type	From	To	Most similar known cluster		Similarity
Region 537.1	fungal-RiPP-like	1	71,092

scaffold_224

Region	Type	From	To	Most similar known cluster		Similarity
Region 546.1	fungal-RiPP-like	1	65,582

scaffold_23

Region	Type	From	To	Most similar known cluster		Similarity
Region 552.1	NRPS-like	147,473	199,431

scaffold_230

Region	Type	From	To	Most similar known cluster		Similarity
Region 553.1	terpene	23,969	55,195

scaffold_260

Region	Type	From	To	Most similar known cluster		Similarity
Region 586.1	T1PKS	1	41,023	naphthopyrone	Polyketide	100%

scaffold_270

Region	Type	From	To	Most similar known cluster		Similarity
Region 597.1	T1PKS	1	35,313	patulin	Polyketide:Iterative type I polyketide	26%

scaffold_273

Region	Type	From	To	Most similar known cluster		Similarity
Region 600.1	NRPS	1	47,207	BII-rafflesfungin	NRP+Polyketide	15%

scaffold_276

Region	Type	From	To	Most similar known cluster		Similarity
Region 603.1	fungal-RiPP-like	1	59,975

scaffold_302

Region	Type	From	To	Most similar known cluster		Similarity
Region 633.1	NRPS	1	55,812

scaffold_306

Region	Type	From	To	Most similar known cluster		Similarity
Region 637.1	T1PKS	1	55,126

scaffold_307

Region	Type	From	To	Most similar known cluster		Similarity
Region 638.1	T1PKS	13,874	54,899

scaffold_309

Region	Type	From	To	Most similar known cluster		Similarity
Region 640.1	T1PKS	15,741	54,865	solanapyrone D	Polyketide	33%

scaffold_32

Region	Type	From	To	Most similar known cluster		Similarity
Region 652.1	NRPS-like	125,185	174,200

scaffold_321

Region	Type	From	To	Most similar known cluster		Similarity
Region 654.1	NRPS-like	1	37,896

scaffold_325

Region	Type	From	To	Most similar known cluster		Similarity
Region 658.1	indole	1	29,624

scaffold_327

Region	Type	From	To	Most similar known cluster		Similarity
Region 660.1	terpene	23,394	52,703

scaffold_345

Region	Type	From	To	Most similar known cluster		Similarity
Region 680.1	fungal-RiPP-like	1	50,859

scaffold_363

Region	Type	From	To	Most similar known cluster		Similarity
Region 700.1	fungal-RiPP-like	1	48,434

scaffold_365

Region	Type	From	To	Most similar known cluster		Similarity
Region 702.1	NRPS	1	48,247

scaffold_37

Region	Type	From	To	Most similar known cluster		Similarity
Region 707.1	fungal-RiPP-like	1,092	91,888	notoamide F/(+)-semivioxanthin/waikikiamide B/waikikiamide C/notoamide A/waikikiamide A	Polyketide	16%

scaffold_372

Region	Type	From	To	Most similar known cluster		Similarity
Region 710.1	fungal-RiPP-like	1	47,340

scaffold_386

Region	Type	From	To	Most similar known cluster		Similarity
Region 725.1	terpene	23,488	46,453

scaffold_404

Region	Type	From	To	Most similar known cluster		Similarity
Region 746.1	T1PKS,terpene	1	44,698

scaffold_41

Region	Type	From	To	Most similar known cluster		Similarity
Region 752.1	NRPS	1	77,465	fellutamide B	NRP	42%

scaffold_410

Region	Type	From	To	Most similar known cluster		Similarity
Region 753.1	terpene	23,245	43,963	squalestatin S1	Terpene	40%

scaffold_413

Region	Type	From	To	Most similar known cluster		Similarity
Region 756.1	terpene	3,460	35,652

scaffold_43

Region	Type	From	To	Most similar known cluster		Similarity
Region 774.1	terpene	114,732	145,388

scaffold_446

Region	Type	From	To	Most similar known cluster		Similarity
Region 792.1	fungal-RiPP-like	1	40,162

scaffold_456

Region	Type	From	To	Most similar known cluster		Similarity
Region 803.1	T1PKS	2,437	39,616

scaffold_474

Region	Type	From	To	Most similar known cluster		Similarity
Region 823.1	T1PKS	1	38,282	1,3,6,8-tetrahydroxynaphthalene	Polyketide	100%

scaffold_476

Region	Type	From	To	Most similar known cluster		Similarity
Region 825.1	T1PKS	1	38,166

scaffold_478

Region	Type	From	To	Most similar known cluster		Similarity
Region 827.1	T1PKS	1	37,891	eupenifeldin	Terpene	36%

scaffold_526

Region	Type	From	To	Most similar known cluster		Similarity
Region 881.1	T1PKS	1	34,474	1,3,6,8-tetrahydroxynaphthalene	Polyketide	100%

scaffold_53

Region	Type	From	To	Most similar known cluster		Similarity
Region 885.1	NRPS-like	98,316	135,428	aspulvinone H/aspulvinone B1	NRP	100%

scaffold_551

Region	Type	From	To	Most similar known cluster		Similarity
Region 909.1	terpene	1	27,217

scaffold_569

Region	Type	From	To	Most similar known cluster		Similarity
Region 928.1	T1PKS	1	31,556

scaffold_58

Region	Type	From	To	Most similar known cluster		Similarity
Region 940.1	T1PKS,NRPS	1	87,917	leucinostatin A/leucinostatin B	NRP+Polyketide	10%

scaffold_608

Region	Type	From	To	Most similar known cluster		Similarity
Region 972.1	NRPS-like	1	29,278

scaffold_64

Region	Type	From	To	Most similar known cluster		Similarity
Region 1007.1	fungal-RiPP-like	10,687	124,574

scaffold_650

Region	Type	From	To	Most similar known cluster		Similarity
Region 1019.1	fungal-RiPP-like	1	26,905

scaffold_661

Region	Type	From	To	Most similar known cluster		Similarity
Region 1031.1	NRP-metallophore,NRPS	1	26,542

scaffold_672

Region	Type	From	To	Most similar known cluster		Similarity
Region 1043.1	NRPS-like	1	25,650

scaffold_683

Region	Type	From	To	Most similar known cluster		Similarity
Region 1055.1	terpene	1	24,964

scaffold_690

Region	Type	From	To	Most similar known cluster		Similarity
Region 1063.1	fungal-RiPP-like	1	24,499

scaffold_70

Region	Type	From	To	Most similar known cluster		Similarity
Region 1074.1	T1PKS	54,435	121,653	ochratoxin A	NRP+Polyketide	100%

scaffold_701

Region	Type	From	To	Most similar known cluster		Similarity
Region 1076.1	T1PKS	1	23,894

scaffold_737

Region	Type	From	To	Most similar known cluster		Similarity
Region 1115.1	T1PKS	1	22,647

scaffold_746

Region	Type	From	To	Most similar known cluster		Similarity
Region 1125.1	NRPS	1	22,272

scaffold_753

Region	Type	From	To	Most similar known cluster		Similarity
Region 1133.1	terpene	1	16,862

scaffold_76

Region	Type	From	To	Most similar known cluster		Similarity
Region 1140.1	T1PKS	18,173	84,960	waikikiamide A/waikikiamide B/waikikiamide C/(+)-semivioxanthin/semivioxanthin	Polyketide	36%

scaffold_766

Region	Type	From	To	Most similar known cluster		Similarity
Region 1147.1	NRPS,indole	1	21,585

scaffold_767

Region	Type	From	To	Most similar known cluster		Similarity
Region 1148.1	terpene	1	16,783

scaffold_77

Region	Type	From	To	Most similar known cluster		Similarity
Region 1151.1	T1PKS,NRPS	60,152	116,591

scaffold_79

Region	Type	From	To	Most similar known cluster		Similarity
Region 1173.1	NRPS,T1PKS	48,645	115,605	pyranoviolin A	Polyketide+NRP	37%

scaffold_815

Region	Type	From	To	Most similar known cluster		Similarity
Region 1202.1	terpene	1	19,727

scaffold_82

Region	Type	From	To	Most similar known cluster		Similarity
Region 1207.1	T1PKS	29,308	97,607

scaffold_83

Region	Type	From	To	Most similar known cluster		Similarity
Region 1218.1	terpene	42,840	73,935

scaffold_904

Region	Type	From	To	Most similar known cluster		Similarity
Region 1301.1	T1PKS	1	16,139	betaenone A/betaenone B/betaenone C	Polyketide	25%

scaffold_92

Region	Type	From	To	Most similar known cluster		Similarity
Region 1318.1	NRPS-like	4,378	67,931

scaffold_933

Region	Type	From	To	Most similar known cluster		Similarity
Region 1333.1	NRPS	1	15,144

scaffold_945

Region	Type	From	To	Most similar known cluster		Similarity
Region 1346.1	T1PKS	1	14,461

scaffold_961

Region	Type	From	To	Most similar known cluster		Similarity
Region 1364.1	terpene	1	13,803

scaffold_97

Region	Type	From	To	Most similar known cluster		Similarity
Region 1373.1	NRPS-like	55,376	108,861

scaffold_973

Region	Type	From	To	Most similar known cluster		Similarity
Region 1377.1	T1PKS	1	13,354

No secondary metabolite regions were found in these records:: scaffold_1; scaffold_10; scaffold_100; scaffold_1000; scaffold_1001; scaffold_1002; scaffold_1003; scaffold_1004; scaffold_1005; scaffold_1006; scaffold_1007; scaffold_1008; scaffold_1009; scaffold_101; scaffold_1010; scaffold_1011; scaffold_1012; scaffold_1013; scaffold_1014; scaffold_1015; scaffold_1016; scaffold_1017; scaffold_1018; scaffold_1019; scaffold_102; scaffold_1020; scaffold_1021; scaffold_1022; scaffold_1023; scaffold_1024; scaffold_1025; scaffold_1026; scaffold_1027; scaffold_1028; scaffold_1029; scaffold_103; scaffold_1030; scaffold_1031; scaffold_1032; scaffold_1033; scaffold_1034; scaffold_1035; scaffold_1036; scaffold_1037; scaffold_1038; scaffold_1039; scaffold_104; scaffold_1040; scaffold_1041; scaffold_1042; scaffold_1043; scaffold_1044; scaffold_1045; scaffold_1046; scaffold_1047; scaffold_1048; scaffold_1049; scaffold_1050; scaffold_1051; scaffold_1052; scaffold_1053; scaffold_1054; scaffold_1055; scaffold_1056; scaffold_1057; scaffold_1058; scaffold_1059; scaffold_1060; scaffold_1061; scaffold_1062; scaffold_1063; scaffold_1064; scaffold_1065; scaffold_1066; scaffold_1067; scaffold_1068; scaffold_1069; scaffold_107; scaffold_1070; scaffold_1071; scaffold_1072; scaffold_1073; scaffold_1074; scaffold_1075; scaffold_1076; scaffold_1077; scaffold_1078; scaffold_1079; scaffold_108; scaffold_1080; scaffold_1081; scaffold_1082; scaffold_1083; scaffold_1084; scaffold_1085; scaffold_1086; scaffold_1087; scaffold_1088; scaffold_1089; scaffold_109; scaffold_1090; scaffold_1091; scaffold_1092; scaffold_1093; scaffold_1094; scaffold_1096; scaffold_1097; scaffold_1098; scaffold_1099; scaffold_11; scaffold_1100; scaffold_1101; scaffold_1102; scaffold_1103; scaffold_1104; scaffold_1105; scaffold_1106; scaffold_1107; scaffold_1108; scaffold_1109; scaffold_111; scaffold_1110; scaffold_1111; scaffold_1112; scaffold_1113; scaffold_1114; scaffold_1115; scaffold_1116; scaffold_1117; scaffold_1118; scaffold_1119; scaffold_112; scaffold_1120; scaffold_1121; scaffold_1122; scaffold_1123; scaffold_1124; scaffold_1125; scaffold_1126; scaffold_1127; scaffold_1128; scaffold_1129; scaffold_113; scaffold_1130; scaffold_1131; scaffold_1132; scaffold_1133; scaffold_1134; scaffold_1135; scaffold_1136; scaffold_1137; scaffold_1138; scaffold_1139; scaffold_1140; scaffold_1141; scaffold_1142; scaffold_1143; scaffold_1144; scaffold_1145; scaffold_1146; scaffold_1147; scaffold_1148; scaffold_1149; scaffold_115; scaffold_1150; scaffold_1151; scaffold_1152; scaffold_1153; scaffold_1154; scaffold_1155; scaffold_1156; scaffold_1157; scaffold_1158; scaffold_1159; scaffold_116; scaffold_1160; scaffold_1161; scaffold_1162; scaffold_1163; scaffold_1164; scaffold_1165; scaffold_1166; scaffold_1167; scaffold_1168; scaffold_1169; scaffold_1170; scaffold_1171; scaffold_1172; scaffold_1173; scaffold_1174; scaffold_1175; scaffold_1176; scaffold_1177; scaffold_1178; scaffold_1179; scaffold_1180; scaffold_1181; scaffold_1182; scaffold_1183; scaffold_1184; scaffold_1185; scaffold_1186; scaffold_1187; scaffold_1188; scaffold_1189; scaffold_119; scaffold_1190; scaffold_1191; scaffold_1192; scaffold_1193; scaffold_1194; scaffold_1195; scaffold_1196; scaffold_1197; scaffold_1198; scaffold_1199; scaffold_12; scaffold_120; scaffold_1200; scaffold_1201; scaffold_1202; scaffold_1203; scaffold_1204; scaffold_1205; scaffold_1206; scaffold_1207; scaffold_1208; scaffold_1209; scaffold_1210; scaffold_1211; scaffold_1212; scaffold_1213; scaffold_1214; scaffold_1215; scaffold_1216; scaffold_1217; scaffold_1218; scaffold_1219; scaffold_122; scaffold_1220; scaffold_1221; scaffold_1222; scaffold_1223; scaffold_1224; scaffold_1225; scaffold_1226; scaffold_1227; scaffold_1228; scaffold_1229; scaffold_123; scaffold_1230; scaffold_1231; scaffold_1232; scaffold_1233; scaffold_1234; scaffold_1235; scaffold_1236; scaffold_1237; scaffold_1238; scaffold_1239; scaffold_124; scaffold_1240; scaffold_1241; scaffold_1242; scaffold_1243; scaffold_1244; scaffold_1245; scaffold_1246; scaffold_1247; scaffold_1248; scaffold_1249; scaffold_125; scaffold_1250; scaffold_1251; scaffold_1252; scaffold_1253; scaffold_1254; scaffold_1255; scaffold_1256; scaffold_1257; scaffold_1258; scaffold_1259; scaffold_1260; scaffold_1261; scaffold_1262; scaffold_1263; scaffold_1264; scaffold_1265; scaffold_1266; scaffold_1267; scaffold_1268; scaffold_1269; scaffold_127; scaffold_1270; scaffold_1271; scaffold_1272; scaffold_1273; scaffold_1274; scaffold_1275; scaffold_1276; scaffold_1277; scaffold_1278; scaffold_1279; scaffold_128; scaffold_1280; scaffold_1281; scaffold_1282; scaffold_1283; scaffold_1284; scaffold_1286; scaffold_1287; scaffold_1288; scaffold_1289; scaffold_129; scaffold_1290; scaffold_1291; scaffold_1292; scaffold_1293; scaffold_1294; scaffold_1295; scaffold_1296; scaffold_1297; scaffold_1298; scaffold_1299; scaffold_13; scaffold_130; scaffold_1300; scaffold_1301; scaffold_1302; scaffold_1303; scaffold_1304; scaffold_1305; scaffold_1306; scaffold_1307; scaffold_1308; scaffold_1309; scaffold_131; scaffold_1310; scaffold_1311; scaffold_1312; scaffold_1313; scaffold_1314; scaffold_1315; scaffold_1316; scaffold_1317; scaffold_1318; scaffold_1319; scaffold_132; scaffold_1320; scaffold_1321; scaffold_1322; scaffold_1323; scaffold_1324; scaffold_1325; scaffold_1326; scaffold_1327; scaffold_1328; scaffold_1329; scaffold_133; scaffold_1330; scaffold_1331; scaffold_1332; scaffold_1333; scaffold_1334; scaffold_1335; scaffold_1337; scaffold_1338; scaffold_1339; scaffold_1340; scaffold_1341; scaffold_1342; scaffold_1343; scaffold_1344; scaffold_1345; scaffold_1346; scaffold_1347; scaffold_1348; scaffold_1349; scaffold_135; scaffold_1350; scaffold_1351; scaffold_1352; scaffold_1353; scaffold_1354; scaffold_1355; scaffold_1356; scaffold_1357; scaffold_1358; scaffold_1359; scaffold_136; scaffold_1360; scaffold_1361; scaffold_1362; scaffold_1363; scaffold_1364; scaffold_1365; scaffold_1366; scaffold_1367; scaffold_1368; scaffold_1369; scaffold_137; scaffold_1370; scaffold_1371; scaffold_1372; scaffold_1373; scaffold_1374; scaffold_1375; scaffold_1376; scaffold_1377; scaffold_1378; scaffold_1379; scaffold_138; scaffold_1380; scaffold_1381; scaffold_1382; scaffold_1383; scaffold_1384; scaffold_1385; scaffold_1386; scaffold_1387; scaffold_1388; scaffold_1389; scaffold_139; scaffold_1390; scaffold_1391; scaffold_1392; scaffold_1394; scaffold_1395; scaffold_1396; scaffold_1397; scaffold_1398; scaffold_1399; scaffold_140; scaffold_1400; scaffold_1401; scaffold_1402; scaffold_1403; scaffold_1404; scaffold_1405; scaffold_142; scaffold_143; scaffold_144; scaffold_145; scaffold_146; scaffold_147; scaffold_148; scaffold_149; scaffold_15; scaffold_151; scaffold_152; scaffold_153; scaffold_154; scaffold_155; scaffold_156; scaffold_158; scaffold_159; scaffold_16; scaffold_160; scaffold_161; scaffold_162; scaffold_163; scaffold_165; scaffold_166; scaffold_167; scaffold_168; scaffold_17; scaffold_170; scaffold_171; scaffold_172; scaffold_173; scaffold_174; scaffold_175; scaffold_176; scaffold_177; scaffold_178; scaffold_179; scaffold_180; scaffold_181; scaffold_182; scaffold_183; scaffold_184; scaffold_187; scaffold_189; scaffold_190; scaffold_191; scaffold_192; scaffold_193; scaffold_194; scaffold_196; scaffold_197; scaffold_198; scaffold_2; scaffold_20; scaffold_200; scaffold_201; scaffold_202; scaffold_203; scaffold_204; scaffold_205; scaffold_206; scaffold_208; scaffold_209; scaffold_211; scaffold_212; scaffold_213; scaffold_214; scaffold_215; scaffold_217; scaffold_218; scaffold_219; scaffold_22; scaffold_220; scaffold_221; scaffold_222; scaffold_223; scaffold_225; scaffold_226; scaffold_227; scaffold_228; scaffold_229; scaffold_231; scaffold_232; scaffold_233; scaffold_234; scaffold_235; scaffold_236; scaffold_237; scaffold_238; scaffold_239; scaffold_24; scaffold_240; scaffold_241; scaffold_242; scaffold_243; scaffold_244; scaffold_245; scaffold_246; scaffold_247; scaffold_248; scaffold_249; scaffold_25; scaffold_250; scaffold_251; scaffold_252; scaffold_253; scaffold_254; scaffold_255; scaffold_256; scaffold_257; scaffold_258; scaffold_259; scaffold_26; scaffold_261; scaffold_262; scaffold_263; scaffold_264; scaffold_265; scaffold_266; scaffold_267; scaffold_268; scaffold_269; scaffold_27; scaffold_271; scaffold_272; scaffold_274; scaffold_275; scaffold_277; scaffold_278; scaffold_279; scaffold_28; scaffold_280; scaffold_281; scaffold_282; scaffold_283; scaffold_284; scaffold_285; scaffold_286; scaffold_287; scaffold_288; scaffold_289; scaffold_29; scaffold_290; scaffold_291; scaffold_292; scaffold_293; scaffold_294; scaffold_295; scaffold_296; scaffold_297; scaffold_298; scaffold_299; scaffold_3; scaffold_30; scaffold_300; scaffold_301; scaffold_303; scaffold_304; scaffold_305; scaffold_308; scaffold_31; scaffold_310; scaffold_311; scaffold_312; scaffold_313; scaffold_314; scaffold_315; scaffold_316; scaffold_317; scaffold_318; scaffold_319; scaffold_320; scaffold_322; scaffold_323; scaffold_324; scaffold_326; scaffold_328; scaffold_329; scaffold_33; scaffold_330; scaffold_331; scaffold_332; scaffold_333; scaffold_334; scaffold_335; scaffold_336; scaffold_337; scaffold_338; scaffold_339; scaffold_34; scaffold_340; scaffold_341; scaffold_342; scaffold_343; scaffold_344; scaffold_346; scaffold_347; scaffold_348; scaffold_349; scaffold_35; scaffold_350; scaffold_351; scaffold_352; scaffold_353; scaffold_354; scaffold_355; scaffold_356; scaffold_357; scaffold_358; scaffold_359; scaffold_36; scaffold_360; scaffold_361; scaffold_362; scaffold_364; scaffold_366; scaffold_367; scaffold_368; scaffold_369; scaffold_370; scaffold_371; scaffold_373; scaffold_374; scaffold_375; scaffold_376; scaffold_377; scaffold_378; scaffold_379; scaffold_38; scaffold_380; scaffold_381; scaffold_382; scaffold_383; scaffold_384; scaffold_385; scaffold_387; scaffold_388; scaffold_389; scaffold_39; scaffold_390; scaffold_391; scaffold_392; scaffold_393; scaffold_394; scaffold_395; scaffold_396; scaffold_397; scaffold_398; scaffold_399; scaffold_4; scaffold_40; scaffold_400; scaffold_401; scaffold_402; scaffold_403; scaffold_405; scaffold_406; scaffold_407; scaffold_408; scaffold_409; scaffold_411; scaffold_412; scaffold_414; scaffold_415; scaffold_416; scaffold_417; scaffold_418; scaffold_419; scaffold_42; scaffold_420; scaffold_421; scaffold_422; scaffold_423; scaffold_424; scaffold_425; scaffold_426; scaffold_427; scaffold_428; scaffold_429; scaffold_430; scaffold_431; scaffold_432; scaffold_433; scaffold_434; scaffold_435; scaffold_436; scaffold_437; scaffold_438; scaffold_439; scaffold_44; scaffold_440; scaffold_441; scaffold_442; scaffold_443; scaffold_444; scaffold_445; scaffold_447; scaffold_448; scaffold_449; scaffold_45; scaffold_450; scaffold_451; scaffold_452; scaffold_453; scaffold_454; scaffold_455; scaffold_457; scaffold_458; scaffold_459; scaffold_46; scaffold_460; scaffold_461; scaffold_462; scaffold_463; scaffold_464; scaffold_465; scaffold_466; scaffold_467; scaffold_468; scaffold_469; scaffold_47; scaffold_470; scaffold_471; scaffold_472; scaffold_473; scaffold_475; scaffold_477; scaffold_479; scaffold_48; scaffold_480; scaffold_481; scaffold_482; scaffold_483; scaffold_484; scaffold_485; scaffold_486; scaffold_487; scaffold_488; scaffold_489; scaffold_49; scaffold_490; scaffold_491; scaffold_492; scaffold_493; scaffold_494; scaffold_495; scaffold_496; scaffold_497; scaffold_498; scaffold_499; scaffold_5; scaffold_50; scaffold_500; scaffold_501; scaffold_502; scaffold_503; scaffold_504; scaffold_505; scaffold_506; scaffold_507; scaffold_508; scaffold_509; scaffold_51; scaffold_510; scaffold_511; scaffold_512; scaffold_513; scaffold_514; scaffold_515; scaffold_516; scaffold_517; scaffold_518; scaffold_519; scaffold_52; scaffold_520; scaffold_521; scaffold_522; scaffold_523; scaffold_524; scaffold_525; scaffold_527; scaffold_528; scaffold_529; scaffold_530; scaffold_531; scaffold_532; scaffold_533; scaffold_534; scaffold_535; scaffold_536; scaffold_537; scaffold_538; scaffold_539; scaffold_54; scaffold_540; scaffold_541; scaffold_542; scaffold_543; scaffold_544; scaffold_545; scaffold_546; scaffold_547; scaffold_548; scaffold_549; scaffold_55; scaffold_550; scaffold_552; scaffold_553; scaffold_554; scaffold_555; scaffold_556; scaffold_557; scaffold_558; scaffold_559; scaffold_56; scaffold_560; scaffold_561; scaffold_562; scaffold_563; scaffold_564; scaffold_565; scaffold_566; scaffold_567; scaffold_568; scaffold_57; scaffold_570; scaffold_571; scaffold_572; scaffold_573; scaffold_574; scaffold_575; scaffold_576; scaffold_577; scaffold_578; scaffold_579; scaffold_580; scaffold_581; scaffold_582; scaffold_583; scaffold_584; scaffold_585; scaffold_586; scaffold_587; scaffold_588; scaffold_589; scaffold_59; scaffold_590; scaffold_591; scaffold_592; scaffold_593; scaffold_594; scaffold_595; scaffold_596; scaffold_597; scaffold_598; scaffold_599; scaffold_6; scaffold_60; scaffold_600; scaffold_601; scaffold_602; scaffold_603; scaffold_604; scaffold_605; scaffold_606; scaffold_607; scaffold_609; scaffold_61; scaffold_610; scaffold_611; scaffold_612; scaffold_613; scaffold_614; scaffold_615; scaffold_616; scaffold_617; scaffold_618; scaffold_619; scaffold_62; scaffold_620; scaffold_621; scaffold_622; scaffold_623; scaffold_624; scaffold_625; scaffold_626; scaffold_627; scaffold_628; scaffold_629; scaffold_63; scaffold_630; scaffold_631; scaffold_632; scaffold_633; scaffold_634; scaffold_635; scaffold_636; scaffold_637; scaffold_638; scaffold_639; scaffold_640; scaffold_641; scaffold_642; scaffold_643; scaffold_644; scaffold_645; scaffold_646; scaffold_647; scaffold_648; scaffold_649; scaffold_65; scaffold_651; scaffold_652; scaffold_653; scaffold_654; scaffold_655; scaffold_656; scaffold_657; scaffold_658; scaffold_659; scaffold_66; scaffold_660; scaffold_662; scaffold_663; scaffold_664; scaffold_665; scaffold_666; scaffold_667; scaffold_668; scaffold_669; scaffold_67; scaffold_670; scaffold_671; scaffold_673; scaffold_674; scaffold_675; scaffold_676; scaffold_677; scaffold_678; scaffold_679; scaffold_68; scaffold_680; scaffold_681; scaffold_682; scaffold_684; scaffold_685; scaffold_686; scaffold_687; scaffold_688; scaffold_689; scaffold_69; scaffold_691; scaffold_692; scaffold_693; scaffold_694; scaffold_695; scaffold_696; scaffold_697; scaffold_698; scaffold_699; scaffold_7; scaffold_700; scaffold_702; scaffold_703; scaffold_704; scaffold_705; scaffold_706; scaffold_707; scaffold_708; scaffold_709; scaffold_71; scaffold_710; scaffold_711; scaffold_712; scaffold_713; scaffold_714; scaffold_715; scaffold_716; scaffold_717; scaffold_718; scaffold_719; scaffold_72; scaffold_720; scaffold_721; scaffold_722; scaffold_723; scaffold_724; scaffold_725; scaffold_726; scaffold_727; scaffold_728; scaffold_729; scaffold_73; scaffold_730; scaffold_731; scaffold_732; scaffold_733; scaffold_734; scaffold_735; scaffold_736; scaffold_738; scaffold_739; scaffold_74; scaffold_740; scaffold_741; scaffold_742; scaffold_743; scaffold_744; scaffold_745; scaffold_747; scaffold_748; scaffold_749; scaffold_75; scaffold_750; scaffold_751; scaffold_752; scaffold_754; scaffold_755; scaffold_756; scaffold_757; scaffold_758; scaffold_759; scaffold_760; scaffold_761; scaffold_762; scaffold_763; scaffold_764; scaffold_765; scaffold_768; scaffold_769; scaffold_770; scaffold_771; scaffold_772; scaffold_773; scaffold_774; scaffold_775; scaffold_776; scaffold_777; scaffold_778; scaffold_779; scaffold_78; scaffold_780; scaffold_781; scaffold_782; scaffold_783; scaffold_784; scaffold_785; scaffold_786; scaffold_787; scaffold_788; scaffold_789; scaffold_790; scaffold_791; scaffold_792; scaffold_793; scaffold_794; scaffold_795; scaffold_796; scaffold_797; scaffold_798; scaffold_799; scaffold_8; scaffold_80; scaffold_800; scaffold_801; scaffold_802; scaffold_803; scaffold_804; scaffold_805; scaffold_806; scaffold_807; scaffold_808; scaffold_809; scaffold_81; scaffold_810; scaffold_811; scaffold_812; scaffold_813; scaffold_814; scaffold_816; scaffold_817; scaffold_818; scaffold_819; scaffold_820; scaffold_821; scaffold_822; scaffold_823; scaffold_824; scaffold_825; scaffold_826; scaffold_827; scaffold_828; scaffold_829; scaffold_830; scaffold_831; scaffold_832; scaffold_833; scaffold_834; scaffold_835; scaffold_836; scaffold_837; scaffold_838; scaffold_839; scaffold_84; scaffold_840; scaffold_841; scaffold_842; scaffold_843; scaffold_844; scaffold_845; scaffold_846; scaffold_847; scaffold_848; scaffold_849; scaffold_85; scaffold_850; scaffold_851; scaffold_852; scaffold_853; scaffold_854; scaffold_855; scaffold_856; scaffold_857; scaffold_858; scaffold_859; scaffold_86; scaffold_860; scaffold_861; scaffold_862; scaffold_863; scaffold_864; scaffold_865; scaffold_866; scaffold_867; scaffold_868; scaffold_869; scaffold_87; scaffold_870; scaffold_871; scaffold_872; scaffold_873; scaffold_874; scaffold_875; scaffold_876; scaffold_877; scaffold_878; scaffold_879; scaffold_88; scaffold_880; scaffold_881; scaffold_882; scaffold_883; scaffold_884; scaffold_885; scaffold_886; scaffold_887; scaffold_888; scaffold_889; scaffold_89; scaffold_890; scaffold_891; scaffold_892; scaffold_893; scaffold_894; scaffold_895; scaffold_896; scaffold_897; scaffold_898; scaffold_899; scaffold_9; scaffold_90; scaffold_900; scaffold_901; scaffold_902; scaffold_903; scaffold_905; scaffold_906; scaffold_907; scaffold_908; scaffold_909; scaffold_91; scaffold_910; scaffold_911; scaffold_912; scaffold_913; scaffold_914; scaffold_915; scaffold_916; scaffold_917; scaffold_918; scaffold_919; scaffold_920; scaffold_921; scaffold_922; scaffold_923; scaffold_924; scaffold_925; scaffold_926; scaffold_927; scaffold_928; scaffold_929; scaffold_93; scaffold_930; scaffold_931; scaffold_932; scaffold_934; scaffold_935; scaffold_936; scaffold_937; scaffold_938; scaffold_939; scaffold_94; scaffold_940; scaffold_941; scaffold_942; scaffold_943; scaffold_944; scaffold_946; scaffold_947; scaffold_948; scaffold_949; scaffold_95; scaffold_950; scaffold_951; scaffold_952; scaffold_953; scaffold_954; scaffold_955; scaffold_956; scaffold_957; scaffold_958; scaffold_959; scaffold_96; scaffold_960; scaffold_962; scaffold_963; scaffold_964; scaffold_965; scaffold_966; scaffold_967; scaffold_968; scaffold_969; scaffold_970; scaffold_971; scaffold_972; scaffold_974; scaffold_975; scaffold_976; scaffold_977; scaffold_978; scaffold_979; scaffold_98; scaffold_980; scaffold_981; scaffold_982; scaffold_983; scaffold_984; scaffold_985; scaffold_986; scaffold_987; scaffold_988; scaffold_989; scaffold_99; scaffold_990; scaffold_991; scaffold_992; scaffold_993; scaffold_994; scaffold_995; scaffold_996; scaffold_997; scaffold_998; scaffold_999

Compact view

scaffold_105 - Region 1 - T1PKS

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Location: 25,160 - 93,716 nt. (total: 68,557 nt) Show pHMM detection rules used

T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))

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core biosynthetic genes

additional biosynthetic genes

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NRPS/PKS domains

KnownClusterBlast

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Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

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NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 1, location 25159 - 93716:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (pk)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

4281029

PKS_AT (580..905): pk

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 79.2%; Methylmalonyl-CoA: 75.0%; Ethylmalonyl-CoA: 66.7%

minowa: Methylmalonyl-CoA

Prediction, score:

Methylmalonyl-CoA: 64.5
Methoxymalonyl-CoA: 62.2
Malonyl-CoA: 55.5
Ethylmalonyl-CoA: 36.9
Isobutyryl-CoA: 33.8
Propionyl-CoA: 32.2
inactive: 26.0
fatty_acid: 20.7
Benzoyl-CoA: 18.7
Acetyl-CoA: 15.0
CHC-CoA: 11.2
2-Methylbutyryl-CoA: 8.8
trans-1,2-CPDA: 8.0
3-Methylbutyryl-CoA: -2.9

scaffold_106 - Region 1 - fungal-RiPP-like

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Location: 1 - 68,810 nt. (total: 68,810 nt) Show pHMM detection rules used

Region on contig edge.

fungal-RiPP-like: DUF3328

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core biosynthetic genes

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No matches found.

scaffold_1095 - Region 1 - T1PKS

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Location: 1 - 9,915 nt. (total: 9,915 nt) Show pHMM detection rules used

Region on contig edge.

T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

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other genes

resistance

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NRPS/PKS domains

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Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

Detailed domain annotation

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NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 1, location 0 - 9915:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (pk)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

160771

PKS_AT (580..873): pk

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 83.3%; Methylmalonyl-CoA: 70.8%; Ethylmalonyl-CoA: 66.7%

minowa: Methylmalonyl-CoA

Prediction, score:

Methylmalonyl-CoA: 113.5
Ethylmalonyl-CoA: 91.6
Methoxymalonyl-CoA: 89.9
Malonyl-CoA: 66.5
Isobutyryl-CoA: 64.8
Propionyl-CoA: 38.1
2-Methylbutyryl-CoA: 36.6
Acetyl-CoA: 33.2
trans-1,2-CPDA: 31.8
fatty_acid: 25.2
CHC-CoA: 21.2
Benzoyl-CoA: 20.6
3-Methylbutyryl-CoA: 11.6
inactive: 0.0

scaffold_110 - Region 1 - NRPS-like

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Location: 1 - 44,462 nt. (total: 44,462 nt) Show pHMM detection rules used

Region on contig edge.

NRPS-like: cds((PP-binding or NAD_binding_4) and (AMP-binding or A-OX))

Legend:

core biosynthetic genes

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resistance

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Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

Detailed domain annotation

Selected features only

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No matches found.

Module view

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NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 1, location 0 - 44462:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (X)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

4176233

AMP-binding (55..357): X

nrpys: (unknown)

SVM prediction details:

NOTE: uncertain match

Predicted physicochemical class:: N/A
Large clusters prediction:: Aliphatic chain with H-bond donor (Asp, Asn, Glu, Gln, Aad)
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: ---YLGM--K
Nearest Stachelhaus code(s):
Stachelhaus code match:: 0% (weak)

scaffold_114 - Region 1 - T1PKS

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Location: 1 - 61,170 nt. (total: 61,170 nt) Show pHMM detection rules used

Region on contig edge.

T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

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NRPS/PKS domains

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Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

Detailed domain annotation

Selected features only

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Similar known gene clusters from MIBiG 3.1

Module view

Legend

NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 1, location 0 - 61170:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (pk)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

4268922

PKS_AT (925..1218): pk

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 62.5%; Ethylmalonyl-CoA: 58.3%; Methylmalonyl-CoA: 58.3%

minowa: Methoxymalonyl-CoA

Prediction, score:

Methoxymalonyl-CoA: 54.1
inactive: 53.6
Methylmalonyl-CoA: 46.1
Malonyl-CoA: 36.8
Propionyl-CoA: 28.5
CHC-CoA: 26.5
Ethylmalonyl-CoA: 22.7
2-Methylbutyryl-CoA: 18.9
fatty_acid: 18.1
trans-1,2-CPDA: 17.9
Acetyl-CoA: 17.8
Benzoyl-CoA: 15.4
3-Methylbutyryl-CoA: 14.1
Isobutyryl-CoA: 12.8

scaffold_117 - Region 1 - NRPS,T1PKS

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Location: 27,255 - 97,786 nt. (total: 70,532 nt) Show pHMM detection rules used

Region on contig edge.

T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))
NRPS: cds(Condensation and (AMP-binding or A-OX))

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

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NRPS/PKS domains

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Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

Detailed domain annotation

Selected features only

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Similar known gene clusters from MIBiG 3.1

Module view

Legend

NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 1, location 27254 - 97786:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (pk) + (pk - X)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

4016945

PKS_AT (536..838): pk

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 75.0%; Methylmalonyl-CoA: 62.5%; Propionyl-CoA: 58.3%

minowa: Methylmalonyl-CoA

Prediction, score:

Methylmalonyl-CoA: 90.2
Methoxymalonyl-CoA: 70.4
Isobutyryl-CoA: 62.4
Ethylmalonyl-CoA: 57.8
Propionyl-CoA: 45.1
Malonyl-CoA: 45.1
Benzoyl-CoA: 31.1
2-Methylbutyryl-CoA: 28.0
trans-1,2-CPDA: 21.8
fatty_acid: 20.8
Acetyl-CoA: 16.8
CHC-CoA: 14.6
3-Methylbutyryl-CoA: 14.6
inactive: 0.0

276554

PKS_AT (562..877): pk

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 79.2%; Methylmalonyl-CoA: 66.7%; Methoxymalonyl-CoA: 58.3%

minowa: Methylmalonyl-CoA

Prediction, score:

Methylmalonyl-CoA: 73.0
Methoxymalonyl-CoA: 64.7
Ethylmalonyl-CoA: 51.7
Malonyl-CoA: 35.8
Propionyl-CoA: 27.9
Isobutyryl-CoA: 27.4
Benzoyl-CoA: 24.9
3-Methylbutyryl-CoA: 22.0
2-Methylbutyryl-CoA: 21.6
trans-1,2-CPDA: 16.2
fatty_acid: 15.3
inactive: 13.5
CHC-CoA: 10.1
Acetyl-CoA: 9.1

AMP-binding (3070..3474): X

nrpys: Orn, Lys, Arg

SVM prediction details:

Predicted physicochemical class:: N/A
Large clusters prediction:: Long positively charged side chain (Orn, Lys, Arg)
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: DMAGLGCLCK
Nearest Stachelhaus code(s):: Hpg DAAHLGLLCK (50% 8� match)
Stachelhaus code match:: 70% (weak)

scaffold_118 - Region 1 - terpene

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Location: 66,808 - 97,671 nt. (total: 30,864 nt) Show pHMM detection rules used

Region on contig edge.

terpene: (Terpene_synth or Terpene_synth_C or phytoene_synt or Lycopene_cycl or terpene_cyclase or NapT7 or fung_ggpps or fung_ggpps2 or trichodiene_synth or TRI5)

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

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resistance

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Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

Similar known gene clusters from MIBiG 3.1

No matches found.

scaffold_121 - Region 1 - T1PKS

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Location: 42,826 - 97,167 nt. (total: 54,342 nt) Show pHMM detection rules used

Region on contig edge.

T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

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NRPS/PKS domains

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Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

Detailed domain annotation

Selected features only

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Similar known gene clusters from MIBiG 3.1

No matches found.

Module view

Legend

NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 1, location 42825 - 97167:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (pk)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

4191479

PKS_AT (597..919): pk

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 75.0%; Methylmalonyl-CoA: 62.5%; Propionyl-CoA: 58.3%

minowa: Methoxymalonyl-CoA

Prediction, score:

Methoxymalonyl-CoA: 83.5
Methylmalonyl-CoA: 80.3
Malonyl-CoA: 77.4
Isobutyryl-CoA: 49.1
Ethylmalonyl-CoA: 40.9
Propionyl-CoA: 31.6
3-Methylbutyryl-CoA: 30.8
Benzoyl-CoA: 26.2
inactive: 25.6
trans-1,2-CPDA: 23.4
fatty_acid: 17.9
CHC-CoA: 13.0
Acetyl-CoA: 12.2
2-Methylbutyryl-CoA: 5.7

scaffold_126 - Region 1 - T1PKS,indole

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Location: 1,218 - 66,773 nt. (total: 65,556 nt) Show pHMM detection rules used

T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))
indole: (indsynth or dmat or indole_PTase)

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

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Gene overview

NRPS/PKS domains

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Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

Detailed domain annotation

Selected features only

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Similar known gene clusters from MIBiG 3.1

Module view

Legend

NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 1, location 1217 - 66773:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (mal)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

4192224

PKS_AT (924..1222): mal

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 75.0%; inactive: 62.5%; Methylmalonyl-CoA: 54.2%

minowa: Malonyl-CoA

Prediction, score:

Malonyl-CoA: 101.2
inactive: 77.1
Methylmalonyl-CoA: 58.9
Methoxymalonyl-CoA: 48.3
Propionyl-CoA: 41.3
Benzoyl-CoA: 22.3
fatty_acid: 21.7
2-Methylbutyryl-CoA: 20.7
Isobutyryl-CoA: 18.6
CHC-CoA: 18.4
Ethylmalonyl-CoA: 17.8
trans-1,2-CPDA: 15.1
Acetyl-CoA: 12.0
3-Methylbutyryl-CoA: 9.2

4060478

AMP-binding (153..561): X

nrpys: Phe, Trp, Ph-Gly, Tyr, bOH-Tyr

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aromatic (Phe, Tyr, diOH-Bz, Ph-Gly, bOH-Tyr)
Large clusters prediction:: Aromatic side chain (Phe, Trp, Ph-Gly, Tyr, bOH-Tyr)
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: --AVQGNGSK
Nearest Stachelhaus code(s):
Stachelhaus code match:: 0% (weak)

scaffold_1285 - Region 1 - fungal-RiPP-like

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Location: 1 - 4,476 nt. (total: 4,476 nt) Show pHMM detection rules used

Region on contig edge.

fungal-RiPP-like: DUF3328

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scaffold_1336 - Region 1 - fungal-RiPP-like

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Location: 1 - 3,108 nt. (total: 3,108 nt) Show pHMM detection rules used

Region on contig edge.

fungal-RiPP-like: DUF3328

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scaffold_134 - Region 1 - fungal-RiPP-like

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Location: 8,307 - 92,827 nt. (total: 84,521 nt) Show pHMM detection rules used

Region on contig edge.

fungal-RiPP-like: DUF3328

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scaffold_1393 - Region 1 - fungal-RiPP-like

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Location: 1 - 2,137 nt. (total: 2,137 nt) Show pHMM detection rules used

Region on contig edge.

fungal-RiPP-like: DUF3328

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scaffold_14 - Region 1 - T1PKS

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Location: 103,288 - 171,499 nt. (total: 68,212 nt) Show pHMM detection rules used

T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))

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Predicted core structure(s)

For candidate cluster 1, location 103287 - 171499:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (pk)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

4254585

PKS_AT (891..1181): pk

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 54.2%

minowa: Methoxymalonyl-CoA

Prediction, score:

Methoxymalonyl-CoA: 45.7
Malonyl-CoA: 40.5
Methylmalonyl-CoA: 34.2
trans-1,2-CPDA: 16.1
CHC-CoA: 15.3
inactive: 15.2
Ethylmalonyl-CoA: 14.4
Propionyl-CoA: 14.1
2-Methylbutyryl-CoA: 9.4
fatty_acid: 9.2
Benzoyl-CoA: 9.2
Isobutyryl-CoA: 0.0
Acetyl-CoA: 0.0
3-Methylbutyryl-CoA: 0.0

scaffold_141 - Region 1 - indole

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Location: 57,009 - 88,076 nt. (total: 31,068 nt) Show pHMM detection rules used

Region on contig edge.

indole: (indsynth or dmat or indole_PTase)

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scaffold_150 - Region 1 - T1PKS

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Location: 33,035 - 85,305 nt. (total: 52,271 nt) Show pHMM detection rules used

Region on contig edge.

T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))

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Predicted core structure(s)

For candidate cluster 1, location 33034 - 85305:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (pk)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

4047069

PKS_AT (552..886): pk

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 79.2%; Methylmalonyl-CoA: 66.7%; Ethylmalonyl-CoA: 58.3%

minowa: Methylmalonyl-CoA

Prediction, score:

Methylmalonyl-CoA: 60.3
Methoxymalonyl-CoA: 60.2
Isobutyryl-CoA: 29.5
Malonyl-CoA: 27.0
Ethylmalonyl-CoA: 24.0
Propionyl-CoA: 23.4
fatty_acid: 19.7
2-Methylbutyryl-CoA: 14.5
Benzoyl-CoA: 14.4
inactive: 13.1
CHC-CoA: 10.1
trans-1,2-CPDA: 7.5
Acetyl-CoA: 0.0
3-Methylbutyryl-CoA: 0.0

scaffold_157 - Region 1 - indole

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Location: 20,736 - 51,991 nt. (total: 31,256 nt) Show pHMM detection rules used

indole: (indsynth or dmat or indole_PTase)

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scaffold_164 - Region 1 - T1PKS

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Location: 41,114 - 82,269 nt. (total: 41,156 nt) Show pHMM detection rules used

Region on contig edge.

T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))

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Predicted core structure(s)

For candidate cluster 1, location 41113 - 82269:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (pk)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

4019798

PKS_AT (610..914): pk

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 79.2%; Methylmalonyl-CoA: 66.7%; Methoxymalonyl-CoA: 58.3%

minowa: Methylmalonyl-CoA

Prediction, score:

Methylmalonyl-CoA: 91.5
Methoxymalonyl-CoA: 79.4
Malonyl-CoA: 58.5
Isobutyryl-CoA: 53.7
Propionyl-CoA: 42.1
Benzoyl-CoA: 38.1
trans-1,2-CPDA: 36.3
fatty_acid: 19.9
CHC-CoA: 17.2
2-Methylbutyryl-CoA: 16.0
inactive: 12.4
Acetyl-CoA: 11.2
3-Methylbutyryl-CoA: 10.4
Ethylmalonyl-CoA: -2.2

scaffold_169 - Region 1 - NRPS,T1PKS

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Location: 32,047 - 81,096 nt. (total: 49,050 nt) Show pHMM detection rules used

Region on contig edge.

T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))
NRPS: cds(Condensation and (AMP-binding or A-OX))

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Predicted core structure(s)

For candidate cluster 1, location 32046 - 81096:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (pk - X)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

4061479

PKS_AT (555..870): pk

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 75.0%; Methoxymalonyl-CoA: 62.5%; Methylmalonyl-CoA: 62.5%

minowa: Methylmalonyl-CoA

Prediction, score:

Methylmalonyl-CoA: 95.7
Methoxymalonyl-CoA: 75.9
Ethylmalonyl-CoA: 62.3
trans-1,2-CPDA: 44.0
Isobutyryl-CoA: 42.2
Malonyl-CoA: 39.0
Propionyl-CoA: 37.3
Benzoyl-CoA: 35.6
2-Methylbutyryl-CoA: 21.3
fatty_acid: 19.8
CHC-CoA: 18.7
Acetyl-CoA: 12.0
3-Methylbutyryl-CoA: 10.1
inactive: 0.0

AMP-binding (3024..3423): X

nrpys: Ala, Gly, Val, Leu, Ile, Abu, Ival, Ser, Thr, Hpg, Dhpg, Cys, Pro, Hpr

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic (Ala, Gly, Val, Leu, Ile, Abu, Ival, Ser, Thr, Hpg, Dhpg, Cys, Pro, Hpr)
Large clusters prediction:: N/A
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: DVTYLAVCGK
Nearest Stachelhaus code(s):: Ala DVFSLAVVYK (53% 8� match)
Stachelhaus code match:: 60% (weak)

scaffold_18 - Region 1 - T1PKS

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Location: 1 - 32,331 nt. (total: 32,331 nt) Show pHMM detection rules used

Region on contig edge.

T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))

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NRPS/PKS monomers

NRPS/PKS monomer predictions

4042847

PKS_AT (419..580): mmal

ATSignature: (unknown)

No matches above 50%

minowa: Methylmalonyl-CoA

Prediction, score:

Methylmalonyl-CoA: 19.5
Methoxymalonyl-CoA: 17.5
Malonyl-CoA: 11.0
Ethylmalonyl-CoA: 10.1
trans-1,2-CPDA: 0.0
inactive: 0.0
fatty_acid: 0.0
Propionyl-CoA: 0.0
Isobutyryl-CoA: 0.0
CHC-CoA: 0.0
Benzoyl-CoA: 0.0
Acetyl-CoA: 0.0
3-Methylbutyryl-CoA: 0.0
2-Methylbutyryl-CoA: 0.0

scaffold_185 - Region 1 - NRPS-like

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Location: 17,121 - 77,591 nt. (total: 60,471 nt) Show pHMM detection rules used

Region on contig edge.

NRPS-like: cds((PP-binding or NAD_binding_4) and (AMP-binding or A-OX))

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Predicted core structure(s)

For candidate cluster 1, location 17120 - 77591:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (X)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

4061800

AMP-binding (72..485): X

nrpys: Ala, Gly, Val, Leu, Ile, Abu, Ival, Ser, Thr, Hpg, Dhpg, Cys, Pro, Hpr

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic (Ala, Gly, Val, Leu, Ile, Abu, Ival, Ser, Thr, Hpg, Dhpg, Cys, Pro, Hpr)
Large clusters prediction:: N/A
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: IALISSTLLK
Nearest Stachelhaus code(s):
Stachelhaus code match:: 0% (weak)

scaffold_186 - Region 1 - fungal-RiPP-like

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Location: 1 - 76,552 nt. (total: 76,552 nt) Show pHMM detection rules used

Region on contig edge.

fungal-RiPP-like: DUF3328

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scaffold_188 - Region 1 - terpene

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Location: 1 - 25,030 nt. (total: 25,030 nt) Show pHMM detection rules used

Region on contig edge.

terpene: (Terpene_synth or Terpene_synth_C or phytoene_synt or Lycopene_cycl or terpene_cyclase or NapT7 or fung_ggpps or fung_ggpps2 or trichodiene_synth or TRI5)

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scaffold_19 - Region 1 - fungal-RiPP-like

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Location: 1 - 59,164 nt. (total: 59,164 nt) Show pHMM detection rules used

Region on contig edge.

fungal-RiPP-like: DUF3328

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scaffold_195 - Region 1 - T1PKS

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Location: 1 - 60,390 nt. (total: 60,390 nt) Show pHMM detection rules used

Region on contig edge.

T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))

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Predicted core structure(s)

For candidate cluster 1, location 0 - 60390:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (pk)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

4061990

PKS_AT (603..922): pk

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 75.0%; Methylmalonyl-CoA: 58.3%; Ethylmalonyl-CoA: 54.2%

minowa: Methylmalonyl-CoA

Prediction, score:

Methylmalonyl-CoA: 81.1
Methoxymalonyl-CoA: 76.4
Malonyl-CoA: 63.6
Ethylmalonyl-CoA: 50.5
Isobutyryl-CoA: 32.7
fatty_acid: 24.2
trans-1,2-CPDA: 24.0
Propionyl-CoA: 17.5
Benzoyl-CoA: 16.2
3-Methylbutyryl-CoA: 14.5
inactive: 13.1
CHC-CoA: 11.4
2-Methylbutyryl-CoA: 8.7
Acetyl-CoA: 6.5

scaffold_199 - Region 1 - fungal-RiPP-like

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Location: 1 - 73,946 nt. (total: 73,946 nt) Show pHMM detection rules used

Region on contig edge.

fungal-RiPP-like: DUF3328

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scaffold_207 - Region 1 - NRPS-like

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Location: 3,589 - 67,586 nt. (total: 63,998 nt) Show pHMM detection rules used

NRPS-like: cds((PP-binding or NAD_binding_4) and (AMP-binding or A-OX))

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NRPS/PKS monomers

NRPS/PKS monomer predictions

1033328

AMP-binding (263..657): X

nrpys: Arg, Asp, Glu, Asn, Lys, Gln, Orn, Aad

SVM prediction details:

Predicted physicochemical class:: hydrophilic (Arg, Asp, Glu, Asn, Lys, Gln, Orn, Aad)
Large clusters prediction:: N/A
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: DVMHSGCACK
Nearest Stachelhaus code(s):: Glu DVTHSGSVTK (62% 8� match); Leu DAMLVGAACK (50% 8� match); Hpg DVYHLGLLCK (44% 8� match)
Stachelhaus code match:: 60% (weak)

scaffold_21 - Region 1 - fungal-RiPP-like

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Location: 12,915 - 104,059 nt. (total: 91,145 nt) Show pHMM detection rules used

fungal-RiPP-like: DUF3328

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scaffold_210 - Region 1 - NRPS-like

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Location: 1,263 - 64,615 nt. (total: 63,353 nt) Show pHMM detection rules used

NRPS-like: cds((PP-binding or NAD_binding_4) and (AMP-binding or A-OX))

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NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 1, location 1262 - 64615:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (X)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

4022117

AMP-binding (36..447): X

nrpys: Ala, Gly, Val, Leu, Ile, Abu, Ival, Ser, Thr, Hpg, Dhpg, Cys, Pro, Hpr

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic (Ala, Gly, Val, Leu, Ile, Abu, Ival, Ser, Thr, Hpg, Dhpg, Cys, Pro, Hpr)
Large clusters prediction:: N/A
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: GGFFTAIAVK
Nearest Stachelhaus code(s):: Ile or Val DGLFVGIAVK (35% 8� match)
Stachelhaus code match:: 60% (weak)

scaffold_216 - Region 1 - fungal-RiPP-like

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Location: 1 - 71,092 nt. (total: 71,092 nt) Show pHMM detection rules used

Region on contig edge.

fungal-RiPP-like: DUF3328

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scaffold_224 - Region 1 - fungal-RiPP-like

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Location: 1 - 65,582 nt. (total: 65,582 nt) Show pHMM detection rules used

Region on contig edge.

fungal-RiPP-like: DUF3328

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scaffold_23 - Region 1 - NRPS-like

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Location: 147,473 - 199,431 nt. (total: 51,959 nt) Show pHMM detection rules used

Region on contig edge.

NRPS-like: cds((PP-binding or NAD_binding_4) and (AMP-binding or A-OX))

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Predicted core structure(s)

For candidate cluster 1, location 147472 - 199431:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (X)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

1204437

AMP-binding (23..342): X

nrpys: (unknown)

SVM prediction details:

Predicted physicochemical class:: N/A
Large clusters prediction:: N/A
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: -ANAMAH--K
Nearest Stachelhaus code(s):
Stachelhaus code match:: 0% (weak)

scaffold_230 - Region 1 - terpene

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Location: 23,969 - 55,195 nt. (total: 31,227 nt) Show pHMM detection rules used

terpene: (Terpene_synth or Terpene_synth_C or phytoene_synt or Lycopene_cycl or terpene_cyclase or NapT7 or fung_ggpps or fung_ggpps2 or trichodiene_synth or TRI5)

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scaffold_260 - Region 1 - T1PKS

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Location: 1 - 41,023 nt. (total: 41,023 nt) Show pHMM detection rules used

Region on contig edge.

T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))

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Predicted core structure(s)

For candidate cluster 1, location 0 - 41023:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (mal)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

4063179

PKS_AT (907..1205): mal

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 91.7%; inactive: 58.3%; Methylmalonyl-CoA: 54.2%

minowa: Malonyl-CoA

Prediction, score:

Malonyl-CoA: 82.4
inactive: 45.9
Methoxymalonyl-CoA: 34.1
Methylmalonyl-CoA: 28.3
fatty_acid: 20.7
Propionyl-CoA: 11.6
2-Methylbutyryl-CoA: 10.5
Isobutyryl-CoA: 9.4
Benzoyl-CoA: 9.2
trans-1,2-CPDA: 0.0
Ethylmalonyl-CoA: 0.0
CHC-CoA: 0.0
Acetyl-CoA: 0.0
3-Methylbutyryl-CoA: 0.0

scaffold_270 - Region 1 - T1PKS

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Location: 1 - 35,313 nt. (total: 35,313 nt) Show pHMM detection rules used

Region on contig edge.

T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))

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NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 1, location 0 - 35313:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (pk)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

1481688

PKS_AT (532..824): pk

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 75.0%; Methylmalonyl-CoA: 70.8%; CE-Malonyl-CoA: 62.5%

minowa: Methylmalonyl-CoA

Prediction, score:

Methylmalonyl-CoA: 106.5
Methoxymalonyl-CoA: 90.1
Ethylmalonyl-CoA: 80.2
Malonyl-CoA: 59.4
Isobutyryl-CoA: 58.4
Propionyl-CoA: 46.1
Acetyl-CoA: 43.4
2-Methylbutyryl-CoA: 43.4
trans-1,2-CPDA: 35.7
Benzoyl-CoA: 33.5
3-Methylbutyryl-CoA: 29.7
fatty_acid: 24.8
CHC-CoA: 14.1
inactive: 0.0

scaffold_273 - Region 1 - NRPS

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Location: 1 - 47,207 nt. (total: 47,207 nt) Show pHMM detection rules used

Region on contig edge.

NRPS: cds(Condensation and (AMP-binding or A-OX))

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Predicted core structure(s)

For candidate cluster 1, location 0 - 47207:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (D-X - X - X - D-X)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

4049374

AMP-binding (245..641): X

nrpys: nDodec

SVM prediction details:

Predicted physicochemical class:: N/A
Large clusters prediction:: N/A
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: DVLFVGGVAK
Nearest Stachelhaus code(s):: nDodec DVLFIGGVAK (79% 8� match)
Stachelhaus code match:: 90% (moderate)

AMP-binding (1784..2187): X

nrpys: Ala, Gly, Val, Leu, Ile, Abu, Ival, Ser, Thr, Hpg, Dhpg, Cys, Pro, Hpr

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic (Ala, Gly, Val, Leu, Ile, Abu, Ival, Ser, Thr, Hpg, Dhpg, Cys, Pro, Hpr)
Large clusters prediction:: N/A
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: DVQDSGVVTK
Nearest Stachelhaus code(s):: dn-dohHep DVFDFGGVTK (59% 8� match); Gln or Glu DAQDLGVVDK (56% 8� match); Ile DAQDLGVVDK (53% 8� match); Ahp DVENAGVVTK (44% 8� match)
Stachelhaus code match:: 70% (weak)

AMP-binding (2903..3298): X

nrpys: (unknown)

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic (Ala, Gly, Val, Leu, Ile, Abu, Ival, Ser, Thr, Hpg, Dhpg, Cys, Pro, Hpr)
Large clusters prediction:: Apolar, aliphatic (Gly, Ala, Val, Leu, Ile, Abu, Ival)
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: DVSFAGSIWK
Nearest Stachelhaus code(s):: Asn DVAFTGSIWK (76% 8� match)
Stachelhaus code match:: 80% (moderate)

AMP-binding (3979..4371): X

nrpys: (unknown)

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic (Ala, Gly, Val, Leu, Ile, Abu, Ival, Ser, Thr, Hpg, Dhpg, Cys, Pro, Hpr)
Large clusters prediction:: Apolar, aliphatic (Gly, Ala, Val, Leu, Ile, Abu, Ival)
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: DVGYSGIIWK
Nearest Stachelhaus code(s):: Ser DVAYSGMIWK (74% 8� match)
Stachelhaus code match:: 80% (moderate)

scaffold_276 - Region 1 - fungal-RiPP-like

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Location: 1 - 59,975 nt. (total: 59,975 nt) Show pHMM detection rules used

Region on contig edge.

fungal-RiPP-like: DUF3328

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No matches found.

scaffold_302 - Region 1 - NRPS

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Location: 1 - 55,812 nt. (total: 55,812 nt) Show pHMM detection rules used

Region on contig edge.

NRPS: cds(Condensation and (AMP-binding or A-OX))

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No matches found.

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NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 1, location 0 - 55812:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (Ala)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

1686749

Search NORINE for peptide: strict or relaxed

AMP-binding (61..462): Ala

nrpys: Ala

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic (Ala, Gly, Val, Leu, Ile, Abu, Ival, Ser, Thr, Hpg, Dhpg, Cys, Pro, Hpr)
Large clusters prediction:: N/A
Small clusters prediction:: Tiny, hydrophilic, transition to aliphatic (Gly, Ala)
Single AA prediction:: ala (Ala)

Stachelhaus prediction details:

Stachelhaus sequence:: AMFACSGPIK
Nearest Stachelhaus code(s):
Stachelhaus code match:: 0% (weak)

scaffold_306 - Region 1 - T1PKS

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Location: 1 - 55,126 nt. (total: 55,126 nt) Show pHMM detection rules used

Region on contig edge.

T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))

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Predicted core structure(s)

For candidate cluster 1, location 0 - 55126:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (mal)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

4063893

PKS_AT (924..1219): mal

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 54.2%

minowa: inactive

Prediction, score:

inactive: 52.7
Malonyl-CoA: 52.3
Methoxymalonyl-CoA: 50.0
Methylmalonyl-CoA: 43.1
Ethylmalonyl-CoA: 28.2
Propionyl-CoA: 28.0
CHC-CoA: 25.5
2-Methylbutyryl-CoA: 19.1
trans-1,2-CPDA: 17.4
Isobutyryl-CoA: 15.9
Benzoyl-CoA: 14.5
3-Methylbutyryl-CoA: 12.5
Acetyl-CoA: 12.3
fatty_acid: 11.7

scaffold_307 - Region 1 - T1PKS

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Location: 13,874 - 54,899 nt. (total: 41,026 nt) Show pHMM detection rules used

Region on contig edge.

T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))

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No matches found.

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NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 1, location 13873 - 54899:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (pk)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

4215243

PKS_AT (530..843): pk

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 83.3%; Methylmalonyl-CoA: 62.5%; Isobutyryl-CoA: 62.5%

minowa: Methylmalonyl-CoA

Prediction, score:

Methylmalonyl-CoA: 93.2
Methoxymalonyl-CoA: 88.1
Malonyl-CoA: 69.4
Isobutyryl-CoA: 66.5
Propionyl-CoA: 48.5
Ethylmalonyl-CoA: 45.7
Benzoyl-CoA: 40.5
inactive: 38.9
2-Methylbutyryl-CoA: 31.3
3-Methylbutyryl-CoA: 22.2
trans-1,2-CPDA: 21.7
CHC-CoA: 13.8
Acetyl-CoA: 12.6
fatty_acid: 12.5

4026329

AMP-binding (48..492): X

nrpys: Val, Leu, Ile, Abu, Ival

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic (Ala, Gly, Val, Leu, Ile, Abu, Ival, Ser, Thr, Hpg, Dhpg, Cys, Pro, Hpr)
Large clusters prediction:: N/A
Small clusters prediction:: Aliphatic, branched hydrophobic (Val, Leu, Ile, Abu, Ival)
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: GSGYISCPVK
Nearest Stachelhaus code(s):
Stachelhaus code match:: 0% (weak)

scaffold_309 - Region 1 - T1PKS

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Location: 15,741 - 54,865 nt. (total: 39,125 nt) Show pHMM detection rules used

Region on contig edge.

T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))

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Predicted core structure(s)

For candidate cluster 1, location 15740 - 54865:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (pk)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

4260445

PKS_AT (637..968): pk

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 75.0%; Methylmalonyl-CoA: 62.5%; Ethylmalonyl-CoA: 58.3%

minowa: Methylmalonyl-CoA

Prediction, score:

Methylmalonyl-CoA: 72.3
Methoxymalonyl-CoA: 65.6
Malonyl-CoA: 60.8
Propionyl-CoA: 38.1
Ethylmalonyl-CoA: 32.1
inactive: 18.9
CHC-CoA: 16.8
Benzoyl-CoA: 13.5
Isobutyryl-CoA: 9.3
2-Methylbutyryl-CoA: 3.8
trans-1,2-CPDA: 0.0
fatty_acid: 0.0
3-Methylbutyryl-CoA: 0.0
Acetyl-CoA: -0.8

scaffold_32 - Region 1 - NRPS-like

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Location: 125,185 - 174,200 nt. (total: 49,016 nt) Show pHMM detection rules used

Region on contig edge.

NRPS-like: cds((PP-binding or NAD_binding_4) and (AMP-binding or A-OX))

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No matches found.

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Predicted core structure(s)

For candidate cluster 1, location 125184 - 174200:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (X)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

4057498

AMP-binding (28..430): X

nrpys: (unknown)

SVM prediction details:

Predicted physicochemical class:: hydrophilic (Arg, Asp, Glu, Asn, Lys, Gln, Orn, Aad)
Large clusters prediction:: N/A
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: VATFPGAAGK
Nearest Stachelhaus code(s):: Ppa VATFIGGAGK (74% 8� match)
Stachelhaus code match:: 80% (moderate)

scaffold_321 - Region 1 - NRPS-like

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Location: 1 - 37,896 nt. (total: 37,896 nt) Show pHMM detection rules used

Region on contig edge.

NRPS-like: cds((PP-binding or NAD_binding_4) and (AMP-binding or A-OX))

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No matches found.

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Predicted core structure(s)

For candidate cluster 1, location 0 - 37896:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (X)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

4179876

AMP-binding (45..379): X

nrpys: Ala, Gly, Val, Leu, Ile, Abu, Ival, Ser, Thr, Hpg, Dhpg, Cys, Pro, Hpr

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic (Ala, Gly, Val, Leu, Ile, Abu, Ival, Ser, Thr, Hpg, Dhpg, Cys, Pro, Hpr)
Large clusters prediction:: N/A
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: -VFYISYQIK
Nearest Stachelhaus code(s):: Pro DVQYISGVIK (38% 8� match)
Stachelhaus code match:: 60% (weak)

scaffold_325 - Region 1 - indole

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Location: 1 - 29,624 nt. (total: 29,624 nt) Show pHMM detection rules used

Region on contig edge.

indole: (indsynth or dmat or indole_PTase)

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No matches found.

scaffold_327 - Region 1 - terpene

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Location: 23,394 - 52,703 nt. (total: 29,310 nt) Show pHMM detection rules used

Region on contig edge.

terpene: (Terpene_synth or Terpene_synth_C or phytoene_synt or Lycopene_cycl or terpene_cyclase or NapT7 or fung_ggpps or fung_ggpps2 or trichodiene_synth or TRI5)

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scaffold_345 - Region 1 - fungal-RiPP-like

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Location: 1 - 50,859 nt. (total: 50,859 nt) Show pHMM detection rules used

Region on contig edge.

fungal-RiPP-like: DUF3328

Legend:

core biosynthetic genes

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scaffold_363 - Region 1 - fungal-RiPP-like

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Location: 1 - 48,434 nt. (total: 48,434 nt) Show pHMM detection rules used

Region on contig edge.

fungal-RiPP-like: DUF3328

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scaffold_365 - Region 1 - NRPS

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Location: 1 - 48,247 nt. (total: 48,247 nt) Show pHMM detection rules used

Region on contig edge.

NRPS: cds(Condensation and (AMP-binding or A-OX))

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NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 1, location 0 - 48247:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (X - X)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

2026815

AMP-binding (57..442): X

nrpys: Asp, Asn, Glu, Gln, Aad

SVM prediction details:

Predicted physicochemical class:: hydrophilic (Arg, Asp, Glu, Asn, Lys, Gln, Orn, Aad)
Large clusters prediction:: Aliphatic chain with H-bond donor (Asp, Asn, Glu, Gln, Aad)
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: SARESGAQLK
Nearest Stachelhaus code(s):
Stachelhaus code match:: 0% (weak)

AMP-binding (1092..1481): X

nrpys: Gly, Ala, Val, Leu, Ile, Abu, Ival

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic (Ala, Gly, Val, Leu, Ile, Abu, Ival, Ser, Thr, Hpg, Dhpg, Cys, Pro, Hpr)
Large clusters prediction:: Apolar, aliphatic (Gly, Ala, Val, Leu, Ile, Abu, Ival)
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: DAYMNCGILK
Nearest Stachelhaus code(s):: Val DAWMFAAILK (53% 8� match)
Stachelhaus code match:: 60% (weak)

scaffold_37 - Region 1 - fungal-RiPP-like

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Location: 1,092 - 91,888 nt. (total: 90,797 nt) Show pHMM detection rules used

fungal-RiPP-like: DUF3328

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scaffold_372 - Region 1 - fungal-RiPP-like

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Location: 1 - 47,340 nt. (total: 47,340 nt) Show pHMM detection rules used

Region on contig edge.

fungal-RiPP-like: DUF3328

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scaffold_386 - Region 1 - terpene

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Location: 23,488 - 46,453 nt. (total: 22,966 nt) Show pHMM detection rules used

Region on contig edge.

terpene: (Terpene_synth or Terpene_synth_C or phytoene_synt or Lycopene_cycl or terpene_cyclase or NapT7 or fung_ggpps or fung_ggpps2 or trichodiene_synth or TRI5)

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scaffold_404 - Region 1 - T1PKS,terpene

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Location: 1 - 44,698 nt. (total: 44,698 nt) Show pHMM detection rules used

Region on contig edge.

T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))
terpene: (Terpene_synth or Terpene_synth_C or phytoene_synt or Lycopene_cycl or terpene_cyclase or NapT7 or fung_ggpps or fung_ggpps2 or trichodiene_synth or TRI5)

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NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 1, location 0 - 44698:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (pk)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

4029667

PKS_AT (570..889): pk

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 70.8%; Methylmalonyl-CoA: 58.3%; Propionyl-CoA: 54.2%

minowa: Methylmalonyl-CoA

Prediction, score:

Methylmalonyl-CoA: 72.8
Methoxymalonyl-CoA: 68.3
Malonyl-CoA: 59.7
Isobutyryl-CoA: 51.6
Ethylmalonyl-CoA: 42.9
Propionyl-CoA: 28.6
3-Methylbutyryl-CoA: 24.4
Benzoyl-CoA: 24.3
inactive: 19.7
fatty_acid: 12.0
2-Methylbutyryl-CoA: 7.1
trans-1,2-CPDA: 4.9
CHC-CoA: 0.0
Acetyl-CoA: 0.0

scaffold_41 - Region 1 - NRPS

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Location: 1 - 77,465 nt. (total: 77,465 nt) Show pHMM detection rules used

Region on contig edge.

NRPS: cds(Condensation and (AMP-binding or A-OX))

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Predicted core structure(s)

For candidate cluster 1, location 0 - 77465:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (X - X) + (Pro)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

4174270

AMP-binding (856..1250): X

nrpys: Ala, Gly, Val, Leu, Ile, Abu, Ival, Ser, Thr, Hpg, Dhpg, Cys, Pro, Hpr

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic (Ala, Gly, Val, Leu, Ile, Abu, Ival, Ser, Thr, Hpg, Dhpg, Cys, Pro, Hpr)
Large clusters prediction:: N/A
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: DISNVAAILK
Nearest Stachelhaus code(s):: bOH-Tyr DTSKVAAICK (56% 8� match)
Stachelhaus code match:: 70% (weak)

AMP-binding (1944..2346): X

nrpys: (unknown)

SVM prediction details:

Predicted physicochemical class:: N/A
Large clusters prediction:: N/A
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: DVQSVNSINK
Nearest Stachelhaus code(s):: Gln DVQIVGGIHK (76% 8� match); bOH-Gln DAQNIASINK (68% 8� match); Arg DVENVGAINK (41% 8� match)
Stachelhaus code match:: 60% (weak)

4011015

AMP-binding (38..458): X

nrpys: Ala, Gly, Val, Leu, Ile, Abu, Ival, Ser, Thr, Hpg, Dhpg, Cys, Pro, Hpr

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic (Ala, Gly, Val, Leu, Ile, Abu, Ival, Ser, Thr, Hpg, Dhpg, Cys, Pro, Hpr)
Large clusters prediction:: N/A
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: GLGYVGGVIK
Nearest Stachelhaus code(s):: nohBza GLGLVGAIIK (35% 8� match); Abu DLGYVAGVFK (29% 8� match)
Stachelhaus code match:: 70% (weak)

4279232

Search NORINE for peptide: strict or relaxed

AMP-binding (474..870): Pro

nrpys: Pro

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic (Ala, Gly, Val, Leu, Ile, Abu, Ival, Ser, Thr, Hpg, Dhpg, Cys, Pro, Hpr)
Large clusters prediction:: Cyclic aliphatic chain (polar NH2 group) (Pro, Hpr)
Small clusters prediction:: pro (Pro)
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: DIQSAVGAIK
Nearest Stachelhaus code(s):
Stachelhaus code match:: 0% (weak)

scaffold_410 - Region 1 - terpene

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Location: 23,245 - 43,963 nt. (total: 20,719 nt) Show pHMM detection rules used

Region on contig edge.

terpene: (Terpene_synth or Terpene_synth_C or phytoene_synt or Lycopene_cycl or terpene_cyclase or NapT7 or fung_ggpps or fung_ggpps2 or trichodiene_synth or TRI5)

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scaffold_413 - Region 1 - terpene

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Location: 3,460 - 35,652 nt. (total: 32,193 nt) Show pHMM detection rules used

Region on contig edge.

terpene: (Terpene_synth or Terpene_synth_C or phytoene_synt or Lycopene_cycl or terpene_cyclase or NapT7 or fung_ggpps or fung_ggpps2 or trichodiene_synth or TRI5)

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No matches found.

scaffold_43 - Region 1 - terpene

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Location: 114,732 - 145,388 nt. (total: 30,657 nt) Show pHMM detection rules used

Region on contig edge.

terpene: (Terpene_synth or Terpene_synth_C or phytoene_synt or Lycopene_cycl or terpene_cyclase or NapT7 or fung_ggpps or fung_ggpps2 or trichodiene_synth or TRI5)

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scaffold_446 - Region 1 - fungal-RiPP-like

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Location: 1 - 40,162 nt. (total: 40,162 nt) Show pHMM detection rules used

Region on contig edge.

fungal-RiPP-like: DUF3328

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scaffold_456 - Region 1 - T1PKS

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Location: 2,437 - 39,616 nt. (total: 37,180 nt) Show pHMM detection rules used

Region on contig edge.

T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))

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No matches found.

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NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 1, location 2436 - 39616:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (mal)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

4181367

PKS_AT (825..1115): mal

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 75.0%; inactive: 54.2%

minowa: Malonyl-CoA

Prediction, score:

Malonyl-CoA: 98.7
Methoxymalonyl-CoA: 59.8
Methylmalonyl-CoA: 54.2
inactive: 43.9
Propionyl-CoA: 28.5
Ethylmalonyl-CoA: 25.7
2-Methylbutyryl-CoA: 21.6
CHC-CoA: 18.6
fatty_acid: 17.9
Benzoyl-CoA: 13.6
3-Methylbutyryl-CoA: 13.3
Isobutyryl-CoA: 12.5
Acetyl-CoA: 9.1
trans-1,2-CPDA: 8.8

scaffold_474 - Region 1 - T1PKS

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Location: 1 - 38,282 nt. (total: 38,282 nt) Show pHMM detection rules used

Region on contig edge.

T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))

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Predicted core structure(s)

For candidate cluster 1, location 0 - 38282:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (mal)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

4031635

PKS_AT (905..1203): mal

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 83.3%; inactive: 58.3%; Methylmalonyl-CoA: 54.2%

minowa: Malonyl-CoA

Prediction, score:

Malonyl-CoA: 122.0
Methylmalonyl-CoA: 70.7
Methoxymalonyl-CoA: 70.7
inactive: 69.9
Propionyl-CoA: 44.2
Ethylmalonyl-CoA: 36.6
Acetyl-CoA: 33.0
2-Methylbutyryl-CoA: 26.3
CHC-CoA: 23.9
Benzoyl-CoA: 20.2
Isobutyryl-CoA: 19.4
3-Methylbutyryl-CoA: 17.4
fatty_acid: 16.5
trans-1,2-CPDA: 12.3

scaffold_476 - Region 1 - T1PKS

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Location: 1 - 38,166 nt. (total: 38,166 nt) Show pHMM detection rules used

Region on contig edge.

T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))

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NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 1, location 0 - 38166:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (mal)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

4031692

PKS_AT (909..1205): mal

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 83.3%; Methylmalonyl-CoA: 58.3%; Isobutyryl-CoA: 58.3%

minowa: Malonyl-CoA

Prediction, score:

Malonyl-CoA: 107.7
Methylmalonyl-CoA: 71.6
Methoxymalonyl-CoA: 61.7
inactive: 56.0
Propionyl-CoA: 53.8
2-Methylbutyryl-CoA: 38.8
CHC-CoA: 21.3
Ethylmalonyl-CoA: 18.8
Isobutyryl-CoA: 18.2
Benzoyl-CoA: 17.6
fatty_acid: 15.2
Acetyl-CoA: 14.5
3-Methylbutyryl-CoA: 14.5
trans-1,2-CPDA: 11.4

scaffold_478 - Region 1 - T1PKS

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Location: 1 - 37,891 nt. (total: 37,891 nt) Show pHMM detection rules used

Region on contig edge.

T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))

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Predicted core structure(s)

For candidate cluster 1, location 0 - 37891:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (mal)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

2496129

PKS_AT (919..1213): mal

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 62.5%; Ethylmalonyl-CoA: 54.2%; inactive: 54.2%

minowa: Malonyl-CoA

Prediction, score:

Malonyl-CoA: 65.9
Methoxymalonyl-CoA: 60.6
Methylmalonyl-CoA: 54.8
inactive: 48.4
Ethylmalonyl-CoA: 30.8
Propionyl-CoA: 23.0
CHC-CoA: 22.1
fatty_acid: 21.3
2-Methylbutyryl-CoA: 16.7
trans-1,2-CPDA: 14.4
3-Methylbutyryl-CoA: 13.5
Isobutyryl-CoA: 13.0
Acetyl-CoA: 12.5
Benzoyl-CoA: 9.0

scaffold_526 - Region 1 - T1PKS

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Location: 1 - 34,474 nt. (total: 34,474 nt) Show pHMM detection rules used

Region on contig edge.

T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))

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Predicted core structure(s)

For candidate cluster 1, location 0 - 34474:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (mal)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

4066452

PKS_AT (910..1200): mal

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 79.2%; inactive: 58.3%

minowa: Malonyl-CoA

Prediction, score:

Malonyl-CoA: 111.4
inactive: 78.0
Methoxymalonyl-CoA: 57.3
Methylmalonyl-CoA: 48.5
Propionyl-CoA: 29.5
fatty_acid: 13.6
Acetyl-CoA: 13.2
2-Methylbutyryl-CoA: 12.3
Ethylmalonyl-CoA: 9.8
trans-1,2-CPDA: 9.1
Isobutyryl-CoA: 8.1
CHC-CoA: 7.2
Benzoyl-CoA: 7.2
3-Methylbutyryl-CoA: 0.0

scaffold_53 - Region 1 - NRPS-like

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Location: 98,316 - 135,428 nt. (total: 37,113 nt) Show pHMM detection rules used

Region on contig edge.

NRPS-like: cds((PP-binding or NAD_binding_4) and (AMP-binding or A-OX))

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Predicted core structure(s)

For candidate cluster 1, location 98315 - 135428:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (X)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

2713010

AMP-binding (33..455): X

nrpys: (unknown)

SVM prediction details:

Predicted physicochemical class:: hydrophilic (Arg, Asp, Glu, Asn, Lys, Gln, Orn, Aad)
Large clusters prediction:: N/A
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: VASFIGGAGK
Nearest Stachelhaus code(s):: Ppa VATFIGGAGK (91% 8� match)
Stachelhaus code match:: 90% (moderate)

scaffold_551 - Region 1 - terpene

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Location: 1 - 27,217 nt. (total: 27,217 nt) Show pHMM detection rules used

Region on contig edge.

terpene: (Terpene_synth or Terpene_synth_C or phytoene_synt or Lycopene_cycl or terpene_cyclase or NapT7 or fung_ggpps or fung_ggpps2 or trichodiene_synth or TRI5)

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scaffold_569 - Region 1 - T1PKS

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Location: 1 - 31,556 nt. (total: 31,556 nt) Show pHMM detection rules used

Region on contig edge.

T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))

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NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 1, location 0 - 31556:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (mal)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

4066815

PKS_AT (904..1200): mal

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 75.0%; Methylmalonyl-CoA: 54.2%

minowa: Malonyl-CoA

Prediction, score:

Malonyl-CoA: 103.8
Methylmalonyl-CoA: 61.1
Methoxymalonyl-CoA: 57.4
inactive: 46.3
Propionyl-CoA: 34.8
Isobutyryl-CoA: 32.2
2-Methylbutyryl-CoA: 29.7
Ethylmalonyl-CoA: 17.9
Benzoyl-CoA: 16.0
CHC-CoA: 14.3
3-Methylbutyryl-CoA: 12.1
fatty_acid: 10.7
trans-1,2-CPDA: 9.3
Acetyl-CoA: 8.1

scaffold_58 - Region 1 - NRPS,T1PKS

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Location: 1 - 87,917 nt. (total: 87,917 nt) Show pHMM detection rules used

Region on contig edge.

T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))
NRPS: cds(Condensation and (AMP-binding or A-OX))

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Predicted core structure(s)

For candidate cluster 1, location 0 - 87917:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (pk) + (Val - Tyr - Val)

Direct lookup in NORINE database: strict or relaxed

For candidate cluster 2, location 0 - 53599:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (pk) + (Val - Tyr - Val)

Direct lookup in NORINE database: strict or relaxed

For candidate cluster 3, location 18188 - 87917:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (pk) + (Val - Tyr - Val)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

4234711

PKS_AT (517..820): pk

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 75.0%; Methylmalonyl-CoA: 62.5%; Propionyl-CoA: 58.3%

minowa: Methylmalonyl-CoA

Prediction, score:

Methylmalonyl-CoA: 83.3
Methoxymalonyl-CoA: 63.6
Propionyl-CoA: 51.8
Malonyl-CoA: 41.7
fatty_acid: 38.5
Isobutyryl-CoA: 32.7
Benzoyl-CoA: 26.7
2-Methylbutyryl-CoA: 25.0
trans-1,2-CPDA: 23.5
CHC-CoA: 21.1
3-Methylbutyryl-CoA: 10.5
Acetyl-CoA: 5.7
inactive: 0.0
Ethylmalonyl-CoA: -4.2

4044533

AMP-binding (9..336): X

nrpys: Gly, Ala

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic (Ala, Gly, Val, Leu, Ile, Abu, Ival, Ser, Thr, Hpg, Dhpg, Cys, Pro, Hpr)
Large clusters prediction:: Apolar, aliphatic (Gly, Ala, Val, Leu, Ile, Abu, Ival)
Small clusters prediction:: Tiny, hydrophilic, transition to aliphatic (Gly, Ala)
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: DIGCVCAIFK
Nearest Stachelhaus code(s):: Leu DIHFVGAIAK (50% 8� match); Hpg DIWHVGAITK (41% 8� match)
Stachelhaus code match:: 60% (weak)

4090796

Search NORINE for peptide: strict or relaxed

AMP-binding (151..525): Val

nrpys: Val

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic (Ala, Gly, Val, Leu, Ile, Abu, Ival, Ser, Thr, Hpg, Dhpg, Cys, Pro, Hpr)
Large clusters prediction:: Apolar, aliphatic (Gly, Ala, Val, Leu, Ile, Abu, Ival)
Small clusters prediction:: Aliphatic, branched hydrophobic (Val, Leu, Ile, Abu, Ival)
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: DALFVGGIFK
Nearest Stachelhaus code(s):: Val DAMFVGGVFK (56% 8� match)
Stachelhaus code match:: 80% (moderate)

AMP-binding (1203..1597): Tyr

nrpys: Tyr

SVM prediction details:

Predicted physicochemical class:: N/A
Large clusters prediction:: N/A
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: DALALGMVVK
Nearest Stachelhaus code(s):: Tyr DALAVGEVVK (50% 8� match)
Stachelhaus code match:: 80% (moderate)

AMP-binding (2293..2688): Val

nrpys: Val

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic (Ala, Gly, Val, Leu, Ile, Abu, Ival, Ser, Thr, Hpg, Dhpg, Cys, Pro, Hpr)
Large clusters prediction:: Apolar, aliphatic (Gly, Ala, Val, Leu, Ile, Abu, Ival)
Small clusters prediction:: Aliphatic, branched hydrophobic (Val, Leu, Ile, Abu, Ival)
Single AA prediction:: val (Val)

Stachelhaus prediction details:

Stachelhaus sequence:: GAAFIGGTIK
Nearest Stachelhaus code(s):: Val DALFIGGTFK (47% 8� match); Leu or Ile DALFIGGTFK (47% 8� match)
Stachelhaus code match:: 70% (weak)

scaffold_608 - Region 1 - NRPS-like

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Location: 1 - 29,278 nt. (total: 29,278 nt) Show pHMM detection rules used

Region on contig edge.

NRPS-like: cds((PP-binding or NAD_binding_4) and (AMP-binding or A-OX))

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No matches found.

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Predicted core structure(s)

For candidate cluster 1, location 0 - 29278:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (X)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

4067124

AMP-binding (24..403): X

nrpys: Phe, Trp, Ph-Gly, Tyr, bOH-Tyr

SVM prediction details:

Predicted physicochemical class:: N/A
Large clusters prediction:: Aromatic side chain (Phe, Trp, Ph-Gly, Tyr, bOH-Tyr)
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: ---LIGLVLK
Nearest Stachelhaus code(s):
Stachelhaus code match:: 0% (weak)

scaffold_64 - Region 1 - fungal-RiPP-like

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Location: 10,687 - 124,574 nt. (total: 113,888 nt) Show pHMM detection rules used

fungal-RiPP-like: DUF3328

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scaffold_650 - Region 1 - fungal-RiPP-like

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Location: 1 - 26,905 nt. (total: 26,905 nt) Show pHMM detection rules used

Region on contig edge.

fungal-RiPP-like: DUF3328

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scaffold_661 - Region 1 - NRP-metallophore,NRPS

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Location: 1 - 26,542 nt. (total: 26,542 nt) Show pHMM detection rules used

Region on contig edge.

NRP-metallophore: (VibH_like or Cy_tandem or (cds(Condensation and AMP-binding) and ((IBH_Asp and not SBH_Asp) or IBH_His or TBH_Asp or CyanoBH_Asp1 or CyanoBH_Asp2 or IPL or SalSyn or (EntA and EntC) or (GrbD and GrbE) or (FbnL and FbnM) or PvdO or PvdP or (Orn_monoox and not (KtzT or MetRS-like)) or Lys_monoox or VbsL)))
NRPS: cds(Condensation and (AMP-binding or A-OX))

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No matches found.

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NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 1, location 0 - 26542:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (X - X - X)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

4239512

AMP-binding (188..583): X

nrpys: Phe, Tyr, diOH-Bz, Ph-Gly, bOH-Tyr

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aromatic (Phe, Tyr, diOH-Bz, Ph-Gly, bOH-Tyr)
Large clusters prediction:: N/A
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: DVFELIMIHK
Nearest Stachelhaus code(s):: Orn DVSELGTINK (59% 8� match); Dab DVGELSSIDK (44% 8� match); Ser DLFNLGLIHK (38% 8� match)
Stachelhaus code match:: 60% (weak)

AMP-binding (1243..1665): X

nrpys: Gly, Ala, Val, Leu, Ile, Abu, Ival

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic (Ala, Gly, Val, Leu, Ile, Abu, Ival, Ser, Thr, Hpg, Dhpg, Cys, Pro, Hpr)
Large clusters prediction:: Apolar, aliphatic (Gly, Ala, Val, Leu, Ile, Abu, Ival)
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: DVFSVAGNIK
Nearest Stachelhaus code(s):: Ala DVFSVALVYK (62% 8� match)
Stachelhaus code match:: 70% (weak)

AMP-binding (2927..3333): X

nrpys: (unknown)

SVM prediction details:

Predicted physicochemical class:: N/A
Large clusters prediction:: N/A
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: DVLDIGGIGK
Nearest Stachelhaus code(s):: nDodec DVLFIGGVAK (53% 8� match)
Stachelhaus code match:: 70% (weak)

scaffold_672 - Region 1 - NRPS-like

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Location: 1 - 25,650 nt. (total: 25,650 nt) Show pHMM detection rules used

Region on contig edge.

NRPS-like: cds((PP-binding or NAD_binding_4) and (AMP-binding or A-OX))

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Predicted core structure(s)

For candidate cluster 1, location 0 - 25650:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (Aad)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

4156623

Search NORINE for peptide: strict or relaxed

AMP-binding (0..416): Aad

nrpys: Aad

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic (Ala, Gly, Val, Leu, Ile, Abu, Ival, Ser, Thr, Hpg, Dhpg, Cys, Pro, Hpr)
Large clusters prediction:: Aliphatic chain with H-bond donor (Asp, Asn, Glu, Gln, Aad)
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: DPRHFVMRAK
Nearest Stachelhaus code(s):: Aad DPRHFVMRAK (100% 8� match)
Stachelhaus code match:: 100% (strong)

scaffold_683 - Region 1 - terpene

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Location: 1 - 24,964 nt. (total: 24,964 nt) Show pHMM detection rules used

Region on contig edge.

terpene: (Terpene_synth or Terpene_synth_C or phytoene_synt or Lycopene_cycl or terpene_cyclase or NapT7 or fung_ggpps or fung_ggpps2 or trichodiene_synth or TRI5)

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scaffold_690 - Region 1 - fungal-RiPP-like

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Location: 1 - 24,499 nt. (total: 24,499 nt) Show pHMM detection rules used

Region on contig edge.

fungal-RiPP-like: DUF3328

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scaffold_70 - Region 1 - T1PKS

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Location: 54,435 - 121,653 nt. (total: 67,219 nt) Show pHMM detection rules used

T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))

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Predicted core structure(s)

For candidate cluster 1, location 54434 - 121653:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (mal)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

4267823

PKS_AT (529..823): mal

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 58.3%; inactive: 54.2%

minowa: Malonyl-CoA

Prediction, score:

Malonyl-CoA: 55.4
inactive: 50.4
Methoxymalonyl-CoA: 35.7
Methylmalonyl-CoA: 35.4
Propionyl-CoA: 16.3
CHC-CoA: 10.9
Benzoyl-CoA: 10.1
2-Methylbutyryl-CoA: 10.0
Ethylmalonyl-CoA: 9.9
fatty_acid: 9.5
trans-1,2-CPDA: 0.0
Isobutyryl-CoA: 0.0
Acetyl-CoA: 0.0
3-Methylbutyryl-CoA: 0.0

scaffold_701 - Region 1 - T1PKS

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Location: 1 - 23,894 nt. (total: 23,894 nt) Show pHMM detection rules used

Region on contig edge.

T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))

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Predicted core structure(s)

For candidate cluster 1, location 0 - 23894:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (pk)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

4067777

PKS_AT (591..917): pk

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 75.0%; Methylmalonyl-CoA: 66.7%; Ethylmalonyl-CoA: 58.3%

minowa: Methoxymalonyl-CoA

Prediction, score:

Methoxymalonyl-CoA: 80.3
Methylmalonyl-CoA: 75.5
Malonyl-CoA: 66.5
Isobutyryl-CoA: 42.2
Ethylmalonyl-CoA: 37.0
trans-1,2-CPDA: 29.8
inactive: 27.7
CHC-CoA: 27.1
fatty_acid: 25.6
2-Methylbutyryl-CoA: 21.6
3-Methylbutyryl-CoA: 18.6
Propionyl-CoA: 17.9
Benzoyl-CoA: 14.3
Acetyl-CoA: 6.6

scaffold_737 - Region 1 - T1PKS

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Location: 1 - 22,647 nt. (total: 22,647 nt) Show pHMM detection rules used

Region on contig edge.

T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))

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NRPS/PKS monomers

NRPS/PKS monomer predictions

4068009

PKS_AT (498..738): pk

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 66.7%; Methylmalonyl-CoA: 54.2%

minowa: Methoxymalonyl-CoA

Prediction, score:

Methoxymalonyl-CoA: 32.7
Methylmalonyl-CoA: 23.4
Malonyl-CoA: 18.3
fatty_acid: 14.8
Isobutyryl-CoA: 12.2
2-Methylbutyryl-CoA: 10.5
Benzoyl-CoA: 9.6
Ethylmalonyl-CoA: 9.3
trans-1,2-CPDA: 0.0
inactive: 0.0
Propionyl-CoA: 0.0
CHC-CoA: 0.0
Acetyl-CoA: 0.0
3-Methylbutyryl-CoA: 0.0

4159565

AMP-binding (46..348): X

nrpys: Ala, Gly, Val, Leu, Ile, Abu, Ival, Ser, Thr, Hpg, Dhpg, Cys, Pro, Hpr

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic (Ala, Gly, Val, Leu, Ile, Abu, Ival, Ser, Thr, Hpg, Dhpg, Cys, Pro, Hpr)
Large clusters prediction:: N/A
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: HVKVAGF--K
Nearest Stachelhaus code(s):
Stachelhaus code match:: 0% (weak)

scaffold_746 - Region 1 - NRPS

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Location: 1 - 22,272 nt. (total: 22,272 nt) Show pHMM detection rules used

Region on contig edge.

NRPS: cds(Condensation and (AMP-binding or A-OX))

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Predicted core structure(s)

For candidate cluster 1, location 0 - 22272:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (X - X)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

4068072

AMP-binding (265..643): X

nrpys: Asp, Asn, Glu, Gln, Aad

SVM prediction details:

Predicted physicochemical class:: hydrophilic (Arg, Asp, Glu, Asn, Lys, Gln, Orn, Aad)
Large clusters prediction:: Aliphatic chain with H-bond donor (Asp, Asn, Glu, Gln, Aad)
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: SARENGAQMK
Nearest Stachelhaus code(s):
Stachelhaus code match:: 0% (weak)

AMP-binding (1289..1676): X

nrpys: Ala, Gly, Val, Leu, Ile, Abu, Ival, Ser, Thr, Hpg, Dhpg, Cys, Pro, Hpr

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic (Ala, Gly, Val, Leu, Ile, Abu, Ival, Ser, Thr, Hpg, Dhpg, Cys, Pro, Hpr)
Large clusters prediction:: N/A
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: DAYMNCGILK
Nearest Stachelhaus code(s):: Val DAWMFAAILK (50% 8� match)
Stachelhaus code match:: 60% (weak)

scaffold_753 - Region 1 - terpene

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Location: 1 - 16,862 nt. (total: 16,862 nt) Show pHMM detection rules used

Region on contig edge.

terpene: (Terpene_synth or Terpene_synth_C or phytoene_synt or Lycopene_cycl or terpene_cyclase or NapT7 or fung_ggpps or fung_ggpps2 or trichodiene_synth or TRI5)

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No matches found.

scaffold_76 - Region 1 - T1PKS

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Location: 18,173 - 84,960 nt. (total: 66,788 nt) Show pHMM detection rules used

T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))

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NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 1, location 18172 - 84960:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (mal)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

4059062

PKS_AT (904..1203): mal

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 79.2%; Methylmalonyl-CoA: 62.5%; inactive: 62.5%

minowa: Malonyl-CoA

Prediction, score:

Malonyl-CoA: 93.2
Methylmalonyl-CoA: 64.6
Methoxymalonyl-CoA: 59.0
inactive: 44.4
Propionyl-CoA: 37.0
Isobutyryl-CoA: 26.2
2-Methylbutyryl-CoA: 19.5
Ethylmalonyl-CoA: 18.3
CHC-CoA: 15.4
Benzoyl-CoA: 15.3
Acetyl-CoA: 11.7
3-Methylbutyryl-CoA: 11.7
fatty_acid: 11.6
trans-1,2-CPDA: 9.2

scaffold_766 - Region 1 - NRPS,indole

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Location: 1 - 21,585 nt. (total: 21,585 nt) Show pHMM detection rules used

Region on contig edge.

NRPS: cds(Condensation and (AMP-binding or A-OX))
indole: (indsynth or dmat or indole_PTase)

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Predicted core structure(s)

For candidate cluster 1, location 0 - 21585:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (X - X)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

3376542

AMP-binding (29..407): X

nrpys: Val, Leu, Ile, Abu, Ival

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic (Ala, Gly, Val, Leu, Ile, Abu, Ival, Ser, Thr, Hpg, Dhpg, Cys, Pro, Hpr)
Large clusters prediction:: Apolar, aliphatic (Gly, Ala, Val, Leu, Ile, Abu, Ival)
Small clusters prediction:: Aliphatic, branched hydrophobic (Val, Leu, Ile, Abu, Ival)
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: DAGPYGCCAK
Nearest Stachelhaus code(s):: Phe DAGALGACAK (68% 8� match); Trp DAGIVGACAK (56% 8� match)
Stachelhaus code match:: 70% (weak)

AMP-binding (1061..1444): X

nrpys: 6-clTrp

SVM prediction details:

Predicted physicochemical class:: N/A
Large clusters prediction:: N/A
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: DAAMLGGVGK
Nearest Stachelhaus code(s):: 6-clTrp DAAMCGGVAK (44% 8� match)
Stachelhaus code match:: 80% (moderate)

scaffold_767 - Region 1 - terpene

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Location: 1 - 16,783 nt. (total: 16,783 nt) Show pHMM detection rules used

Region on contig edge.

terpene: (Terpene_synth or Terpene_synth_C or phytoene_synt or Lycopene_cycl or terpene_cyclase or NapT7 or fung_ggpps or fung_ggpps2 or trichodiene_synth or TRI5)

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scaffold_77 - Region 1 - NRPS,T1PKS

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Location: 60,152 - 116,591 nt. (total: 56,440 nt) Show pHMM detection rules used

Region on contig edge.

T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))
NRPS: cds(Condensation and (AMP-binding or A-OX))

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NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 1, location 60151 - 116591:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (pk - X)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

4059102

PKS_AT (551..866): pk

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 79.2%; Methylmalonyl-CoA: 66.7%; Ethylmalonyl-CoA: 58.3%

minowa: Methylmalonyl-CoA

Prediction, score:

Methylmalonyl-CoA: 87.8
Methoxymalonyl-CoA: 73.7
Ethylmalonyl-CoA: 64.6
Isobutyryl-CoA: 51.4
Malonyl-CoA: 32.3
Benzoyl-CoA: 31.5
trans-1,2-CPDA: 30.7
Propionyl-CoA: 29.4
fatty_acid: 28.1
2-Methylbutyryl-CoA: 27.6
3-Methylbutyryl-CoA: 17.3
CHC-CoA: 16.5
inactive: 11.1
Acetyl-CoA: 3.3

AMP-binding (3028..3431): X

nrpys: Orn, Lys, Arg

SVM prediction details:

Predicted physicochemical class:: hydrophilic (Arg, Asp, Glu, Asn, Lys, Gln, Orn, Aad)
Large clusters prediction:: Long positively charged side chain (Orn, Lys, Arg)
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: DLAKFGCISK
Nearest Stachelhaus code(s):: MalAc NHDKFGSISK (59% 8� match); Hty DLAFTGCVTK (56% 8� match); 3Me-Glu DLGKTGVINK (53% 8� match); Asp DLTKVGHIGK (50% 8� match); Asn DLTKVGDVSK (47% 8� match)
Stachelhaus code match:: 60% (weak)

scaffold_79 - Region 1 - NRPS,T1PKS

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Location: 48,645 - 115,605 nt. (total: 66,961 nt) Show pHMM detection rules used

Region on contig edge.

NRPS: cds(Condensation and (AMP-binding or A-OX))
T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))

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Predicted core structure(s)

For candidate cluster 1, location 48644 - 115605:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (redmal - Gly)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

4256624

Search NORINE for peptide: strict or relaxed

PKS_AT (545..858): mal

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 79.2%; Methylmalonyl-CoA: 62.5%; Isobutyryl-CoA: 54.2%

minowa: Isobutyryl-CoA

Prediction, score:

Isobutyryl-CoA: 81.8
Methylmalonyl-CoA: 80.2
Methoxymalonyl-CoA: 77.2
Malonyl-CoA: 62.6
Ethylmalonyl-CoA: 39.4
Propionyl-CoA: 38.0
Benzoyl-CoA: 36.6
inactive: 35.1
3-Methylbutyryl-CoA: 33.6
trans-1,2-CPDA: 27.4
2-Methylbutyryl-CoA: 25.1
fatty_acid: 14.1
Acetyl-CoA: 12.7
CHC-CoA: 8.8

AMP-binding (2799..3212): Gly

nrpys: Gly

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic (Ala, Gly, Val, Leu, Ile, Abu, Ival, Ser, Thr, Hpg, Dhpg, Cys, Pro, Hpr)
Large clusters prediction:: N/A
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: DLVYFATVQK
Nearest Stachelhaus code(s):: Gly DLVYFATVQK (85% 8� match)
Stachelhaus code match:: 100% (strong)

scaffold_815 - Region 1 - terpene

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Location: 1 - 19,727 nt. (total: 19,727 nt) Show pHMM detection rules used

Region on contig edge.

terpene: (Terpene_synth or Terpene_synth_C or phytoene_synt or Lycopene_cycl or terpene_cyclase or NapT7 or fung_ggpps or fung_ggpps2 or trichodiene_synth or TRI5)

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scaffold_82 - Region 1 - T1PKS

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Location: 29,308 - 97,607 nt. (total: 68,300 nt) Show pHMM detection rules used

T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))

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Predicted core structure(s)

For candidate cluster 1, location 29307 - 97607:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (mal)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

4247027

PKS_AT (914..1206): mal

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 58.3%; inactive: 54.2%

minowa: Malonyl-CoA

Prediction, score:

Malonyl-CoA: 54.2
Methoxymalonyl-CoA: 50.2
inactive: 46.2
Methylmalonyl-CoA: 42.2
fatty_acid: 30.9
Ethylmalonyl-CoA: 22.6
CHC-CoA: 19.6
Propionyl-CoA: 18.5
trans-1,2-CPDA: 17.3
2-Methylbutyryl-CoA: 17.2
Benzoyl-CoA: 14.8
Isobutyryl-CoA: 14.6
3-Methylbutyryl-CoA: 13.2
Acetyl-CoA: 11.1

scaffold_83 - Region 1 - terpene

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Location: 42,840 - 73,935 nt. (total: 31,096 nt) Show pHMM detection rules used

terpene: (Terpene_synth or Terpene_synth_C or phytoene_synt or Lycopene_cycl or terpene_cyclase or NapT7 or fung_ggpps or fung_ggpps2 or trichodiene_synth or TRI5)

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scaffold_904 - Region 1 - T1PKS

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Location: 1 - 16,139 nt. (total: 16,139 nt) Show pHMM detection rules used

Region on contig edge.

T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))

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Predicted core structure(s)

For candidate cluster 1, location 0 - 16139:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (pk)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

4068855

PKS_AT (553..865): pk

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 75.0%; Methylmalonyl-CoA: 62.5%; Methoxymalonyl-CoA: 58.3%

minowa: Methylmalonyl-CoA

Prediction, score:

Methylmalonyl-CoA: 74.1
Methoxymalonyl-CoA: 68.0
Ethylmalonyl-CoA: 43.9
Isobutyryl-CoA: 37.9
Malonyl-CoA: 31.9
Benzoyl-CoA: 28.1
trans-1,2-CPDA: 26.9
Propionyl-CoA: 20.1
fatty_acid: 19.9
3-Methylbutyryl-CoA: 14.7
CHC-CoA: 14.1
2-Methylbutyryl-CoA: 12.5
inactive: 0.0
Acetyl-CoA: 0.0

scaffold_92 - Region 1 - NRPS-like

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Location: 4,378 - 67,931 nt. (total: 63,554 nt) Show pHMM detection rules used

NRPS-like: cds((PP-binding or NAD_binding_4) and (AMP-binding or A-OX))

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Predicted core structure(s)

For candidate cluster 1, location 4377 - 67931:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (X)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

4250974

AMP-binding (45..378): X

nrpys: Ala, Gly, Val, Leu, Ile, Abu, Ival, Ser, Thr, Hpg, Dhpg, Cys, Pro, Hpr

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic (Ala, Gly, Val, Leu, Ile, Abu, Ival, Ser, Thr, Hpg, Dhpg, Cys, Pro, Hpr)
Large clusters prediction:: N/A
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: HGACGGRFLK
Nearest Stachelhaus code(s):
Stachelhaus code match:: 0% (weak)

scaffold_933 - Region 1 - NRPS

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Location: 1 - 15,144 nt. (total: 15,144 nt) Show pHMM detection rules used

Region on contig edge.

NRPS: cds(Condensation and (AMP-binding or A-OX))

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Predicted core structure(s)

For candidate cluster 1, location 0 - 15144:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (Phe)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

4068962

Search NORINE for peptide: strict or relaxed

AMP-binding (623..1007): Phe

nrpys: Phe

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aromatic (Phe, Tyr, diOH-Bz, Ph-Gly, bOH-Tyr)
Large clusters prediction:: Aromatic side chain (Phe, Trp, Ph-Gly, Tyr, bOH-Tyr)
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: DGHIYVMCGK
Nearest Stachelhaus code(s):: Phe DGHIYVMCGK (91% 8� match)
Stachelhaus code match:: 100% (strong)

scaffold_945 - Region 1 - T1PKS

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Location: 1 - 14,461 nt. (total: 14,461 nt) Show pHMM detection rules used

Region on contig edge.

T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))

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Predicted core structure(s)

For candidate cluster 1, location 0 - 14461:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (pk)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

4039593

PKS_AT (541..849): pk

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 87.5%; Methylmalonyl-CoA: 66.7%; Ethylmalonyl-CoA: 62.5%

minowa: Methylmalonyl-CoA

Prediction, score:

Methylmalonyl-CoA: 99.3
Methoxymalonyl-CoA: 88.5
Malonyl-CoA: 72.7
Ethylmalonyl-CoA: 69.3
Isobutyryl-CoA: 59.7
2-Methylbutyryl-CoA: 48.0
Propionyl-CoA: 38.7
Benzoyl-CoA: 34.8
inactive: 34.5
trans-1,2-CPDA: 25.9
3-Methylbutyryl-CoA: 19.3
fatty_acid: 13.1
CHC-CoA: 0.0
Acetyl-CoA: 0.0

scaffold_961 - Region 1 - terpene

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Location: 1 - 13,803 nt. (total: 13,803 nt) Show pHMM detection rules used

Region on contig edge.

terpene: (Terpene_synth or Terpene_synth_C or phytoene_synt or Lycopene_cycl or terpene_cyclase or NapT7 or fung_ggpps or fung_ggpps2 or trichodiene_synth or TRI5)

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No matches found.

scaffold_97 - Region 1 - NRPS-like

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Location: 55,376 - 108,861 nt. (total: 53,486 nt) Show pHMM detection rules used

Region on contig edge.

NRPS-like: cds((PP-binding or NAD_binding_4) and (AMP-binding or A-OX))

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No matches found.

NRPS/PKS monomers

NRPS/PKS monomer predictions

4059692

AMP-binding (36..426): X

nrpys: Ala, Gly, Val, Leu, Ile, Abu, Ival, Ser, Thr, Hpg, Dhpg, Cys, Pro, Hpr

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic (Ala, Gly, Val, Leu, Ile, Abu, Ival, Ser, Thr, Hpg, Dhpg, Cys, Pro, Hpr)
Large clusters prediction:: N/A
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: ---VMAFILK
Nearest Stachelhaus code(s):
Stachelhaus code match:: 0% (weak)

scaffold_973 - Region 1 - T1PKS

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Location: 1 - 13,354 nt. (total: 13,354 nt) Show pHMM detection rules used

Region on contig edge.

T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))

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core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

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Gene details

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Gene overview

NRPS/PKS domains

KnownClusterBlast

Gene/CDS overview

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Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

Detailed domain annotation

Selected features only

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Similar known gene clusters from MIBiG 3.1

No matches found.

NRPS/PKS monomers

NRPS/PKS monomer predictions

4054895

PKS_AT (434..670): pk

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 58.3%

minowa: Methylmalonyl-CoA

Prediction, score:

Methylmalonyl-CoA: 46.6
Methoxymalonyl-CoA: 41.0
Malonyl-CoA: 19.9
Ethylmalonyl-CoA: 18.1
Isobutyryl-CoA: 17.0
Propionyl-CoA: 16.8
fatty_acid: 15.8
CHC-CoA: 13.9
2-Methylbutyryl-CoA: 10.7
trans-1,2-CPDA: 10.5
Benzoyl-CoA: 8.2
3-Methylbutyryl-CoA: 5.0
inactive: 0.0
Acetyl-CoA: 0.0