Lobaria pulmonaria Scotland extracted metagenome v1.0

Identified secondary metabolite regions using strictness 'relaxed'

scaffold_100

Region	Type	From	To	Most similar known cluster		Similarity
Region 3.1	NRPS,indole	70,955	116,626

scaffold_106

Region	Type	From	To	Most similar known cluster		Similarity
Region 69.1	terpene	80,082	111,763

scaffold_108

Region	Type	From	To	Most similar known cluster		Similarity
Region 91.1	NRPS-like	55,641	111,493

scaffold_113

Region	Type	From	To	Most similar known cluster		Similarity
Region 147.1	fungal-RiPP-like	12,149	103,455	BU-4704/xanthocillin-X monomethylether/melanocin E/melanocin F/fumiformamide	Other	28%

scaffold_114

Region	Type	From	To	Most similar known cluster		Similarity
Region 158.1	terpene	60,888	92,515

scaffold_115

Region	Type	From	To	Most similar known cluster		Similarity
Region 169.1	T1PKS,NRPS	40,042	110,636	flavichalasine F/flavichalasine G/aspochalasin C/aspochalasin E/aspochalasin M/TMC-169/aspergillin PZ	Polyketide+NRP	63%

scaffold_129

Region	Type	From	To	Most similar known cluster		Similarity
Region 224.1	fungal-RiPP-like	33,731	104,639

scaffold_133

Region	Type	From	To	Most similar known cluster		Similarity
Region 229.1	NRPS,T1PKS	46,460	102,853

scaffold_147

Region	Type	From	To	Most similar known cluster		Similarity
Region 244.1	T1PKS	15,254	84,052

scaffold_156

Region	Type	From	To	Most similar known cluster		Similarity
Region 254.1	fungal-RiPP-like	1	79,336

scaffold_164

Region	Type	From	To	Most similar known cluster		Similarity
Region 263.1	NRPS-like	6,722	70,123

scaffold_169

Region	Type	From	To	Most similar known cluster		Similarity
Region 268.1	T1PKS	46,937	85,682

scaffold_172

Region	Type	From	To	Most similar known cluster		Similarity
Region 272.1	fungal-RiPP-like	26,160	84,962

scaffold_173

Region	Type	From	To	Most similar known cluster		Similarity
Region 273.1	terpene	53,880	84,591

scaffold_193

Region	Type	From	To	Most similar known cluster		Similarity
Region 295.1	T1PKS	1	62,352	waikikiamide A/waikikiamide B/waikikiamide C/(+)-semivioxanthin/semivioxanthin	Polyketide	36%

scaffold_200

Region	Type	From	To	Most similar known cluster		Similarity
Region 304.1	terpene	211	31,437

scaffold_206

Region	Type	From	To	Most similar known cluster		Similarity
Region 310.1	fungal-RiPP-like	1	76,942

scaffold_209

Region	Type	From	To	Most similar known cluster		Similarity
Region 313.1	fungal-RiPP-like	164	76,607

scaffold_21

Region	Type	From	To	Most similar known cluster		Similarity
Region 314.1	fungal-RiPP-like	17,578	111,109

scaffold_211

Region	Type	From	To	Most similar known cluster		Similarity
Region 316.1	fungal-RiPP-like	1	57,640

scaffold_222

Region	Type	From	To	Most similar known cluster		Similarity
Region 328.1	T1PKS	1	59,745

scaffold_228

Region	Type	From	To	Most similar known cluster		Similarity
Region 334.1	NRPS	14,601	71,618

scaffold_239

Region	Type	From	To	Most similar known cluster		Similarity
Region 346.1	fungal-RiPP-like	1	69,471

scaffold_246

Region	Type	From	To	Most similar known cluster		Similarity
Region 354.1	fungal-RiPP-like	3,265	68,932

scaffold_25

Region	Type	From	To	Most similar known cluster		Similarity
Region 358.1	T1PKS	1	32,586

scaffold_252

Region	Type	From	To	Most similar known cluster		Similarity
Region 361.1	fungal-RiPP-like	2,784	67,220

scaffold_269

Region	Type	From	To	Most similar known cluster		Similarity
Region 379.1	fungal-RiPP-like	1	46,358

scaffold_295

Region	Type	From	To	Most similar known cluster		Similarity
Region 408.1	T1PKS,NRPS-like	1	51,650	2,4-dihydroxy-5,6-dimethyl benzaldehyde	Polyketide	28%

scaffold_296

Region	Type	From	To	Most similar known cluster		Similarity
Region 409.1	T1PKS	1	41,910	1,3,6,8-tetrahydroxynaphthalene	Polyketide	100%

scaffold_321

Region	Type	From	To	Most similar known cluster		Similarity
Region 438.1	T1PKS	25	54,382	ochratoxin A	NRP+Polyketide	100%

scaffold_33

Region	Type	From	To	Most similar known cluster		Similarity
Region 447.1	NRPS	124,238	200,998	fellutamide B	NRP	42%

scaffold_335

Region	Type	From	To	Most similar known cluster		Similarity
Region 453.1	terpene	1	22,983

scaffold_338

Region	Type	From	To	Most similar known cluster		Similarity
Region 456.1	T1PKS	5,706	53,141

scaffold_339

Region	Type	From	To	Most similar known cluster		Similarity
Region 457.1	NRPS-like	1	51,229

scaffold_345

Region	Type	From	To	Most similar known cluster		Similarity
Region 464.1	NRPS-like	1	48,869

scaffold_352

Region	Type	From	To	Most similar known cluster		Similarity
Region 472.1	T1PKS	1	49,090	oxyjavanicin	Polyketide	25%

scaffold_357

Region	Type	From	To	Most similar known cluster		Similarity
Region 477.1	fungal-RiPP-like	1	50,762

scaffold_364

Region	Type	From	To	Most similar known cluster		Similarity
Region 485.1	NRPS-like	11,091	49,889

scaffold_365

Region	Type	From	To	Most similar known cluster		Similarity
Region 486.1	terpene	1	21,801

scaffold_37

Region	Type	From	To	Most similar known cluster		Similarity
Region 491.1	fungal-RiPP-like	105,648	194,000

scaffold_372

Region	Type	From	To	Most similar known cluster		Similarity
Region 494.1	terpene	4,400	35,626

scaffold_379

Region	Type	From	To	Most similar known cluster		Similarity
Region 501.1	T1PKS	1	47,899

scaffold_391

Region	Type	From	To	Most similar known cluster		Similarity
Region 515.1	T1PKS,terpene	1	46,927

scaffold_40

Region	Type	From	To	Most similar known cluster		Similarity
Region 525.1	terpene	168,461	189,691	squalestatin S1	Terpene	40%

scaffold_404

Region	Type	From	To	Most similar known cluster		Similarity
Region 530.1	indole	1	25,282

scaffold_426

Region	Type	From	To	Most similar known cluster		Similarity
Region 554.1	indole	21,489	41,976	biscognienyne B/eutypinic acid/compound 3/4-hydroxy-3-prenylbenzoic acid/prenylhydroquinone/compound 15/compound 8/compound 7/compound 6/compound 11/compound 12/pestalodiol E	Other	63%

scaffold_429

Region	Type	From	To	Most similar known cluster		Similarity
Region 557.1	NRPS	1	41,729

scaffold_439

Region	Type	From	To	Most similar known cluster		Similarity
Region 568.1	T1PKS	1	40,622	1,3,6,8-tetrahydroxynaphthalene	Polyketide	100%

scaffold_440

Region	Type	From	To	Most similar known cluster		Similarity
Region 570.1	NRPS-like	3,504	40,619	aspulvinone H/aspulvinone B1	NRP	100%

scaffold_488

Region	Type	From	To	Most similar known cluster		Similarity
Region 622.1	T1PKS	671	35,980	terreic acid	Polyketide	33%

scaffold_49

Region	Type	From	To	Most similar known cluster		Similarity
Region 624.1	T1PKS	43,309	111,859

scaffold_491

Region	Type	From	To	Most similar known cluster		Similarity
Region 626.1	T1PKS	1	35,846

scaffold_5

Region	Type	From	To	Most similar known cluster		Similarity
Region 635.1	T1PKS	389,143	439,479	4-oxomacrophorin A/macrophorin A/5'-epimacrophorin B	Terpene	72%

scaffold_504

Region	Type	From	To	Most similar known cluster		Similarity
Region 641.1	T1PKS	1	34,482

scaffold_509

Region	Type	From	To	Most similar known cluster		Similarity
Region 646.1	NRPS-like	1	33,484

scaffold_51

Region	Type	From	To	Most similar known cluster		Similarity
Region 647.1	NRPS-like	32,522	84,886
Region 647.2	NRPS,T1PKS	114,075	163,148

scaffold_517

Region	Type	From	To	Most similar known cluster		Similarity
Region 655.1	NRPS	1	32,852

scaffold_523

Region	Type	From	To	Most similar known cluster		Similarity
Region 662.1	T1PKS	1	31,852	naphthopyrone	Polyketide	100%

scaffold_528

Region	Type	From	To	Most similar known cluster		Similarity
Region 667.1	T1PKS	1	31,665

scaffold_554

Region	Type	From	To	Most similar known cluster		Similarity
Region 696.1	terpene	1	22,294

scaffold_56

Region	Type	From	To	Most similar known cluster		Similarity
Region 702.1	T1PKS	1	61,470	ankaflavin/monascin/rubropunctatine/monascorubrin	Polyketide:Iterative type I polyketide	20%
Region 702.2	NRPS-like	87,692	151,689

scaffold_560

Region	Type	From	To	Most similar known cluster		Similarity
Region 703.1	T1PKS	1	29,164

scaffold_575

Region	Type	From	To	Most similar known cluster		Similarity
Region 719.1	T1PKS	1	28,454

scaffold_587

Region	Type	From	To	Most similar known cluster		Similarity
Region 732.1	terpene	5,201	27,656

scaffold_593

Region	Type	From	To	Most similar known cluster		Similarity
Region 739.1	NRPS-like	1	27,124

scaffold_596

Region	Type	From	To	Most similar known cluster		Similarity
Region 742.1	terpene	1	26,792

scaffold_598

Region	Type	From	To	Most similar known cluster		Similarity
Region 744.1	NRPS,NRP-metallophore	1	26,662

scaffold_60

Region	Type	From	To	Most similar known cluster		Similarity
Region 747.1	NRPS	1	40,703

scaffold_618

Region	Type	From	To	Most similar known cluster		Similarity
Region 767.1	terpene	1	24,977

scaffold_62

Region	Type	From	To	Most similar known cluster		Similarity
Region 769.1	NRPS-like	1	39,861

scaffold_63

Region	Type	From	To	Most similar known cluster		Similarity
Region 780.1	fungal-RiPP-like	63,122	145,664

scaffold_66

Region	Type	From	To	Most similar known cluster		Similarity
Region 813.1	T1PKS,NRPS-like	1	67,017	xenolozoyenone	NRP:Lipopeptide+Polyketide:Iterative type I polyketide	100%

scaffold_69

Region	Type	From	To	Most similar known cluster		Similarity
Region 846.1	terpene,T1PKS	14,509	100,585

scaffold_7

Region	Type	From	To	Most similar known cluster		Similarity
Region 857.1	fungal-RiPP-like	1	64,252

scaffold_70

Region	Type	From	To	Most similar known cluster		Similarity
Region 858.1	indole	86,682	117,785

scaffold_711

Region	Type	From	To	Most similar known cluster		Similarity
Region 871.1	terpene	1	20,700

scaffold_79

Region	Type	From	To	Most similar known cluster		Similarity
Region 957.1	fungal-RiPP-like	32,469	123,601

scaffold_804

Region	Type	From	To	Most similar known cluster		Similarity
Region 974.1	T1PKS	1	16,570

scaffold_81

Region	Type	From	To	Most similar known cluster		Similarity
Region 980.1	T1PKS	62,382	128,945	usnic acid	Polyketide	26%

scaffold_813

Region	Type	From	To	Most similar known cluster		Similarity
Region 984.1	fungal-RiPP-like	1	16,261

scaffold_817

Region	Type	From	To	Most similar known cluster		Similarity
Region 988.1	T1PKS	1	16,101	betaenone A/betaenone B/betaenone C	Polyketide	25%

scaffold_84

Region	Type	From	To	Most similar known cluster		Similarity
Region 1013.1	fungal-RiPP-like	10,142	123,891

scaffold_86

Region	Type	From	To	Most similar known cluster		Similarity
Region 1035.1	NRPS,T1PKS	36,807	125,685	leucinostatin A/leucinostatin B	NRP+Polyketide	10%

scaffold_865

Region	Type	From	To	Most similar known cluster		Similarity
Region 1041.1	NRPS	1	13,800

scaffold_87

Region	Type	From	To	Most similar known cluster		Similarity
Region 1046.1	fungal-RiPP-like	1	58,400

scaffold_88

Region	Type	From	To	Most similar known cluster		Similarity
Region 1057.1	T1PKS	60,803	124,025	monascorubrin	Polyketide	100%

scaffold_892

Region	Type	From	To	Most similar known cluster		Similarity
Region 1071.1	T1PKS	1	12,645	3'-methoxy-1,2-dehydropenicillide/pestalotiollide B/pestalotiollide C/1,2-dehydropenicillide/3-methoxy-1,2-dehydropenicillide/1,2-epoxy-3,4-didehydropenicillide	Polyketide	15%

scaffold_91

Region	Type	From	To	Most similar known cluster		Similarity
Region 1091.1	indole	71,056	102,258

scaffold_94

Region	Type	From	To	Most similar known cluster		Similarity
Region 1124.1	T1PKS	40,049	106,403

scaffold_959

Region	Type	From	To	Most similar known cluster		Similarity
Region 1145.1	fungal-RiPP-like	1	10,251

scaffold_96

Region	Type	From	To	Most similar known cluster		Similarity
Region 1146.1	NRPS-like	47,318	110,669

scaffold_98

Region	Type	From	To	Most similar known cluster		Similarity
Region 1168.1	T1PKS	13,509	81,836	4-epi-15-epi-brefeldin A	Polyketide:Iterative type I polyketide	30%

No secondary metabolite regions were found in these records:: scaffold_1; scaffold_10; scaffold_1000; scaffold_1001; scaffold_1002; scaffold_1003; scaffold_1004; scaffold_1005; scaffold_1006; scaffold_1007; scaffold_1008; scaffold_1009; scaffold_101; scaffold_1010; scaffold_1011; scaffold_1012; scaffold_1013; scaffold_1014; scaffold_1015; scaffold_1016; scaffold_1017; scaffold_1018; scaffold_1019; scaffold_102; scaffold_1020; scaffold_1021; scaffold_1022; scaffold_1023; scaffold_1024; scaffold_1025; scaffold_1026; scaffold_1027; scaffold_1028; scaffold_1029; scaffold_103; scaffold_1030; scaffold_1031; scaffold_1032; scaffold_1033; scaffold_1034; scaffold_1035; scaffold_1036; scaffold_1037; scaffold_1038; scaffold_1039; scaffold_104; scaffold_1040; scaffold_1041; scaffold_1042; scaffold_1043; scaffold_1044; scaffold_1045; scaffold_1046; scaffold_1047; scaffold_1048; scaffold_1049; scaffold_105; scaffold_1050; scaffold_1051; scaffold_1052; scaffold_1053; scaffold_1054; scaffold_1055; scaffold_1056; scaffold_1057; scaffold_1058; scaffold_1059; scaffold_1060; scaffold_1061; scaffold_1062; scaffold_1063; scaffold_1064; scaffold_1065; scaffold_1066; scaffold_1067; scaffold_1068; scaffold_1069; scaffold_107; scaffold_1070; scaffold_1071; scaffold_1072; scaffold_1073; scaffold_1074; scaffold_1075; scaffold_1076; scaffold_1077; scaffold_1078; scaffold_1079; scaffold_1080; scaffold_1081; scaffold_1082; scaffold_1083; scaffold_1084; scaffold_1085; scaffold_1086; scaffold_1087; scaffold_1088; scaffold_1089; scaffold_109; scaffold_1090; scaffold_1091; scaffold_1092; scaffold_1093; scaffold_1094; scaffold_1095; scaffold_1096; scaffold_1097; scaffold_1098; scaffold_1099; scaffold_11; scaffold_110; scaffold_1100; scaffold_1101; scaffold_1102; scaffold_1103; scaffold_1104; scaffold_1105; scaffold_1106; scaffold_1107; scaffold_1108; scaffold_1109; scaffold_111; scaffold_1110; scaffold_1111; scaffold_1112; scaffold_1113; scaffold_1114; scaffold_1115; scaffold_1116; scaffold_1117; scaffold_1118; scaffold_1119; scaffold_112; scaffold_1120; scaffold_1121; scaffold_1122; scaffold_1123; scaffold_1124; scaffold_1125; scaffold_1126; scaffold_1127; scaffold_1128; scaffold_1129; scaffold_1130; scaffold_1131; scaffold_1132; scaffold_1133; scaffold_1134; scaffold_1135; scaffold_1136; scaffold_1137; scaffold_1138; scaffold_1139; scaffold_1140; scaffold_1141; scaffold_1142; scaffold_1143; scaffold_1144; scaffold_1145; scaffold_1146; scaffold_1147; scaffold_1148; scaffold_1149; scaffold_1150; scaffold_1151; scaffold_1152; scaffold_1153; scaffold_1154; scaffold_1155; scaffold_1156; scaffold_1157; scaffold_1158; scaffold_1159; scaffold_116; scaffold_1160; scaffold_1161; scaffold_1162; scaffold_1163; scaffold_1164; scaffold_1165; scaffold_1166; scaffold_1167; scaffold_1168; scaffold_1169; scaffold_117; scaffold_1170; scaffold_1171; scaffold_1172; scaffold_1173; scaffold_1174; scaffold_1175; scaffold_1176; scaffold_1177; scaffold_1178; scaffold_1179; scaffold_118; scaffold_1180; scaffold_1181; scaffold_1182; scaffold_1183; scaffold_1184; scaffold_1185; scaffold_1186; scaffold_1187; scaffold_1188; scaffold_1189; scaffold_119; scaffold_12; scaffold_120; scaffold_121; scaffold_122; scaffold_123; scaffold_124; scaffold_125; scaffold_126; scaffold_127; scaffold_128; scaffold_13; scaffold_130; scaffold_131; scaffold_132; scaffold_134; scaffold_135; scaffold_136; scaffold_137; scaffold_138; scaffold_139; scaffold_14; scaffold_140; scaffold_141; scaffold_142; scaffold_143; scaffold_144; scaffold_145; scaffold_146; scaffold_148; scaffold_149; scaffold_15; scaffold_150; scaffold_151; scaffold_152; scaffold_153; scaffold_154; scaffold_155; scaffold_157; scaffold_158; scaffold_159; scaffold_16; scaffold_160; scaffold_161; scaffold_162; scaffold_163; scaffold_165; scaffold_166; scaffold_167; scaffold_168; scaffold_17; scaffold_170; scaffold_171; scaffold_174; scaffold_175; scaffold_176; scaffold_177; scaffold_178; scaffold_179; scaffold_18; scaffold_180; scaffold_181; scaffold_182; scaffold_183; scaffold_184; scaffold_185; scaffold_186; scaffold_187; scaffold_188; scaffold_189; scaffold_19; scaffold_190; scaffold_191; scaffold_192; scaffold_194; scaffold_195; scaffold_196; scaffold_197; scaffold_198; scaffold_199; scaffold_2; scaffold_20; scaffold_201; scaffold_202; scaffold_203; scaffold_204; scaffold_205; scaffold_207; scaffold_208; scaffold_210; scaffold_212; scaffold_213; scaffold_214; scaffold_215; scaffold_216; scaffold_217; scaffold_218; scaffold_219; scaffold_22; scaffold_220; scaffold_221; scaffold_223; scaffold_224; scaffold_225; scaffold_226; scaffold_227; scaffold_229; scaffold_23; scaffold_230; scaffold_231; scaffold_232; scaffold_233; scaffold_234; scaffold_235; scaffold_236; scaffold_237; scaffold_238; scaffold_24; scaffold_240; scaffold_241; scaffold_242; scaffold_243; scaffold_244; scaffold_245; scaffold_247; scaffold_248; scaffold_249; scaffold_250; scaffold_251; scaffold_253; scaffold_254; scaffold_255; scaffold_256; scaffold_257; scaffold_258; scaffold_259; scaffold_26; scaffold_260; scaffold_261; scaffold_262; scaffold_263; scaffold_264; scaffold_265; scaffold_266; scaffold_267; scaffold_268; scaffold_27; scaffold_270; scaffold_271; scaffold_272; scaffold_273; scaffold_274; scaffold_275; scaffold_276; scaffold_277; scaffold_278; scaffold_279; scaffold_28; scaffold_280; scaffold_281; scaffold_282; scaffold_283; scaffold_284; scaffold_285; scaffold_286; scaffold_287; scaffold_288; scaffold_289; scaffold_29; scaffold_290; scaffold_291; scaffold_292; scaffold_293; scaffold_294; scaffold_297; scaffold_298; scaffold_299; scaffold_3; scaffold_30; scaffold_300; scaffold_301; scaffold_302; scaffold_303; scaffold_304; scaffold_305; scaffold_306; scaffold_307; scaffold_308; scaffold_309; scaffold_31; scaffold_310; scaffold_311; scaffold_312; scaffold_313; scaffold_314; scaffold_315; scaffold_316; scaffold_317; scaffold_318; scaffold_319; scaffold_32; scaffold_320; scaffold_322; scaffold_323; scaffold_324; scaffold_325; scaffold_326; scaffold_327; scaffold_328; scaffold_329; scaffold_330; scaffold_331; scaffold_332; scaffold_333; scaffold_334; scaffold_336; scaffold_337; scaffold_34; scaffold_340; scaffold_341; scaffold_342; scaffold_343; scaffold_344; scaffold_346; scaffold_347; scaffold_348; scaffold_349; scaffold_35; scaffold_350; scaffold_351; scaffold_353; scaffold_354; scaffold_355; scaffold_356; scaffold_358; scaffold_359; scaffold_36; scaffold_360; scaffold_361; scaffold_362; scaffold_363; scaffold_366; scaffold_367; scaffold_368; scaffold_369; scaffold_370; scaffold_371; scaffold_373; scaffold_374; scaffold_375; scaffold_376; scaffold_377; scaffold_378; scaffold_38; scaffold_380; scaffold_381; scaffold_382; scaffold_383; scaffold_384; scaffold_385; scaffold_386; scaffold_387; scaffold_388; scaffold_389; scaffold_39; scaffold_390; scaffold_392; scaffold_393; scaffold_394; scaffold_395; scaffold_396; scaffold_397; scaffold_398; scaffold_399; scaffold_4; scaffold_400; scaffold_401; scaffold_402; scaffold_403; scaffold_405; scaffold_406; scaffold_407; scaffold_408; scaffold_409; scaffold_41; scaffold_410; scaffold_411; scaffold_412; scaffold_413; scaffold_414; scaffold_415; scaffold_416; scaffold_417; scaffold_418; scaffold_419; scaffold_42; scaffold_420; scaffold_421; scaffold_422; scaffold_423; scaffold_424; scaffold_425; scaffold_427; scaffold_428; scaffold_43; scaffold_430; scaffold_431; scaffold_432; scaffold_433; scaffold_434; scaffold_435; scaffold_436; scaffold_437; scaffold_438; scaffold_44; scaffold_441; scaffold_442; scaffold_443; scaffold_444; scaffold_445; scaffold_446; scaffold_447; scaffold_448; scaffold_449; scaffold_45; scaffold_450; scaffold_451; scaffold_452; scaffold_453; scaffold_454; scaffold_455; scaffold_456; scaffold_457; scaffold_458; scaffold_459; scaffold_46; scaffold_460; scaffold_461; scaffold_462; scaffold_463; scaffold_464; scaffold_465; scaffold_466; scaffold_467; scaffold_468; scaffold_469; scaffold_47; scaffold_470; scaffold_471; scaffold_472; scaffold_473; scaffold_474; scaffold_475; scaffold_476; scaffold_477; scaffold_478; scaffold_479; scaffold_48; scaffold_480; scaffold_481; scaffold_482; scaffold_483; scaffold_484; scaffold_485; scaffold_486; scaffold_487; scaffold_489; scaffold_490; scaffold_492; scaffold_493; scaffold_494; scaffold_495; scaffold_496; scaffold_497; scaffold_498; scaffold_499; scaffold_50; scaffold_500; scaffold_501; scaffold_502; scaffold_503; scaffold_505; scaffold_506; scaffold_507; scaffold_508; scaffold_510; scaffold_511; scaffold_512; scaffold_513; scaffold_514; scaffold_515; scaffold_516; scaffold_518; scaffold_519; scaffold_52; scaffold_520; scaffold_521; scaffold_522; scaffold_524; scaffold_525; scaffold_526; scaffold_527; scaffold_529; scaffold_53; scaffold_530; scaffold_531; scaffold_532; scaffold_533; scaffold_534; scaffold_535; scaffold_536; scaffold_537; scaffold_538; scaffold_539; scaffold_54; scaffold_540; scaffold_541; scaffold_542; scaffold_543; scaffold_544; scaffold_545; scaffold_546; scaffold_547; scaffold_548; scaffold_549; scaffold_55; scaffold_550; scaffold_551; scaffold_552; scaffold_553; scaffold_555; scaffold_556; scaffold_557; scaffold_558; scaffold_559; scaffold_561; scaffold_562; scaffold_563; scaffold_564; scaffold_565; scaffold_566; scaffold_567; scaffold_568; scaffold_569; scaffold_57; scaffold_570; scaffold_571; scaffold_572; scaffold_573; scaffold_574; scaffold_576; scaffold_577; scaffold_578; scaffold_579; scaffold_58; scaffold_580; scaffold_581; scaffold_582; scaffold_583; scaffold_584; scaffold_585; scaffold_586; scaffold_588; scaffold_589; scaffold_59; scaffold_590; scaffold_591; scaffold_592; scaffold_594; scaffold_595; scaffold_597; scaffold_599; scaffold_6; scaffold_600; scaffold_601; scaffold_602; scaffold_603; scaffold_604; scaffold_605; scaffold_606; scaffold_607; scaffold_608; scaffold_609; scaffold_61; scaffold_610; scaffold_611; scaffold_612; scaffold_613; scaffold_614; scaffold_615; scaffold_616; scaffold_617; scaffold_619; scaffold_620; scaffold_621; scaffold_622; scaffold_623; scaffold_624; scaffold_625; scaffold_626; scaffold_627; scaffold_628; scaffold_629; scaffold_630; scaffold_631; scaffold_632; scaffold_633; scaffold_634; scaffold_635; scaffold_636; scaffold_637; scaffold_638; scaffold_639; scaffold_64; scaffold_640; scaffold_641; scaffold_642; scaffold_643; scaffold_644; scaffold_645; scaffold_646; scaffold_647; scaffold_648; scaffold_649; scaffold_65; scaffold_650; scaffold_651; scaffold_652; scaffold_653; scaffold_654; scaffold_655; scaffold_656; scaffold_657; scaffold_658; scaffold_659; scaffold_660; scaffold_661; scaffold_662; scaffold_663; scaffold_664; scaffold_665; scaffold_666; scaffold_667; scaffold_668; scaffold_669; scaffold_67; scaffold_670; scaffold_671; scaffold_672; scaffold_673; scaffold_674; scaffold_675; scaffold_676; scaffold_677; scaffold_678; scaffold_679; scaffold_68; scaffold_680; scaffold_681; scaffold_682; scaffold_683; scaffold_684; scaffold_685; scaffold_686; scaffold_687; scaffold_688; scaffold_689; scaffold_690; scaffold_691; scaffold_692; scaffold_693; scaffold_694; scaffold_695; scaffold_696; scaffold_697; scaffold_698; scaffold_699; scaffold_700; scaffold_701; scaffold_702; scaffold_703; scaffold_704; scaffold_705; scaffold_706; scaffold_707; scaffold_708; scaffold_709; scaffold_71; scaffold_710; scaffold_712; scaffold_713; scaffold_714; scaffold_715; scaffold_716; scaffold_717; scaffold_718; scaffold_719; scaffold_72; scaffold_720; scaffold_721; scaffold_722; scaffold_723; scaffold_724; scaffold_725; scaffold_726; scaffold_727; scaffold_728; scaffold_729; scaffold_73; scaffold_730; scaffold_731; scaffold_732; scaffold_733; scaffold_734; scaffold_735; scaffold_736; scaffold_737; scaffold_738; scaffold_739; scaffold_74; scaffold_740; scaffold_741; scaffold_742; scaffold_743; scaffold_744; scaffold_745; scaffold_746; scaffold_747; scaffold_748; scaffold_749; scaffold_75; scaffold_750; scaffold_751; scaffold_752; scaffold_753; scaffold_754; scaffold_755; scaffold_756; scaffold_757; scaffold_758; scaffold_759; scaffold_76; scaffold_760; scaffold_761; scaffold_762; scaffold_763; scaffold_764; scaffold_765; scaffold_766; scaffold_767; scaffold_768; scaffold_769; scaffold_77; scaffold_770; scaffold_771; scaffold_772; scaffold_773; scaffold_774; scaffold_775; scaffold_776; scaffold_777; scaffold_778; scaffold_779; scaffold_78; scaffold_780; scaffold_781; scaffold_782; scaffold_783; scaffold_784; scaffold_785; scaffold_786; scaffold_787; scaffold_788; scaffold_789; scaffold_790; scaffold_791; scaffold_792; scaffold_793; scaffold_794; scaffold_795; scaffold_796; scaffold_797; scaffold_798; scaffold_799; scaffold_8; scaffold_80; scaffold_800; scaffold_801; scaffold_802; scaffold_803; scaffold_805; scaffold_806; scaffold_807; scaffold_808; scaffold_809; scaffold_810; scaffold_811; scaffold_812; scaffold_814; scaffold_815; scaffold_816; scaffold_818; scaffold_819; scaffold_82; scaffold_820; scaffold_821; scaffold_822; scaffold_823; scaffold_824; scaffold_825; scaffold_826; scaffold_827; scaffold_828; scaffold_829; scaffold_83; scaffold_830; scaffold_831; scaffold_832; scaffold_833; scaffold_834; scaffold_835; scaffold_836; scaffold_837; scaffold_838; scaffold_839; scaffold_840; scaffold_841; scaffold_842; scaffold_843; scaffold_844; scaffold_845; scaffold_846; scaffold_847; scaffold_848; scaffold_849; scaffold_85; scaffold_850; scaffold_851; scaffold_852; scaffold_853; scaffold_854; scaffold_855; scaffold_856; scaffold_857; scaffold_858; scaffold_859; scaffold_860; scaffold_861; scaffold_862; scaffold_863; scaffold_864; scaffold_866; scaffold_867; scaffold_868; scaffold_869; scaffold_870; scaffold_871; scaffold_872; scaffold_873; scaffold_874; scaffold_875; scaffold_876; scaffold_877; scaffold_878; scaffold_879; scaffold_880; scaffold_881; scaffold_882; scaffold_883; scaffold_884; scaffold_885; scaffold_886; scaffold_887; scaffold_888; scaffold_889; scaffold_89; scaffold_890; scaffold_891; scaffold_893; scaffold_894; scaffold_895; scaffold_896; scaffold_897; scaffold_898; scaffold_899; scaffold_9; scaffold_90; scaffold_900; scaffold_901; scaffold_902; scaffold_903; scaffold_904; scaffold_905; scaffold_906; scaffold_907; scaffold_908; scaffold_909; scaffold_910; scaffold_911; scaffold_912; scaffold_913; scaffold_914; scaffold_915; scaffold_916; scaffold_917; scaffold_918; scaffold_919; scaffold_92; scaffold_920; scaffold_921; scaffold_922; scaffold_923; scaffold_924; scaffold_925; scaffold_926; scaffold_927; scaffold_928; scaffold_929; scaffold_93; scaffold_930; scaffold_931; scaffold_932; scaffold_933; scaffold_934; scaffold_935; scaffold_936; scaffold_937; scaffold_938; scaffold_939; scaffold_940; scaffold_941; scaffold_942; scaffold_943; scaffold_944; scaffold_945; scaffold_946; scaffold_947; scaffold_948; scaffold_949; scaffold_95; scaffold_950; scaffold_951; scaffold_952; scaffold_953; scaffold_954; scaffold_955; scaffold_956; scaffold_957; scaffold_958; scaffold_960; scaffold_961; scaffold_962; scaffold_963; scaffold_964; scaffold_965; scaffold_966; scaffold_967; scaffold_968; scaffold_969; scaffold_97; scaffold_970; scaffold_971; scaffold_972; scaffold_973; scaffold_974; scaffold_975; scaffold_976; scaffold_977; scaffold_978; scaffold_979; scaffold_980; scaffold_981; scaffold_982; scaffold_983; scaffold_984; scaffold_985; scaffold_986; scaffold_987; scaffold_988; scaffold_989; scaffold_99; scaffold_990; scaffold_991; scaffold_992; scaffold_993; scaffold_994; scaffold_995; scaffold_996; scaffold_997; scaffold_998; scaffold_999

Compact view

scaffold_100 - Region 1 - NRPS,indole

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Location: 70,955 - 116,626 nt. (total: 45,672 nt) Show pHMM detection rules used

Region on contig edge.

NRPS: cds(Condensation and (AMP-binding or A-OX))
indole: (indsynth or dmat or indole_PTase)

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Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

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NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 1, location 70954 - 116626:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (X - X)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

2107527

AMP-binding (29..407): X

nrpys: Val, Leu, Ile, Abu, Ival

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic (Ala, Gly, Val, Leu, Ile, Abu, Ival, Ser, Thr, Hpg, Dhpg, Cys, Pro, Hpr)
Large clusters prediction:: Apolar, aliphatic (Gly, Ala, Val, Leu, Ile, Abu, Ival)
Small clusters prediction:: Aliphatic, branched hydrophobic (Val, Leu, Ile, Abu, Ival)
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: DAGPYGCCAK
Nearest Stachelhaus code(s):: Phe DAGALGACAK (68% 8� match); Trp DAGIVGACAK (56% 8� match)
Stachelhaus code match:: 70% (weak)

AMP-binding (1061..1444): X

nrpys: 6-clTrp

SVM prediction details:

Predicted physicochemical class:: N/A
Large clusters prediction:: N/A
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: DAAMLGGVGK
Nearest Stachelhaus code(s):: 6-clTrp DAAMCGGVAK (44% 8� match)
Stachelhaus code match:: 80% (moderate)

scaffold_106 - Region 1 - terpene

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Location: 80,082 - 111,763 nt. (total: 31,682 nt) Show pHMM detection rules used

Region on contig edge.

terpene: (Terpene_synth or Terpene_synth_C or phytoene_synt or Lycopene_cycl or terpene_cyclase or NapT7 or fung_ggpps or fung_ggpps2 or trichodiene_synth or TRI5)

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core biosynthetic genes

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scaffold_108 - Region 1 - NRPS-like

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Location: 55,641 - 111,493 nt. (total: 55,853 nt) Show pHMM detection rules used

Region on contig edge.

NRPS-like: cds((PP-binding or NAD_binding_4) and (AMP-binding or A-OX))

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core biosynthetic genes

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NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 1, location 55640 - 111493:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (X)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

68191

AMP-binding (55..357): X

nrpys: (unknown)

SVM prediction details:

NOTE: uncertain match

Predicted physicochemical class:: N/A
Large clusters prediction:: Aliphatic chain with H-bond donor (Asp, Asn, Glu, Gln, Aad)
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: ---YLGM--K
Nearest Stachelhaus code(s):
Stachelhaus code match:: 0% (weak)

scaffold_113 - Region 1 - fungal-RiPP-like

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Location: 12,149 - 103,455 nt. (total: 91,307 nt) Show pHMM detection rules used

fungal-RiPP-like: DUF3328

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core biosynthetic genes

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scaffold_114 - Region 1 - terpene

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Location: 60,888 - 92,515 nt. (total: 31,628 nt) Show pHMM detection rules used

terpene: (Terpene_synth or Terpene_synth_C or phytoene_synt or Lycopene_cycl or terpene_cyclase or NapT7 or fung_ggpps or fung_ggpps2 or trichodiene_synth or TRI5)

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scaffold_115 - Region 1 - NRPS,T1PKS

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Location: 40,042 - 110,636 nt. (total: 70,595 nt) Show pHMM detection rules used

Region on contig edge.

T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))
NRPS: cds(Condensation and (AMP-binding or A-OX))

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core biosynthetic genes

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NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 1, location 40041 - 110636:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (pk) + (pk - X)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

107005

PKS_AT (538..840): pk

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 75.0%; Methylmalonyl-CoA: 62.5%; Propionyl-CoA: 58.3%

minowa: Methylmalonyl-CoA

Prediction, score:

Methylmalonyl-CoA: 90.2
Methoxymalonyl-CoA: 70.4
Isobutyryl-CoA: 62.4
Ethylmalonyl-CoA: 57.8
Propionyl-CoA: 45.1
Malonyl-CoA: 45.1
Benzoyl-CoA: 31.1
2-Methylbutyryl-CoA: 28.0
trans-1,2-CPDA: 21.8
fatty_acid: 20.8
Acetyl-CoA: 16.8
CHC-CoA: 14.6
3-Methylbutyryl-CoA: 14.6
inactive: 0.0

2152165

PKS_AT (562..877): pk

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 79.2%; Methylmalonyl-CoA: 66.7%; Methoxymalonyl-CoA: 58.3%

minowa: Methylmalonyl-CoA

Prediction, score:

Methylmalonyl-CoA: 73.0
Methoxymalonyl-CoA: 64.7
Ethylmalonyl-CoA: 51.7
Malonyl-CoA: 35.8
Propionyl-CoA: 27.9
Isobutyryl-CoA: 27.4
Benzoyl-CoA: 24.9
3-Methylbutyryl-CoA: 22.0
2-Methylbutyryl-CoA: 21.6
trans-1,2-CPDA: 16.2
fatty_acid: 15.3
inactive: 13.5
CHC-CoA: 10.1
Acetyl-CoA: 9.1

AMP-binding (3070..3474): X

nrpys: Orn, Lys, Arg

SVM prediction details:

Predicted physicochemical class:: N/A
Large clusters prediction:: Long positively charged side chain (Orn, Lys, Arg)
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: DMAGLGCLCK
Nearest Stachelhaus code(s):: Hpg DAAHLGLLCK (50% 8� match)
Stachelhaus code match:: 70% (weak)

scaffold_129 - Region 1 - fungal-RiPP-like

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Location: 33,731 - 104,639 nt. (total: 70,909 nt) Show pHMM detection rules used

Region on contig edge.

fungal-RiPP-like: DUF3328

Legend:

core biosynthetic genes

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		NT	AA		NT	AA

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No matches found.

scaffold_133 - Region 1 - NRPS,T1PKS

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Location: 46,460 - 102,853 nt. (total: 56,394 nt) Show pHMM detection rules used

Region on contig edge.

NRPS: cds(Condensation and (AMP-binding or A-OX))
T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))

Legend:

core biosynthetic genes

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Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

Detailed domain annotation

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No matches found.

Module view

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NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 1, location 46459 - 102853:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (pk - X)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

2152684

PKS_AT (551..866): pk

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 79.2%; Methylmalonyl-CoA: 66.7%; Ethylmalonyl-CoA: 58.3%

minowa: Methylmalonyl-CoA

Prediction, score:

Methylmalonyl-CoA: 87.8
Methoxymalonyl-CoA: 73.7
Ethylmalonyl-CoA: 64.6
Isobutyryl-CoA: 51.4
Malonyl-CoA: 32.3
Benzoyl-CoA: 31.5
trans-1,2-CPDA: 30.7
Propionyl-CoA: 29.4
fatty_acid: 28.1
2-Methylbutyryl-CoA: 27.6
3-Methylbutyryl-CoA: 17.3
CHC-CoA: 16.5
inactive: 11.1
Acetyl-CoA: 3.3

AMP-binding (3028..3431): X

nrpys: Orn, Lys, Arg

SVM prediction details:

Predicted physicochemical class:: hydrophilic (Arg, Asp, Glu, Asn, Lys, Gln, Orn, Aad)
Large clusters prediction:: Long positively charged side chain (Orn, Lys, Arg)
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: DLAKFGCISK
Nearest Stachelhaus code(s):: MalAc NHDKFGSISK (59% 8� match); Hty DLAFTGCVTK (56% 8� match); 3Me-Glu DLGKTGVINK (53% 8� match); Asp DLTKVGHIGK (50% 8� match); Asn DLTKVGDVSK (47% 8� match)
Stachelhaus code match:: 60% (weak)

scaffold_147 - Region 1 - T1PKS

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Location: 15,254 - 84,052 nt. (total: 68,799 nt) Show pHMM detection rules used

T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))

Legend:

core biosynthetic genes

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Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

Detailed domain annotation

Selected features only

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No matches found.

Module view

Legend

NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 1, location 15253 - 84052:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (pk)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

2166867

PKS_AT (637..968): pk

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 75.0%; Methylmalonyl-CoA: 62.5%; Ethylmalonyl-CoA: 58.3%

minowa: Methylmalonyl-CoA

Prediction, score:

Methylmalonyl-CoA: 72.3
Methoxymalonyl-CoA: 65.6
Malonyl-CoA: 60.8
Propionyl-CoA: 38.1
Ethylmalonyl-CoA: 32.1
inactive: 18.9
CHC-CoA: 16.8
Benzoyl-CoA: 13.5
Isobutyryl-CoA: 9.3
2-Methylbutyryl-CoA: 3.8
trans-1,2-CPDA: 0.0
fatty_acid: 0.0
3-Methylbutyryl-CoA: 0.0
Acetyl-CoA: -0.8

scaffold_156 - Region 1 - fungal-RiPP-like

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Location: 1 - 79,336 nt. (total: 79,336 nt) Show pHMM detection rules used

Region on contig edge.

fungal-RiPP-like: DUF3328

Legend:

core biosynthetic genes

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No matches found.

scaffold_164 - Region 1 - NRPS-like

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Location: 6,722 - 70,123 nt. (total: 63,402 nt) Show pHMM detection rules used

NRPS-like: cds((PP-binding or NAD_binding_4) and (AMP-binding or A-OX))

Legend:

core biosynthetic genes

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No matches found.

NRPS/PKS monomers

NRPS/PKS monomer predictions

2153501

AMP-binding (36..426): X

nrpys: Ala, Gly, Val, Leu, Ile, Abu, Ival, Ser, Thr, Hpg, Dhpg, Cys, Pro, Hpr

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic (Ala, Gly, Val, Leu, Ile, Abu, Ival, Ser, Thr, Hpg, Dhpg, Cys, Pro, Hpr)
Large clusters prediction:: N/A
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: ---VMAFILK
Nearest Stachelhaus code(s):
Stachelhaus code match:: 0% (weak)

scaffold_169 - Region 1 - T1PKS

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Location: 46,937 - 85,682 nt. (total: 38,746 nt) Show pHMM detection rules used

Region on contig edge.

T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))

Legend:

core biosynthetic genes

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Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

Detailed domain annotation

Selected features only

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No matches found.

Module view

Legend

NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 1, location 46936 - 85682:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (pk)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

2112295

PKS_AT (541..849): pk

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 87.5%; Methylmalonyl-CoA: 66.7%; Ethylmalonyl-CoA: 62.5%

minowa: Methylmalonyl-CoA

Prediction, score:

Methylmalonyl-CoA: 96.0
Methoxymalonyl-CoA: 88.3
Ethylmalonyl-CoA: 64.7
Malonyl-CoA: 62.7
Isobutyryl-CoA: 60.9
2-Methylbutyryl-CoA: 45.4
Propionyl-CoA: 37.5
Benzoyl-CoA: 36.7
inactive: 31.6
trans-1,2-CPDA: 27.5
3-Methylbutyryl-CoA: 21.3
fatty_acid: 16.1
CHC-CoA: 10.3
Acetyl-CoA: 2.2

scaffold_172 - Region 1 - fungal-RiPP-like

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Location: 26,160 - 84,962 nt. (total: 58,803 nt) Show pHMM detection rules used

Region on contig edge.

fungal-RiPP-like: DUF3328

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scaffold_173 - Region 1 - terpene

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Location: 53,880 - 84,591 nt. (total: 30,712 nt) Show pHMM detection rules used

Region on contig edge.

terpene: (Terpene_synth or Terpene_synth_C or phytoene_synt or Lycopene_cycl or terpene_cyclase or NapT7 or fung_ggpps or fung_ggpps2 or trichodiene_synth or TRI5)

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scaffold_193 - Region 1 - T1PKS

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Location: 1 - 62,352 nt. (total: 62,352 nt) Show pHMM detection rules used

Region on contig edge.

T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))

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Predicted core structure(s)

For candidate cluster 1, location 0 - 62352:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (mal)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

480812

PKS_AT (904..1203): mal

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 79.2%; Methylmalonyl-CoA: 62.5%; inactive: 62.5%

minowa: Malonyl-CoA

Prediction, score:

Malonyl-CoA: 93.2
Methylmalonyl-CoA: 64.6
Methoxymalonyl-CoA: 59.0
inactive: 44.4
Propionyl-CoA: 37.0
Isobutyryl-CoA: 26.2
2-Methylbutyryl-CoA: 19.5
Ethylmalonyl-CoA: 18.3
CHC-CoA: 15.4
Benzoyl-CoA: 15.3
Acetyl-CoA: 11.7
3-Methylbutyryl-CoA: 11.7
fatty_acid: 11.6
trans-1,2-CPDA: 9.2

scaffold_200 - Region 1 - terpene

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Location: 211 - 31,437 nt. (total: 31,227 nt) Show pHMM detection rules used

Region on contig edge.

terpene: (Terpene_synth or Terpene_synth_C or phytoene_synt or Lycopene_cycl or terpene_cyclase or NapT7 or fung_ggpps or fung_ggpps2 or trichodiene_synth or TRI5)

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scaffold_206 - Region 1 - fungal-RiPP-like

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Location: 1 - 76,942 nt. (total: 76,942 nt) Show pHMM detection rules used

Region on contig edge.

fungal-RiPP-like: DUF3328

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scaffold_209 - Region 1 - fungal-RiPP-like

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Location: 164 - 76,607 nt. (total: 76,444 nt) Show pHMM detection rules used

Region on contig edge.

fungal-RiPP-like: DUF3328

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scaffold_21 - Region 1 - fungal-RiPP-like

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Location: 17,578 - 111,109 nt. (total: 93,532 nt) Show pHMM detection rules used

fungal-RiPP-like: DUF3328

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scaffold_211 - Region 1 - fungal-RiPP-like

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Location: 1 - 57,640 nt. (total: 57,640 nt) Show pHMM detection rules used

Region on contig edge.

fungal-RiPP-like: DUF3328

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scaffold_222 - Region 1 - T1PKS

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Location: 1 - 59,745 nt. (total: 59,745 nt) Show pHMM detection rules used

Region on contig edge.

T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))

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NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 1, location 0 - 59745:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (pk)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

2115062

PKS_AT (603..922): pk

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 75.0%; Methylmalonyl-CoA: 58.3%; Ethylmalonyl-CoA: 54.2%

minowa: Methylmalonyl-CoA

Prediction, score:

Methylmalonyl-CoA: 81.9
Methoxymalonyl-CoA: 77.6
Malonyl-CoA: 65.0
Ethylmalonyl-CoA: 50.5
Isobutyryl-CoA: 31.4
trans-1,2-CPDA: 24.6
fatty_acid: 24.2
Propionyl-CoA: 17.8
Benzoyl-CoA: 17.1
3-Methylbutyryl-CoA: 14.5
inactive: 13.0
CHC-CoA: 11.5
2-Methylbutyryl-CoA: 8.7
Acetyl-CoA: 6.6

scaffold_228 - Region 1 - NRPS

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Location: 14,601 - 71,618 nt. (total: 57,018 nt) Show pHMM detection rules used

Region on contig edge.

NRPS: cds(Condensation and (AMP-binding or A-OX))

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NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 1, location 14600 - 71618:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (Ala)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

586678

Search NORINE for peptide: strict or relaxed

AMP-binding (61..462): Ala

nrpys: Ala

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic (Ala, Gly, Val, Leu, Ile, Abu, Ival, Ser, Thr, Hpg, Dhpg, Cys, Pro, Hpr)
Large clusters prediction:: N/A
Small clusters prediction:: Tiny, hydrophilic, transition to aliphatic (Gly, Ala)
Single AA prediction:: ala (Ala)

Stachelhaus prediction details:

Stachelhaus sequence:: AMFACSGPIK
Nearest Stachelhaus code(s):
Stachelhaus code match:: 0% (weak)

scaffold_239 - Region 1 - fungal-RiPP-like

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Location: 1 - 69,471 nt. (total: 69,471 nt) Show pHMM detection rules used

Region on contig edge.

fungal-RiPP-like: DUF3328

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scaffold_246 - Region 1 - fungal-RiPP-like

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Location: 3,265 - 68,932 nt. (total: 65,668 nt) Show pHMM detection rules used

Region on contig edge.

fungal-RiPP-like: DUF3328

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scaffold_25 - Region 1 - T1PKS

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Location: 1 - 32,586 nt. (total: 32,586 nt) Show pHMM detection rules used

Region on contig edge.

T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))

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NRPS/PKS monomers

NRPS/PKS monomer predictions

2134200

PKS_AT (419..580): mmal

ATSignature: (unknown)

No matches above 50%

minowa: Methylmalonyl-CoA

Prediction, score:

Methylmalonyl-CoA: 19.5
Methoxymalonyl-CoA: 17.5
Malonyl-CoA: 11.0
Ethylmalonyl-CoA: 10.1
trans-1,2-CPDA: 0.0
inactive: 0.0
fatty_acid: 0.0
Propionyl-CoA: 0.0
Isobutyryl-CoA: 0.0
CHC-CoA: 0.0
Benzoyl-CoA: 0.0
Acetyl-CoA: 0.0
3-Methylbutyryl-CoA: 0.0
2-Methylbutyryl-CoA: 0.0

scaffold_252 - Region 1 - fungal-RiPP-like

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Location: 2,784 - 67,220 nt. (total: 64,437 nt) Show pHMM detection rules used

Region on contig edge.

fungal-RiPP-like: DUF3328

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scaffold_269 - Region 1 - fungal-RiPP-like

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Location: 1 - 46,358 nt. (total: 46,358 nt) Show pHMM detection rules used

Region on contig edge.

fungal-RiPP-like: DUF3328

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scaffold_295 - Region 1 - NRPS-like,T1PKS

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Location: 1 - 51,650 nt. (total: 51,650 nt) Show pHMM detection rules used

Region on contig edge.

T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))
NRPS-like: cds((PP-binding or NAD_binding_4) and (AMP-binding or A-OX))

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NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 1, location 0 - 51650:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (mal) + (X)

Direct lookup in NORINE database: strict or relaxed

For candidate cluster 2, location 0 - 44677:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (mal) + (X)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

2261175

AMP-binding (106..435): X

nrpys: Gly, Ala, Val, Leu, Ile, Abu, Ival

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic (Ala, Gly, Val, Leu, Ile, Abu, Ival, Ser, Thr, Hpg, Dhpg, Cys, Pro, Hpr)
Large clusters prediction:: Apolar, aliphatic (Gly, Ala, Val, Leu, Ile, Abu, Ival)
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: GFLMAGHALK
Nearest Stachelhaus code(s):: meOrs GFVMLGHLGK (62% 8� match); Val DALFAGGALK (35% 8� match)
Stachelhaus code match:: 60% (weak)

2118291

PKS_AT (907..1209): mal

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 62.5%; Propionyl-CoA: 54.2%; inactive: 54.2%

minowa: Malonyl-CoA

Prediction, score:

Malonyl-CoA: 72.8
Methoxymalonyl-CoA: 61.7
Methylmalonyl-CoA: 60.2
inactive: 48.4
Isobutyryl-CoA: 29.8
Benzoyl-CoA: 25.9
Ethylmalonyl-CoA: 22.0
Propionyl-CoA: 15.5
fatty_acid: 13.3
2-Methylbutyryl-CoA: 9.6
trans-1,2-CPDA: 9.5
CHC-CoA: 9.4
Acetyl-CoA: 4.3
3-Methylbutyryl-CoA: -1.8

scaffold_296 - Region 1 - T1PKS

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Location: 1 - 41,910 nt. (total: 41,910 nt) Show pHMM detection rules used

Region on contig edge.

T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))

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Predicted core structure(s)

For candidate cluster 1, location 0 - 41910:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (mal)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

2155998

PKS_AT (910..1200): mal

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 79.2%; inactive: 58.3%

minowa: Malonyl-CoA

Prediction, score:

Malonyl-CoA: 111.4
inactive: 78.0
Methoxymalonyl-CoA: 57.3
Methylmalonyl-CoA: 48.5
Propionyl-CoA: 29.5
fatty_acid: 13.6
Acetyl-CoA: 13.2
2-Methylbutyryl-CoA: 12.3
Ethylmalonyl-CoA: 9.8
trans-1,2-CPDA: 9.1
Isobutyryl-CoA: 8.1
CHC-CoA: 7.2
Benzoyl-CoA: 7.2
3-Methylbutyryl-CoA: 0.0

scaffold_321 - Region 1 - T1PKS

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Location: 25 - 54,382 nt. (total: 54,358 nt) Show pHMM detection rules used

Region on contig edge.

T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))

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Predicted core structure(s)

For candidate cluster 1, location 24 - 54382:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (mal)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

2334078

PKS_AT (551..845): mal

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 58.3%; inactive: 54.2%

minowa: Malonyl-CoA

Prediction, score:

Malonyl-CoA: 55.3
inactive: 50.4
Methoxymalonyl-CoA: 35.6
Methylmalonyl-CoA: 35.3
Propionyl-CoA: 16.3
CHC-CoA: 10.9
Benzoyl-CoA: 10.1
2-Methylbutyryl-CoA: 10.0
Ethylmalonyl-CoA: 9.9
fatty_acid: 9.5
trans-1,2-CPDA: 0.0
Isobutyryl-CoA: 0.0
Acetyl-CoA: 0.0
3-Methylbutyryl-CoA: 0.0

scaffold_33 - Region 1 - NRPS

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Location: 124,238 - 200,998 nt. (total: 76,761 nt) Show pHMM detection rules used

Region on contig edge.

NRPS: cds(Condensation and (AMP-binding or A-OX))

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Predicted core structure(s)

For candidate cluster 1, location 124237 - 200998:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (X - Ala) + (X)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

897721

AMP-binding (474..870): X

nrpys: Ala, Gly, Val, Leu, Ile, Abu, Ival, Ser, Thr, Hpg, Dhpg, Cys, Pro, Hpr

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic (Ala, Gly, Val, Leu, Ile, Abu, Ival, Ser, Thr, Hpg, Dhpg, Cys, Pro, Hpr)
Large clusters prediction:: N/A
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: DIQSAVGAIK
Nearest Stachelhaus code(s):
Stachelhaus code match:: 0% (weak)

2149161

AMP-binding (38..458): X

nrpys: Ala, Gly, Val, Leu, Ile, Abu, Ival, Ser, Thr, Hpg, Dhpg, Cys, Pro, Hpr

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic (Ala, Gly, Val, Leu, Ile, Abu, Ival, Ser, Thr, Hpg, Dhpg, Cys, Pro, Hpr)
Large clusters prediction:: N/A
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: GLGYVGGVIK
Nearest Stachelhaus code(s):: nohBza GLGLVGAIIK (35% 8� match); Abu DLGYVAGVFK (29% 8� match)
Stachelhaus code match:: 70% (weak)

898331

Search NORINE for peptide: strict or relaxed

AMP-binding (882..1276): X

nrpys: Ala, Gly, Val, Leu, Ile, Abu, Ival, Ser, Thr, Hpg, Dhpg, Cys, Pro, Hpr

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic (Ala, Gly, Val, Leu, Ile, Abu, Ival, Ser, Thr, Hpg, Dhpg, Cys, Pro, Hpr)
Large clusters prediction:: N/A
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: DISNVAAILK
Nearest Stachelhaus code(s):: bOH-Tyr DTSKVAAICK (56% 8� match)
Stachelhaus code match:: 70% (weak)

AMP-binding (1970..2372): Ala

nrpys: Ala

SVM prediction details:

Predicted physicochemical class:: N/A
Large clusters prediction:: N/A
Small clusters prediction:: N/A
Single AA prediction:: ala (Ala)

Stachelhaus prediction details:

Stachelhaus sequence:: DVQGVNSINK
Nearest Stachelhaus code(s):: Gln DVQIVGGIHK (76% 8� match); bOH-Gln DAQNIASINK (68% 8� match); Arg DVENVGAINK (41% 8� match)
Stachelhaus code match:: 60% (weak)

scaffold_335 - Region 1 - terpene

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Location: 1 - 22,983 nt. (total: 22,983 nt) Show pHMM detection rules used

Region on contig edge.

terpene: (Terpene_synth or Terpene_synth_C or phytoene_synt or Lycopene_cycl or terpene_cyclase or NapT7 or fung_ggpps or fung_ggpps2 or trichodiene_synth or TRI5)

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scaffold_338 - Region 1 - T1PKS

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Location: 5,706 - 53,141 nt. (total: 47,436 nt) Show pHMM detection rules used

Region on contig edge.

T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))

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NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 1, location 5705 - 53141:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (mal)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

2156627

PKS_AT (914..1206): mal

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 58.3%; inactive: 54.2%

minowa: Malonyl-CoA

Prediction, score:

Malonyl-CoA: 54.2
Methoxymalonyl-CoA: 50.2
inactive: 46.2
Methylmalonyl-CoA: 42.2
fatty_acid: 30.9
Ethylmalonyl-CoA: 22.6
CHC-CoA: 19.6
Propionyl-CoA: 18.5
trans-1,2-CPDA: 17.3
2-Methylbutyryl-CoA: 17.2
Benzoyl-CoA: 14.8
Isobutyryl-CoA: 14.6
3-Methylbutyryl-CoA: 13.2
Acetyl-CoA: 11.1

scaffold_339 - Region 1 - NRPS-like

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Location: 1 - 51,229 nt. (total: 51,229 nt) Show pHMM detection rules used

Region on contig edge.

NRPS-like: cds((PP-binding or NAD_binding_4) and (AMP-binding or A-OX))

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Predicted core structure(s)

For candidate cluster 1, location 0 - 51229:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (X)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

2156637

AMP-binding (24..403): X

nrpys: Phe, Trp, Ph-Gly, Tyr, bOH-Tyr

SVM prediction details:

Predicted physicochemical class:: N/A
Large clusters prediction:: Aromatic side chain (Phe, Trp, Ph-Gly, Tyr, bOH-Tyr)
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: ---LIGLVLK
Nearest Stachelhaus code(s):
Stachelhaus code match:: 0% (weak)

scaffold_345 - Region 1 - NRPS-like

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Location: 1 - 48,869 nt. (total: 48,869 nt) Show pHMM detection rules used

Region on contig edge.

NRPS-like: cds((PP-binding or NAD_binding_4) and (AMP-binding or A-OX))

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Predicted core structure(s)

For candidate cluster 1, location 0 - 48869:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (X)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

929882

AMP-binding (28..430): X

nrpys: (unknown)

SVM prediction details:

Predicted physicochemical class:: hydrophilic (Arg, Asp, Glu, Asn, Lys, Gln, Orn, Aad)
Large clusters prediction:: N/A
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: VATFPGAAGK
Nearest Stachelhaus code(s):: Ppa VATFIGGAGK (74% 8� match)
Stachelhaus code match:: 80% (moderate)

scaffold_352 - Region 1 - T1PKS

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Location: 1 - 49,090 nt. (total: 49,090 nt) Show pHMM detection rules used

Region on contig edge.

T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))

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Predicted core structure(s)

For candidate cluster 1, location 0 - 49090:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (mal)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

2156812

PKS_AT (915..1205): mal

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 79.2%; inactive: 54.2%

minowa: Malonyl-CoA

Prediction, score:

Malonyl-CoA: 104.9
Methoxymalonyl-CoA: 62.4
Methylmalonyl-CoA: 56.0
inactive: 51.1
Propionyl-CoA: 30.3
Ethylmalonyl-CoA: 26.4
2-Methylbutyryl-CoA: 22.3
fatty_acid: 22.0
CHC-CoA: 18.0
3-Methylbutyryl-CoA: 18.0
Isobutyryl-CoA: 16.9
Benzoyl-CoA: 15.3
Acetyl-CoA: 14.3
trans-1,2-CPDA: 9.8

scaffold_357 - Region 1 - fungal-RiPP-like

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Location: 1 - 50,762 nt. (total: 50,762 nt) Show pHMM detection rules used

Region on contig edge.

fungal-RiPP-like: DUF3328

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scaffold_364 - Region 1 - NRPS-like

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Location: 11,091 - 49,889 nt. (total: 38,799 nt) Show pHMM detection rules used

Region on contig edge.

NRPS-like: cds((PP-binding or NAD_binding_4) and (AMP-binding or A-OX))

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Predicted core structure(s)

For candidate cluster 1, location 11090 - 49889:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (X)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

2336713

AMP-binding (45..369): X

nrpys: Ala, Gly, Val, Leu, Ile, Abu, Ival, Ser, Thr, Hpg, Dhpg, Cys, Pro, Hpr

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic (Ala, Gly, Val, Leu, Ile, Abu, Ival, Ser, Thr, Hpg, Dhpg, Cys, Pro, Hpr)
Large clusters prediction:: N/A
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: -VFYISYQIK
Nearest Stachelhaus code(s):: Pro DVQYISGVIK (38% 8� match)
Stachelhaus code match:: 60% (weak)

scaffold_365 - Region 1 - terpene

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Location: 1 - 21,801 nt. (total: 21,801 nt) Show pHMM detection rules used

Region on contig edge.

terpene: (Terpene_synth or Terpene_synth_C or phytoene_synt or Lycopene_cycl or terpene_cyclase or NapT7 or fung_ggpps or fung_ggpps2 or trichodiene_synth or TRI5)

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scaffold_37 - Region 1 - fungal-RiPP-like

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Location: 105,648 - 194,000 nt. (total: 88,353 nt) Show pHMM detection rules used

Region on contig edge.

fungal-RiPP-like: DUF3328

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scaffold_372 - Region 1 - terpene

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Location: 4,400 - 35,626 nt. (total: 31,227 nt) Show pHMM detection rules used

Region on contig edge.

terpene: (Terpene_synth or Terpene_synth_C or phytoene_synt or Lycopene_cycl or terpene_cyclase or NapT7 or fung_ggpps or fung_ggpps2 or trichodiene_synth or TRI5)

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scaffold_379 - Region 1 - T1PKS

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Location: 1 - 47,899 nt. (total: 47,899 nt) Show pHMM detection rules used

Region on contig edge.

T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))

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Predicted core structure(s)

For candidate cluster 1, location 0 - 47899:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (mal)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

2121442

PKS_AT (909..1204): mal

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 79.2%; Methylmalonyl-CoA: 54.2%; Isobutyryl-CoA: 54.2%

minowa: Malonyl-CoA

Prediction, score:

Malonyl-CoA: 96.4
Methylmalonyl-CoA: 65.4
Methoxymalonyl-CoA: 56.8
inactive: 54.3
Propionyl-CoA: 50.5
2-Methylbutyryl-CoA: 34.5
CHC-CoA: 21.1
Ethylmalonyl-CoA: 18.3
Benzoyl-CoA: 17.8
Isobutyryl-CoA: 17.2
fatty_acid: 15.4
Acetyl-CoA: 14.6
trans-1,2-CPDA: 11.6
3-Methylbutyryl-CoA: 10.3

scaffold_391 - Region 1 - T1PKS,terpene

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Location: 1 - 46,927 nt. (total: 46,927 nt) Show pHMM detection rules used

Region on contig edge.

T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))
terpene: (Terpene_synth or Terpene_synth_C or phytoene_synt or Lycopene_cycl or terpene_cyclase or NapT7 or fung_ggpps or fung_ggpps2 or trichodiene_synth or TRI5)

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Predicted core structure(s)

For candidate cluster 1, location 0 - 46927:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (pk)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

2338613

PKS_AT (541..860): pk

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 70.8%; Methylmalonyl-CoA: 58.3%; Propionyl-CoA: 54.2%

minowa: Methylmalonyl-CoA

Prediction, score:

Methylmalonyl-CoA: 72.8
Methoxymalonyl-CoA: 68.3
Malonyl-CoA: 59.7
Isobutyryl-CoA: 51.6
Ethylmalonyl-CoA: 42.9
Propionyl-CoA: 28.6
3-Methylbutyryl-CoA: 24.4
Benzoyl-CoA: 24.3
inactive: 19.7
fatty_acid: 12.0
2-Methylbutyryl-CoA: 7.1
trans-1,2-CPDA: 4.9
CHC-CoA: 0.0
Acetyl-CoA: 0.0

scaffold_40 - Region 1 - terpene

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Location: 168,461 - 189,691 nt. (total: 21,231 nt) Show pHMM detection rules used

Region on contig edge.

terpene: (Terpene_synth or Terpene_synth_C or phytoene_synt or Lycopene_cycl or terpene_cyclase or NapT7 or fung_ggpps or fung_ggpps2 or trichodiene_synth or TRI5)

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scaffold_404 - Region 1 - indole

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Location: 1 - 25,282 nt. (total: 25,282 nt) Show pHMM detection rules used

Region on contig edge.

indole: (indsynth or dmat or indole_PTase)

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scaffold_426 - Region 1 - indole

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Location: 21,489 - 41,976 nt. (total: 20,488 nt) Show pHMM detection rules used

Region on contig edge.

indole: (indsynth or dmat or indole_PTase)

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scaffold_429 - Region 1 - NRPS

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Location: 1 - 41,729 nt. (total: 41,729 nt) Show pHMM detection rules used

Region on contig edge.

NRPS: cds(Condensation and (AMP-binding or A-OX))

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Predicted core structure(s)

For candidate cluster 1, location 0 - 41729:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (D-X - X - X - D-X)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

1169059

AMP-binding (245..641): X

nrpys: nDodec

SVM prediction details:

Predicted physicochemical class:: N/A
Large clusters prediction:: N/A
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: DVLFVGGVAK
Nearest Stachelhaus code(s):: nDodec DVLFIGGVAK (79% 8� match)
Stachelhaus code match:: 90% (moderate)

AMP-binding (1784..2187): X

nrpys: Ala, Gly, Val, Leu, Ile, Abu, Ival, Ser, Thr, Hpg, Dhpg, Cys, Pro, Hpr

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic (Ala, Gly, Val, Leu, Ile, Abu, Ival, Ser, Thr, Hpg, Dhpg, Cys, Pro, Hpr)
Large clusters prediction:: N/A
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: DVQDSGVVTK
Nearest Stachelhaus code(s):: dn-dohHep DVFDFGGVTK (59% 8� match); Gln or Glu DAQDLGVVDK (56% 8� match); Ile DAQDLGVVDK (53% 8� match); Ahp DVENAGVVTK (44% 8� match)
Stachelhaus code match:: 70% (weak)

AMP-binding (2903..3298): X

nrpys: (unknown)

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic (Ala, Gly, Val, Leu, Ile, Abu, Ival, Ser, Thr, Hpg, Dhpg, Cys, Pro, Hpr)
Large clusters prediction:: Apolar, aliphatic (Gly, Ala, Val, Leu, Ile, Abu, Ival)
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: DVSFAGSIWK
Nearest Stachelhaus code(s):: Asn DVAFTGSIWK (76% 8� match)
Stachelhaus code match:: 80% (moderate)

AMP-binding (3979..4371): X

nrpys: (unknown)

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic (Ala, Gly, Val, Leu, Ile, Abu, Ival, Ser, Thr, Hpg, Dhpg, Cys, Pro, Hpr)
Large clusters prediction:: Apolar, aliphatic (Gly, Ala, Val, Leu, Ile, Abu, Ival)
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: DVGYSGIIWK
Nearest Stachelhaus code(s):: Ser DVAYSGMIWK (74% 8� match)
Stachelhaus code match:: 80% (moderate)

scaffold_439 - Region 1 - T1PKS

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Location: 1 - 40,622 nt. (total: 40,622 nt) Show pHMM detection rules used

Region on contig edge.

T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))

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Predicted core structure(s)

For candidate cluster 1, location 0 - 40622:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (mal)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

1188911

PKS_AT (905..1203): mal

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 83.3%; inactive: 58.3%; Methylmalonyl-CoA: 54.2%

minowa: Malonyl-CoA

Prediction, score:

Malonyl-CoA: 122.0
Methylmalonyl-CoA: 70.7
Methoxymalonyl-CoA: 70.7
inactive: 69.9
Propionyl-CoA: 44.2
Ethylmalonyl-CoA: 36.6
Acetyl-CoA: 33.0
2-Methylbutyryl-CoA: 26.3
CHC-CoA: 23.9
Benzoyl-CoA: 20.2
Isobutyryl-CoA: 19.4
3-Methylbutyryl-CoA: 17.4
fatty_acid: 16.5
trans-1,2-CPDA: 12.3

scaffold_440 - Region 1 - NRPS-like

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Location: 3,504 - 40,619 nt. (total: 37,116 nt) Show pHMM detection rules used

Region on contig edge.

NRPS-like: cds((PP-binding or NAD_binding_4) and (AMP-binding or A-OX))

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Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

Detailed domain annotation

Selected features only

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NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 1, location 3503 - 40619:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (X)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

2459043

AMP-binding (33..440): X

nrpys: (unknown)

SVM prediction details:

Predicted physicochemical class:: hydrophilic (Arg, Asp, Glu, Asn, Lys, Gln, Orn, Aad)
Large clusters prediction:: N/A
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: VASFIGGAGK
Nearest Stachelhaus code(s):: Ppa VATFIGGAGK (91% 8� match)
Stachelhaus code match:: 90% (moderate)

scaffold_488 - Region 1 - T1PKS

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Location: 671 - 35,980 nt. (total: 35,310 nt) Show pHMM detection rules used

Region on contig edge.

T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))

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Predicted core structure(s)

For candidate cluster 1, location 670 - 35980:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (pk)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

1286353

PKS_AT (532..824): pk

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 75.0%; Methylmalonyl-CoA: 70.8%; CE-Malonyl-CoA: 62.5%

minowa: Methylmalonyl-CoA

Prediction, score:

Methylmalonyl-CoA: 106.5
Methoxymalonyl-CoA: 90.1
Ethylmalonyl-CoA: 80.2
Malonyl-CoA: 59.4
Isobutyryl-CoA: 58.4
Propionyl-CoA: 46.1
Acetyl-CoA: 43.4
2-Methylbutyryl-CoA: 43.4
trans-1,2-CPDA: 35.7
Benzoyl-CoA: 33.5
3-Methylbutyryl-CoA: 29.7
fatty_acid: 24.8
CHC-CoA: 14.1
inactive: 0.0

scaffold_49 - Region 1 - T1PKS

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Location: 43,309 - 111,859 nt. (total: 68,551 nt) Show pHMM detection rules used

T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))

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NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 1, location 43308 - 111859:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (pk)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

2102915

PKS_AT (618..943): pk

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 79.2%; Methylmalonyl-CoA: 75.0%; Ethylmalonyl-CoA: 66.7%

minowa: Methylmalonyl-CoA

Prediction, score:

Methylmalonyl-CoA: 64.5
Methoxymalonyl-CoA: 62.2
Malonyl-CoA: 55.5
Ethylmalonyl-CoA: 36.9
Isobutyryl-CoA: 33.8
Propionyl-CoA: 32.2
inactive: 26.0
fatty_acid: 20.7
Benzoyl-CoA: 18.7
Acetyl-CoA: 15.0
CHC-CoA: 11.2
2-Methylbutyryl-CoA: 8.8
trans-1,2-CPDA: 8.0
3-Methylbutyryl-CoA: -2.9

scaffold_491 - Region 1 - T1PKS

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Location: 1 - 35,846 nt. (total: 35,846 nt) Show pHMM detection rules used

Region on contig edge.

T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))

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NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 1, location 0 - 35846:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (pk)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

2343665

PKS_AT (579..901): pk

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 75.0%; Methylmalonyl-CoA: 62.5%; Propionyl-CoA: 58.3%

minowa: Methoxymalonyl-CoA

Prediction, score:

Methoxymalonyl-CoA: 83.5
Methylmalonyl-CoA: 80.3
Malonyl-CoA: 77.4
Isobutyryl-CoA: 49.1
Ethylmalonyl-CoA: 40.9
Propionyl-CoA: 31.6
3-Methylbutyryl-CoA: 30.8
Benzoyl-CoA: 26.2
inactive: 25.6
trans-1,2-CPDA: 23.4
fatty_acid: 17.9
CHC-CoA: 13.0
Acetyl-CoA: 12.2
2-Methylbutyryl-CoA: 5.7

scaffold_5 - Region 1 - T1PKS

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Location: 389,143 - 439,479 nt. (total: 50,337 nt) Show pHMM detection rules used

Region on contig edge.

T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))

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Predicted core structure(s)

For candidate cluster 1, location 389142 - 439479:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (pk)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

2096696

PKS_AT (580..873): pk

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 83.3%; Methylmalonyl-CoA: 70.8%; Ethylmalonyl-CoA: 66.7%

minowa: Methylmalonyl-CoA

Prediction, score:

Methylmalonyl-CoA: 111.5
Ethylmalonyl-CoA: 88.1
Methoxymalonyl-CoA: 86.9
Malonyl-CoA: 64.1
Isobutyryl-CoA: 63.3
trans-1,2-CPDA: 38.6
2-Methylbutyryl-CoA: 36.8
Propionyl-CoA: 36.5
Acetyl-CoA: 32.9
fatty_acid: 26.2
CHC-CoA: 24.0
Benzoyl-CoA: 23.7
3-Methylbutyryl-CoA: 13.0
inactive: 0.0

scaffold_504 - Region 1 - T1PKS

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Location: 1 - 34,482 nt. (total: 34,482 nt) Show pHMM detection rules used

Region on contig edge.

T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))

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Predicted core structure(s)

For candidate cluster 1, location 0 - 34482:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (pk)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

2144048

PKS_AT (552..886): pk

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 79.2%; Methylmalonyl-CoA: 66.7%; Ethylmalonyl-CoA: 58.3%

minowa: Methylmalonyl-CoA

Prediction, score:

Methylmalonyl-CoA: 60.3
Methoxymalonyl-CoA: 60.2
Isobutyryl-CoA: 29.5
Malonyl-CoA: 27.0
Ethylmalonyl-CoA: 24.0
Propionyl-CoA: 23.4
fatty_acid: 19.7
2-Methylbutyryl-CoA: 14.5
Benzoyl-CoA: 14.4
inactive: 13.1
CHC-CoA: 10.1
trans-1,2-CPDA: 7.5
Acetyl-CoA: 0.0
3-Methylbutyryl-CoA: 0.0

scaffold_509 - Region 1 - NRPS-like

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Location: 1 - 33,484 nt. (total: 33,484 nt) Show pHMM detection rules used

Region on contig edge.

NRPS-like: cds((PP-binding or NAD_binding_4) and (AMP-binding or A-OX))

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Predicted core structure(s)

For candidate cluster 1, location 0 - 33484:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (X)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

1339515

AMP-binding (45..378): X

nrpys: Ala, Gly, Val, Leu, Ile, Abu, Ival, Ser, Thr, Hpg, Dhpg, Cys, Pro, Hpr

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic (Ala, Gly, Val, Leu, Ile, Abu, Ival, Ser, Thr, Hpg, Dhpg, Cys, Pro, Hpr)
Large clusters prediction:: N/A
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: HGACGGRFLK
Nearest Stachelhaus code(s):
Stachelhaus code match:: 0% (weak)

scaffold_51 - Region 1 - NRPS-like

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Location: 32,522 - 84,886 nt. (total: 52,365 nt) Show pHMM detection rules used

NRPS-like: cds((PP-binding or NAD_binding_4) and (AMP-binding or A-OX))

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Predicted core structure(s)

For candidate cluster 1, location 32521 - 84886:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (X)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

2103050

AMP-binding (22..342): X

nrpys: (unknown)

SVM prediction details:

Predicted physicochemical class:: N/A
Large clusters prediction:: N/A
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: -ANAMAH--K
Nearest Stachelhaus code(s):
Stachelhaus code match:: 0% (weak)

scaffold_51 - Region 2 - NRPS,T1PKS

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Location: 114,075 - 163,148 nt. (total: 49,074 nt) Show pHMM detection rules used

Region on contig edge.

NRPS: cds(Condensation and (AMP-binding or A-OX))
T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))

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Predicted core structure(s)

For candidate cluster 2, location 114074 - 163148:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (pk - X)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

2103086

PKS_AT (555..870): pk

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 75.0%; Methoxymalonyl-CoA: 62.5%; Methylmalonyl-CoA: 62.5%

minowa: Methylmalonyl-CoA

Prediction, score:

Methylmalonyl-CoA: 95.7
Methoxymalonyl-CoA: 75.9
Ethylmalonyl-CoA: 62.3
trans-1,2-CPDA: 44.0
Isobutyryl-CoA: 42.2
Malonyl-CoA: 39.0
Propionyl-CoA: 37.3
Benzoyl-CoA: 35.6
2-Methylbutyryl-CoA: 21.3
fatty_acid: 19.8
CHC-CoA: 18.7
Acetyl-CoA: 12.0
3-Methylbutyryl-CoA: 10.1
inactive: 0.0

AMP-binding (3024..3423): X

nrpys: Ala, Gly, Val, Leu, Ile, Abu, Ival, Ser, Thr, Hpg, Dhpg, Cys, Pro, Hpr

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic (Ala, Gly, Val, Leu, Ile, Abu, Ival, Ser, Thr, Hpg, Dhpg, Cys, Pro, Hpr)
Large clusters prediction:: N/A
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: DVTYLAVCGK
Nearest Stachelhaus code(s):: Ala DVFSLAVVYK (53% 8� match)
Stachelhaus code match:: 60% (weak)

scaffold_517 - Region 1 - NRPS

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Location: 1 - 32,852 nt. (total: 32,852 nt) Show pHMM detection rules used

Region on contig edge.

NRPS: cds(Condensation and (AMP-binding or A-OX))

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Predicted core structure(s)

For candidate cluster 1, location 0 - 32852:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (X - X)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

1352690

AMP-binding (57..442): X

nrpys: Asp, Asn, Glu, Gln, Aad

SVM prediction details:

Predicted physicochemical class:: hydrophilic (Arg, Asp, Glu, Asn, Lys, Gln, Orn, Aad)
Large clusters prediction:: Aliphatic chain with H-bond donor (Asp, Asn, Glu, Gln, Aad)
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: SARESGAQLK
Nearest Stachelhaus code(s):
Stachelhaus code match:: 0% (weak)

AMP-binding (1092..1481): X

nrpys: Gly, Ala, Val, Leu, Ile, Abu, Ival

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic (Ala, Gly, Val, Leu, Ile, Abu, Ival, Ser, Thr, Hpg, Dhpg, Cys, Pro, Hpr)
Large clusters prediction:: Apolar, aliphatic (Gly, Ala, Val, Leu, Ile, Abu, Ival)
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: DAYMNCGILK
Nearest Stachelhaus code(s):: Val DAWMFAAILK (53% 8� match)
Stachelhaus code match:: 60% (weak)

scaffold_523 - Region 1 - T1PKS

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Location: 1 - 31,852 nt. (total: 31,852 nt) Show pHMM detection rules used

Region on contig edge.

T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))

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Predicted core structure(s)

For candidate cluster 1, location 0 - 31852:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (mal)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

2345276

PKS_AT (907..1205): mal

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 91.7%; inactive: 58.3%; Methylmalonyl-CoA: 54.2%

minowa: Malonyl-CoA

Prediction, score:

Malonyl-CoA: 82.4
inactive: 45.9
Methoxymalonyl-CoA: 34.1
Methylmalonyl-CoA: 28.3
fatty_acid: 20.7
Propionyl-CoA: 11.6
2-Methylbutyryl-CoA: 10.5
Isobutyryl-CoA: 9.4
Benzoyl-CoA: 9.2
trans-1,2-CPDA: 0.0
Ethylmalonyl-CoA: 0.0
CHC-CoA: 0.0
Acetyl-CoA: 0.0
3-Methylbutyryl-CoA: 0.0

scaffold_528 - Region 1 - T1PKS

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Location: 1 - 31,665 nt. (total: 31,665 nt) Show pHMM detection rules used

Region on contig edge.

T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))

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Predicted core structure(s)

For candidate cluster 1, location 0 - 31665:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (mal)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

2125734

PKS_AT (904..1200): mal

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 75.0%; Methylmalonyl-CoA: 54.2%

minowa: Malonyl-CoA

Prediction, score:

Malonyl-CoA: 103.8
Methylmalonyl-CoA: 61.1
Methoxymalonyl-CoA: 57.4
inactive: 46.3
Propionyl-CoA: 34.8
Isobutyryl-CoA: 32.2
2-Methylbutyryl-CoA: 29.7
Ethylmalonyl-CoA: 17.9
Benzoyl-CoA: 16.0
CHC-CoA: 14.3
3-Methylbutyryl-CoA: 12.1
fatty_acid: 10.7
trans-1,2-CPDA: 9.3
Acetyl-CoA: 8.1

scaffold_554 - Region 1 - terpene

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Location: 1 - 22,294 nt. (total: 22,294 nt) Show pHMM detection rules used

Region on contig edge.

terpene: (Terpene_synth or Terpene_synth_C or phytoene_synt or Lycopene_cycl or terpene_cyclase or NapT7 or fung_ggpps or fung_ggpps2 or trichodiene_synth or TRI5)

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scaffold_56 - Region 1 - T1PKS

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Location: 1 - 61,470 nt. (total: 61,470 nt) Show pHMM detection rules used

Region on contig edge.

T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))

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Predicted core structure(s)

For candidate cluster 1, location 0 - 61470:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (mal)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

2207366

PKS_AT (919..1213): mal

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 62.5%; Ethylmalonyl-CoA: 54.2%; inactive: 54.2%

minowa: Malonyl-CoA

Prediction, score:

Malonyl-CoA: 65.9
Methoxymalonyl-CoA: 60.6
Methylmalonyl-CoA: 54.8
inactive: 48.4
Ethylmalonyl-CoA: 30.8
Propionyl-CoA: 23.0
CHC-CoA: 22.1
fatty_acid: 21.3
2-Methylbutyryl-CoA: 16.7
trans-1,2-CPDA: 14.4
3-Methylbutyryl-CoA: 13.5
Isobutyryl-CoA: 13.0
Acetyl-CoA: 12.5
Benzoyl-CoA: 9.0

2103579

AMP-binding (125..292): X

nrpys: (unknown)

SVM prediction details:

NOTE: uncertain match

Predicted physicochemical class:: hydrophobic-aromatic (Phe, Tyr, diOH-Bz, Ph-Gly, bOH-Tyr)
Large clusters prediction:: N/A
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: ---AFAV--K
Nearest Stachelhaus code(s):
Stachelhaus code match:: 0% (weak)

scaffold_56 - Region 2 - NRPS-like

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Location: 87,692 - 151,689 nt. (total: 63,998 nt) Show pHMM detection rules used

NRPS-like: cds((PP-binding or NAD_binding_4) and (AMP-binding or A-OX))

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NRPS/PKS monomers

NRPS/PKS monomer predictions

1423399

AMP-binding (263..657): X

nrpys: Arg, Asp, Glu, Asn, Lys, Gln, Orn, Aad

SVM prediction details:

Predicted physicochemical class:: hydrophilic (Arg, Asp, Glu, Asn, Lys, Gln, Orn, Aad)
Large clusters prediction:: N/A
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: DVMHSGCACK
Nearest Stachelhaus code(s):: Glu DVTHSGSVTK (62% 8� match); Leu DAMLVGAACK (50% 8� match); Hpg DVYHLGLLCK (44% 8� match)
Stachelhaus code match:: 60% (weak)

scaffold_560 - Region 1 - T1PKS

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Location: 1 - 29,164 nt. (total: 29,164 nt) Show pHMM detection rules used

Region on contig edge.

T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))

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NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 1, location 0 - 29164:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (pk)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

2290990

PKS_AT (603..929): pk

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 75.0%; Methylmalonyl-CoA: 66.7%; Ethylmalonyl-CoA: 58.3%

minowa: Methoxymalonyl-CoA

Prediction, score:

Methoxymalonyl-CoA: 80.3
Methylmalonyl-CoA: 75.5
Malonyl-CoA: 66.5
Isobutyryl-CoA: 42.2
Ethylmalonyl-CoA: 37.0
trans-1,2-CPDA: 29.8
inactive: 27.7
CHC-CoA: 27.1
fatty_acid: 25.6
2-Methylbutyryl-CoA: 21.6
3-Methylbutyryl-CoA: 18.6
Propionyl-CoA: 17.9
Benzoyl-CoA: 14.3
Acetyl-CoA: 6.6

scaffold_575 - Region 1 - T1PKS

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Location: 1 - 28,454 nt. (total: 28,454 nt) Show pHMM detection rules used

Region on contig edge.

T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))

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NRPS/PKS monomers

NRPS/PKS monomer predictions

2347827

AMP-binding (46..347): X

nrpys: (unknown)

SVM prediction details:

Predicted physicochemical class:: N/A
Large clusters prediction:: N/A
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: --AVAGF--K
Nearest Stachelhaus code(s):
Stachelhaus code match:: 0% (weak)

2159145

PKS_AT (498..738): pk

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 66.7%; Methylmalonyl-CoA: 54.2%

minowa: Methoxymalonyl-CoA

Prediction, score:

Methoxymalonyl-CoA: 32.7
Methylmalonyl-CoA: 23.4
Malonyl-CoA: 18.3
fatty_acid: 14.8
Isobutyryl-CoA: 12.2
2-Methylbutyryl-CoA: 10.5
Benzoyl-CoA: 9.6
Ethylmalonyl-CoA: 9.3
trans-1,2-CPDA: 0.0
inactive: 0.0
Propionyl-CoA: 0.0
CHC-CoA: 0.0
Acetyl-CoA: 0.0
3-Methylbutyryl-CoA: 0.0

scaffold_587 - Region 1 - terpene

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Location: 5,201 - 27,656 nt. (total: 22,456 nt) Show pHMM detection rules used

Region on contig edge.

terpene: (Terpene_synth or Terpene_synth_C or phytoene_synt or Lycopene_cycl or terpene_cyclase or NapT7 or fung_ggpps or fung_ggpps2 or trichodiene_synth or TRI5)

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scaffold_593 - Region 1 - NRPS-like

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Location: 1 - 27,124 nt. (total: 27,124 nt) Show pHMM detection rules used

Region on contig edge.

NRPS-like: cds((PP-binding or NAD_binding_4) and (AMP-binding or A-OX))

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NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 1, location 0 - 27124:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (Aad)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

2293488

Search NORINE for peptide: strict or relaxed

AMP-binding (268..738): Aad

nrpys: Aad

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic (Ala, Gly, Val, Leu, Ile, Abu, Ival, Ser, Thr, Hpg, Dhpg, Cys, Pro, Hpr)
Large clusters prediction:: Aliphatic chain with H-bond donor (Asp, Asn, Glu, Gln, Aad)
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: DPRHFVMRAK
Nearest Stachelhaus code(s):: Aad DPRHFVMRAK (100% 8� match)
Stachelhaus code match:: 100% (strong)

scaffold_596 - Region 1 - terpene

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Location: 1 - 26,792 nt. (total: 26,792 nt) Show pHMM detection rules used

Region on contig edge.

terpene: (Terpene_synth or Terpene_synth_C or phytoene_synt or Lycopene_cycl or terpene_cyclase or NapT7 or fung_ggpps or fung_ggpps2 or trichodiene_synth or TRI5)

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scaffold_598 - Region 1 - NRP-metallophore,NRPS

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Location: 1 - 26,662 nt. (total: 26,662 nt) Show pHMM detection rules used

Region on contig edge.

NRPS: cds(Condensation and (AMP-binding or A-OX))
NRP-metallophore: (VibH_like or Cy_tandem or (cds(Condensation and AMP-binding) and ((IBH_Asp and not SBH_Asp) or IBH_His or TBH_Asp or CyanoBH_Asp1 or CyanoBH_Asp2 or IPL or SalSyn or (EntA and EntC) or (GrbD and GrbE) or (FbnL and FbnM) or PvdO or PvdP or (Orn_monoox and not (KtzT or MetRS-like)) or Lys_monoox or VbsL)))

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No matches found.

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NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 1, location 0 - 26662:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (X - X - X)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

2159314

AMP-binding (189..583): X

nrpys: Phe, Tyr, diOH-Bz, Ph-Gly, bOH-Tyr

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aromatic (Phe, Tyr, diOH-Bz, Ph-Gly, bOH-Tyr)
Large clusters prediction:: N/A
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: DVFELIMIHK
Nearest Stachelhaus code(s):: Orn DVSELGTINK (59% 8� match); Dab DVGELSSIDK (44% 8� match); Ser DLFNLGLIHK (38% 8� match)
Stachelhaus code match:: 60% (weak)

AMP-binding (1243..1665): X

nrpys: Gly, Ala, Val, Leu, Ile, Abu, Ival

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic (Ala, Gly, Val, Leu, Ile, Abu, Ival, Ser, Thr, Hpg, Dhpg, Cys, Pro, Hpr)
Large clusters prediction:: Apolar, aliphatic (Gly, Ala, Val, Leu, Ile, Abu, Ival)
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: DVFSVAGNIK
Nearest Stachelhaus code(s):: Ala DVFSVALVYK (62% 8� match)
Stachelhaus code match:: 70% (weak)

AMP-binding (2927..3333): X

nrpys: (unknown)

SVM prediction details:

Predicted physicochemical class:: N/A
Large clusters prediction:: N/A
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: DVLDIGGIGK
Nearest Stachelhaus code(s):: nDodec DVLFIGGVAK (53% 8� match)
Stachelhaus code match:: 70% (weak)

scaffold_60 - Region 1 - NRPS

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Location: 1 - 40,703 nt. (total: 40,703 nt) Show pHMM detection rules used

Region on contig edge.

NRPS: cds(Condensation and (AMP-binding or A-OX))

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Predicted core structure(s)

For candidate cluster 1, location 0 - 40703:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (X - X)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

2150351

AMP-binding (265..643): X

nrpys: Asp, Asn, Glu, Gln, Aad

SVM prediction details:

Predicted physicochemical class:: hydrophilic (Arg, Asp, Glu, Asn, Lys, Gln, Orn, Aad)
Large clusters prediction:: Aliphatic chain with H-bond donor (Asp, Asn, Glu, Gln, Aad)
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: SARENGAQMK
Nearest Stachelhaus code(s):
Stachelhaus code match:: 0% (weak)

AMP-binding (1289..1676): X

nrpys: Ala, Gly, Val, Leu, Ile, Abu, Ival, Ser, Thr, Hpg, Dhpg, Cys, Pro, Hpr

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic (Ala, Gly, Val, Leu, Ile, Abu, Ival, Ser, Thr, Hpg, Dhpg, Cys, Pro, Hpr)
Large clusters prediction:: N/A
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: DAYMNCGILK
Nearest Stachelhaus code(s):: Val DAWMFAAILK (50% 8� match)
Stachelhaus code match:: 60% (weak)

scaffold_618 - Region 1 - terpene

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Location: 1 - 24,977 nt. (total: 24,977 nt) Show pHMM detection rules used

Region on contig edge.

terpene: (Terpene_synth or Terpene_synth_C or phytoene_synt or Lycopene_cycl or terpene_cyclase or NapT7 or fung_ggpps or fung_ggpps2 or trichodiene_synth or TRI5)

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scaffold_62 - Region 1 - NRPS-like

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Location: 1 - 39,861 nt. (total: 39,861 nt) Show pHMM detection rules used

Region on contig edge.

NRPS-like: cds((PP-binding or NAD_binding_4) and (AMP-binding or A-OX))

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No matches found.

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NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 1, location 0 - 39861:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (X)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

2376046

AMP-binding (72..485): X

nrpys: Ala, Gly, Val, Leu, Ile, Abu, Ival, Ser, Thr, Hpg, Dhpg, Cys, Pro, Hpr

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic (Ala, Gly, Val, Leu, Ile, Abu, Ival, Ser, Thr, Hpg, Dhpg, Cys, Pro, Hpr)
Large clusters prediction:: N/A
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: IALISSTLLK
Nearest Stachelhaus code(s):
Stachelhaus code match:: 0% (weak)

scaffold_63 - Region 1 - fungal-RiPP-like

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Location: 63,122 - 145,664 nt. (total: 82,543 nt) Show pHMM detection rules used

Region on contig edge.

fungal-RiPP-like: DUF3328

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scaffold_66 - Region 1 - NRPS-like,T1PKS

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Location: 1 - 67,017 nt. (total: 67,017 nt) Show pHMM detection rules used

Region on contig edge.

T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))
NRPS-like: cds((PP-binding or NAD_binding_4) and (AMP-binding or A-OX))

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Predicted core structure(s)

For candidate cluster 1, location 0 - 67017:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (redmal) + (Gly)

Direct lookup in NORINE database: strict or relaxed

For candidate cluster 2, location 0 - 61614:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (redmal) + (Gly)

Direct lookup in NORINE database: strict or relaxed

For candidate cluster 3, location 3464 - 67017:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (redmal) + (Gly)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

1558257

PKS_AT (520..833): mal

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 79.2%; Methylmalonyl-CoA: 62.5%; Isobutyryl-CoA: 54.2%

minowa: Isobutyryl-CoA

Prediction, score:

Isobutyryl-CoA: 81.8
Methylmalonyl-CoA: 80.2
Methoxymalonyl-CoA: 77.2
Malonyl-CoA: 62.6
Ethylmalonyl-CoA: 39.4
Propionyl-CoA: 38.0
Benzoyl-CoA: 36.6
inactive: 35.1
3-Methylbutyryl-CoA: 33.6
trans-1,2-CPDA: 27.4
2-Methylbutyryl-CoA: 25.1
fatty_acid: 14.1
Acetyl-CoA: 12.7
CHC-CoA: 8.8

1555861

Search NORINE for peptide: strict or relaxed

AMP-binding (117..530): Gly

nrpys: Gly

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic (Ala, Gly, Val, Leu, Ile, Abu, Ival, Ser, Thr, Hpg, Dhpg, Cys, Pro, Hpr)
Large clusters prediction:: N/A
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: DLVYFATVQK
Nearest Stachelhaus code(s):: Gly DLVYFATVQK (85% 8� match)
Stachelhaus code match:: 100% (strong)

scaffold_69 - Region 1 - T1PKS,terpene

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Location: 14,509 - 100,585 nt. (total: 86,077 nt) Show pHMM detection rules used

terpene: (Terpene_synth or Terpene_synth_C or phytoene_synt or Lycopene_cycl or terpene_cyclase or NapT7 or fung_ggpps or fung_ggpps2 or trichodiene_synth or TRI5)
T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))

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No matches found.

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NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 1, location 14508 - 100585:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (pk)

Direct lookup in NORINE database: strict or relaxed

For candidate cluster 3, location 32763 - 100585:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (pk)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

2104880

PKS_AT (610..914): pk

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 79.2%; Methylmalonyl-CoA: 66.7%; Methoxymalonyl-CoA: 58.3%

minowa: Methylmalonyl-CoA

Prediction, score:

Methylmalonyl-CoA: 91.2
Methoxymalonyl-CoA: 79.7
Malonyl-CoA: 56.3
Isobutyryl-CoA: 54.2
Propionyl-CoA: 41.5
Benzoyl-CoA: 38.5
trans-1,2-CPDA: 33.0
fatty_acid: 20.9
CHC-CoA: 17.3
2-Methylbutyryl-CoA: 16.0
inactive: 12.2
3-Methylbutyryl-CoA: 10.8
Acetyl-CoA: 8.4
Ethylmalonyl-CoA: -2.2

scaffold_7 - Region 1 - fungal-RiPP-like

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Location: 1 - 64,252 nt. (total: 64,252 nt) Show pHMM detection rules used

Region on contig edge.

fungal-RiPP-like: DUF3328

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scaffold_70 - Region 1 - indole

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Location: 86,682 - 117,785 nt. (total: 31,104 nt) Show pHMM detection rules used

indole: (indsynth or dmat or indole_PTase)

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scaffold_711 - Region 1 - terpene

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Location: 1 - 20,700 nt. (total: 20,700 nt) Show pHMM detection rules used

Region on contig edge.

terpene: (Terpene_synth or Terpene_synth_C or phytoene_synt or Lycopene_cycl or terpene_cyclase or NapT7 or fung_ggpps or fung_ggpps2 or trichodiene_synth or TRI5)

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scaffold_79 - Region 1 - fungal-RiPP-like

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Location: 32,469 - 123,601 nt. (total: 91,133 nt) Show pHMM detection rules used

fungal-RiPP-like: DUF3328

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scaffold_804 - Region 1 - T1PKS

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Location: 1 - 16,570 nt. (total: 16,570 nt) Show pHMM detection rules used

Region on contig edge.

T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))

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Predicted core structure(s)

For candidate cluster 1, location 0 - 16570:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (pk)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

2160465

PKS_AT (553..865): pk

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 83.3%; Methylmalonyl-CoA: 62.5%; Isobutyryl-CoA: 62.5%

minowa: Methylmalonyl-CoA

Prediction, score:

Methylmalonyl-CoA: 90.7
Methoxymalonyl-CoA: 86.0
Malonyl-CoA: 67.3
Isobutyryl-CoA: 65.8
Propionyl-CoA: 47.3
Ethylmalonyl-CoA: 45.1
Benzoyl-CoA: 39.0
inactive: 38.5
2-Methylbutyryl-CoA: 29.6
3-Methylbutyryl-CoA: 21.9
trans-1,2-CPDA: 20.4
CHC-CoA: 12.6
fatty_acid: 12.5
Acetyl-CoA: 12.2

2305362

AMP-binding (48..492): X

nrpys: Val, Leu, Ile, Abu, Ival

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic (Ala, Gly, Val, Leu, Ile, Abu, Ival, Ser, Thr, Hpg, Dhpg, Cys, Pro, Hpr)
Large clusters prediction:: N/A
Small clusters prediction:: Aliphatic, branched hydrophobic (Val, Leu, Ile, Abu, Ival)
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: GSGYISCPVK
Nearest Stachelhaus code(s):
Stachelhaus code match:: 0% (weak)

scaffold_81 - Region 1 - T1PKS

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Location: 62,382 - 128,945 nt. (total: 66,564 nt) Show pHMM detection rules used

Region on contig edge.

T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))

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Predicted core structure(s)

For candidate cluster 1, location 62381 - 128945:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (pk)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

2356032

PKS_AT (891..1181): pk

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 54.2%

minowa: Methoxymalonyl-CoA

Prediction, score:

Methoxymalonyl-CoA: 45.7
Malonyl-CoA: 40.5
Methylmalonyl-CoA: 34.2
trans-1,2-CPDA: 16.1
CHC-CoA: 15.3
inactive: 15.2
Ethylmalonyl-CoA: 14.4
Propionyl-CoA: 14.1
2-Methylbutyryl-CoA: 9.4
fatty_acid: 9.2
Benzoyl-CoA: 9.2
Isobutyryl-CoA: 0.0
Acetyl-CoA: 0.0
3-Methylbutyryl-CoA: 0.0

scaffold_813 - Region 1 - fungal-RiPP-like

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Location: 1 - 16,261 nt. (total: 16,261 nt) Show pHMM detection rules used

Region on contig edge.

fungal-RiPP-like: DUF3328

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scaffold_817 - Region 1 - T1PKS

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Location: 1 - 16,101 nt. (total: 16,101 nt) Show pHMM detection rules used

Region on contig edge.

T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))

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Predicted core structure(s)

For candidate cluster 1, location 0 - 16101:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (pk)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

2130329

PKS_AT (531..843): pk

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 75.0%; Methylmalonyl-CoA: 62.5%; Methoxymalonyl-CoA: 58.3%

minowa: Methylmalonyl-CoA

Prediction, score:

Methylmalonyl-CoA: 68.4
Methoxymalonyl-CoA: 63.6
Ethylmalonyl-CoA: 37.1
Isobutyryl-CoA: 32.3
Malonyl-CoA: 24.9
Benzoyl-CoA: 24.0
trans-1,2-CPDA: 22.5
Propionyl-CoA: 18.2
fatty_acid: 15.8
3-Methylbutyryl-CoA: 10.5
CHC-CoA: 10.3
2-Methylbutyryl-CoA: 7.8
inactive: 0.0
Acetyl-CoA: 0.0

scaffold_84 - Region 1 - fungal-RiPP-like

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Location: 10,142 - 123,891 nt. (total: 113,750 nt) Show pHMM detection rules used

fungal-RiPP-like: DUF3328

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scaffold_86 - Region 1 - NRPS,T1PKS

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Location: 36,807 - 125,685 nt. (total: 88,879 nt) Show pHMM detection rules used

Region on contig edge.

NRPS: cds(Condensation and (AMP-binding or A-OX))
T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))

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Predicted core structure(s)

For candidate cluster 1, location 36806 - 125685:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (pk) + (X - Leu - Val - Tyr - X)

Direct lookup in NORINE database: strict or relaxed

For candidate cluster 2, location 36806 - 114329:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (pk) + (X - Leu - Val - Tyr - X)

Direct lookup in NORINE database: strict or relaxed

For candidate cluster 3, location 71868 - 125685:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (pk) + (X - Leu - Val - Tyr - X)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

2217287

Search NORINE for peptide: strict or relaxed

AMP-binding (317..718): X

nrpys: Gly, Ala

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic (Ala, Gly, Val, Leu, Ile, Abu, Ival, Ser, Thr, Hpg, Dhpg, Cys, Pro, Hpr)
Large clusters prediction:: Apolar, aliphatic (Gly, Ala, Val, Leu, Ile, Abu, Ival)
Small clusters prediction:: Tiny, hydrophilic, transition to aliphatic (Gly, Ala)
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: DIGCVCAILK
Nearest Stachelhaus code(s):: Leu DIHFVGAIAK (59% 8� match); Hpg DIWHVGAITK (47% 8� match)
Stachelhaus code match:: 60% (weak)

AMP-binding (1401..1812): Leu

nrpys: Leu

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic (Ala, Gly, Val, Leu, Ile, Abu, Ival, Ser, Thr, Hpg, Dhpg, Cys, Pro, Hpr)
Large clusters prediction:: N/A
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: DILLLGAVVK
Nearest Stachelhaus code(s):: Leu DALLLGAVVK (59% 8� match)
Stachelhaus code match:: 90% (moderate)

AMP-binding (2501..2899): Val

nrpys: Val

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic (Ala, Gly, Val, Leu, Ile, Abu, Ival, Ser, Thr, Hpg, Dhpg, Cys, Pro, Hpr)
Large clusters prediction:: Apolar, aliphatic (Gly, Ala, Val, Leu, Ile, Abu, Ival)
Small clusters prediction:: Aliphatic, branched hydrophobic (Val, Leu, Ile, Abu, Ival)
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: DALFVGGIFK
Nearest Stachelhaus code(s):: Val DAMFVGGVFK (56% 8� match)
Stachelhaus code match:: 80% (moderate)

AMP-binding (3577..3971): Tyr

nrpys: Tyr

SVM prediction details:

Predicted physicochemical class:: N/A
Large clusters prediction:: N/A
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: DALALGMVVK
Nearest Stachelhaus code(s):: Tyr DALAVGEVVK (50% 8� match)
Stachelhaus code match:: 80% (moderate)

AMP-binding (4667..5062): X

nrpys: Val, Leu, Ile, Abu, Ival

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic (Ala, Gly, Val, Leu, Ile, Abu, Ival, Ser, Thr, Hpg, Dhpg, Cys, Pro, Hpr)
Large clusters prediction:: N/A
Small clusters prediction:: Aliphatic, branched hydrophobic (Val, Leu, Ile, Abu, Ival)
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: GAAFIGGTIK
Nearest Stachelhaus code(s):: Val DALFIGGTFK (44% 8� match); Leu or Ile DALFIGGTFK (44% 8� match)
Stachelhaus code match:: 70% (weak)

2151299

PKS_AT (517..820): pk

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 75.0%; Methylmalonyl-CoA: 62.5%; Propionyl-CoA: 58.3%

minowa: Methylmalonyl-CoA

Prediction, score:

Methylmalonyl-CoA: 83.3
Methoxymalonyl-CoA: 63.6
Propionyl-CoA: 51.8
Malonyl-CoA: 41.7
fatty_acid: 38.5
Isobutyryl-CoA: 32.7
Benzoyl-CoA: 26.7
2-Methylbutyryl-CoA: 25.0
trans-1,2-CPDA: 23.5
CHC-CoA: 21.1
3-Methylbutyryl-CoA: 10.5
Acetyl-CoA: 5.7
inactive: 0.0
Ethylmalonyl-CoA: -4.2

scaffold_865 - Region 1 - NRPS

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Location: 1 - 13,800 nt. (total: 13,800 nt) Show pHMM detection rules used

Region on contig edge.

NRPS: cds(Condensation and (AMP-binding or A-OX))

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Predicted core structure(s)

For candidate cluster 1, location 0 - 13800:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (Phe)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

1796601

Search NORINE for peptide: strict or relaxed

AMP-binding (625..1009): Phe

nrpys: Phe

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aromatic (Phe, Tyr, diOH-Bz, Ph-Gly, bOH-Tyr)
Large clusters prediction:: Aromatic side chain (Phe, Trp, Ph-Gly, Tyr, bOH-Tyr)
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: DGHIYVMCGK
Nearest Stachelhaus code(s):: Phe DGHIYVMCGK (91% 8� match)
Stachelhaus code match:: 100% (strong)

scaffold_87 - Region 1 - fungal-RiPP-like

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Location: 1 - 58,400 nt. (total: 58,400 nt) Show pHMM detection rules used

Region on contig edge.

fungal-RiPP-like: DUF3328

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scaffold_88 - Region 1 - T1PKS

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Location: 60,803 - 124,025 nt. (total: 63,223 nt) Show pHMM detection rules used

Region on contig edge.

T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))

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Predicted core structure(s)

For candidate cluster 1, location 60802 - 124025:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (pk)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

2106496

PKS_AT (913..1206): pk

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 62.5%; Ethylmalonyl-CoA: 58.3%; Methylmalonyl-CoA: 58.3%

minowa: Methoxymalonyl-CoA

Prediction, score:

Methoxymalonyl-CoA: 54.1
inactive: 53.6
Methylmalonyl-CoA: 46.1
Malonyl-CoA: 36.8
Propionyl-CoA: 28.5
CHC-CoA: 26.5
Ethylmalonyl-CoA: 22.7
2-Methylbutyryl-CoA: 18.9
fatty_acid: 18.1
trans-1,2-CPDA: 17.9
Acetyl-CoA: 17.8
Benzoyl-CoA: 15.4
3-Methylbutyryl-CoA: 14.1
Isobutyryl-CoA: 12.8

scaffold_892 - Region 1 - T1PKS

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Location: 1 - 12,645 nt. (total: 12,645 nt) Show pHMM detection rules used

Region on contig edge.

T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))

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Predicted core structure(s)

For candidate cluster 1, location 0 - 12645:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (mal)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

2131061

PKS_AT (928..1226): mal

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 75.0%; inactive: 62.5%; Methylmalonyl-CoA: 54.2%

minowa: Malonyl-CoA

Prediction, score:

Malonyl-CoA: 101.2
inactive: 77.1
Methylmalonyl-CoA: 58.9
Methoxymalonyl-CoA: 48.3
Propionyl-CoA: 41.3
Benzoyl-CoA: 22.3
fatty_acid: 21.7
2-Methylbutyryl-CoA: 20.7
Isobutyryl-CoA: 18.6
CHC-CoA: 18.4
Ethylmalonyl-CoA: 17.8
trans-1,2-CPDA: 15.1
Acetyl-CoA: 12.0
3-Methylbutyryl-CoA: 9.2

scaffold_91 - Region 1 - indole

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Location: 71,056 - 102,258 nt. (total: 31,203 nt) Show pHMM detection rules used

indole: (indsynth or dmat or indole_PTase)

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scaffold_94 - Region 1 - T1PKS

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Location: 40,049 - 106,403 nt. (total: 66,355 nt) Show pHMM detection rules used

T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))

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Predicted core structure(s)

For candidate cluster 1, location 40048 - 106403:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (mal)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

2443527

PKS_AT (512..807): mal

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 54.2%

minowa: inactive

Prediction, score:

inactive: 52.7
Malonyl-CoA: 52.3
Methoxymalonyl-CoA: 50.0
Methylmalonyl-CoA: 43.1
Ethylmalonyl-CoA: 28.2
Propionyl-CoA: 28.0
CHC-CoA: 25.5
2-Methylbutyryl-CoA: 19.1
trans-1,2-CPDA: 17.4
Isobutyryl-CoA: 15.9
Benzoyl-CoA: 14.5
3-Methylbutyryl-CoA: 12.5
Acetyl-CoA: 12.3
fatty_acid: 11.7

scaffold_959 - Region 1 - fungal-RiPP-like

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Location: 1 - 10,251 nt. (total: 10,251 nt) Show pHMM detection rules used

Region on contig edge.

fungal-RiPP-like: DUF3328

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scaffold_96 - Region 1 - NRPS-like

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Location: 47,318 - 110,669 nt. (total: 63,352 nt) Show pHMM detection rules used

NRPS-like: cds((PP-binding or NAD_binding_4) and (AMP-binding or A-OX))

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Predicted core structure(s)

For candidate cluster 1, location 47317 - 110669:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (X)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

2107203

AMP-binding (36..440): X

nrpys: Ala, Gly, Val, Leu, Ile, Abu, Ival, Ser, Thr, Hpg, Dhpg, Cys, Pro, Hpr

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic (Ala, Gly, Val, Leu, Ile, Abu, Ival, Ser, Thr, Hpg, Dhpg, Cys, Pro, Hpr)
Large clusters prediction:: N/A
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: GGFFTAIAVK
Nearest Stachelhaus code(s):: Ile or Val DGLFVGIAVK (35% 8� match)
Stachelhaus code match:: 60% (weak)

scaffold_98 - Region 1 - T1PKS

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Location: 13,509 - 81,836 nt. (total: 68,328 nt) Show pHMM detection rules used

T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))

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core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

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Gene details

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Gene overview

NRPS/PKS domains

KnownClusterBlast

NRPS/PKS modules

Gene/CDS overview

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Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

Detailed domain annotation

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Similar known gene clusters from MIBiG 3.1

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NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 1, location 13508 - 81836:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (pk)

Direct lookup in NORINE database: strict or relaxed

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NRPS/PKS monomer predictions

2377166

PKS_AT (567..878): pk

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 79.2%; Methylmalonyl-CoA: 66.7%; 2-Methylbutyryl-CoA: 58.3%

minowa: Methylmalonyl-CoA

Prediction, score:

Methylmalonyl-CoA: 71.9
Methoxymalonyl-CoA: 61.7
Malonyl-CoA: 52.7
Ethylmalonyl-CoA: 31.9
Propionyl-CoA: 30.4
trans-1,2-CPDA: 22.1
fatty_acid: 18.4
Acetyl-CoA: 14.8
Isobutyryl-CoA: 14.7
2-Methylbutyryl-CoA: 14.7
Benzoyl-CoA: 13.1
CHC-CoA: 11.0
inactive: 10.8
3-Methylbutyryl-CoA: 8.7