Acarospora strigata CBS 132363

Identified secondary metabolite regions using strictness 'relaxed'

scaffold_1025

Region	Type	From	To	Most similar known cluster		Similarity
Region 8.1	T1PKS	1	19,075	burnettiene A/preburnettiene B/preburnettiene A	Polyketide	37%

scaffold_11056

Region	Type	From	To	Most similar known cluster		Similarity
Region 19.1	fungal-RiPP	9,868	68,679

scaffold_11468

Region	Type	From	To	Most similar known cluster		Similarity
Region 27.1	T1PKS,NRPS-like	1	120,370	leucinostatin A/leucinostatin B	NRP+Polyketide	10%

scaffold_1381

Region	Type	From	To	Most similar known cluster		Similarity
Region 75.1	NRPS-like	1	35,311

scaffold_14549

Region	Type	From	To	Most similar known cluster		Similarity
Region 96.1	NRPS	1	18,152	gliovirin	NRP	37%

scaffold_14671

Region	Type	From	To	Most similar known cluster		Similarity
Region 100.1	T1PKS	25,498	93,795	phomopsin A/phomopsin B/phomopsin E	RiPP	9%

scaffold_15056

Region	Type	From	To	Most similar known cluster		Similarity
Region 114.1	fungal-RiPP-like	64,662	155,098

scaffold_15185

Region	Type	From	To	Most similar known cluster		Similarity
Region 119.1	fungal-RiPP-like,T3PKS	1	56,727

scaffold_16232

Region	Type	From	To	Most similar known cluster		Similarity
Region 167.1	T1PKS	1	52,526	4-epi-15-epi-brefeldin A	Polyketide:Iterative type I polyketide	20%

scaffold_16250

Region	Type	From	To	Most similar known cluster		Similarity
Region 168.1	NRPS	255,326	335,750	cyclo-(D-Phe-L-Phe-D-Val-L-Val)/cyclo-(D-Tyr-L-Phe-D-Val-L-Val)/cyclo-(D-Tyr-L-Trp-D-Val-L-Val)/cyclo-(D-Phe-L-Trp-D-Val-L-Val)/cyclo-(D-Phe-L-Phe-D-Val-L-Ile)/cyclo-(D-Phe-L-Phe-D-Ile-L-Val)/cyclo-(D-Tyr-L-Trp-D-Val-L-Ile)/cyclo-(D-Tyr-L-Trp-D-Ile-L-Val)/cyclo-(D-Tyr-L-Phe-D-Val-L-Ile)/cyclo-(D-Tyr-L-Phe-D-Ile-L-Val)	NRP:Cyclic depsipeptide	100%

scaffold_1754

Region	Type	From	To	Most similar known cluster		Similarity
Region 190.1	T1PKS	1	40,738	zopfiellin	Polyketide	25%

scaffold_18802

Region	Type	From	To	Most similar known cluster		Similarity
Region 219.1	T1PKS	2,212	54,534	solanapyrone A	Polyketide	40%

scaffold_19942

Region	Type	From	To	Most similar known cluster		Similarity
Region 245.1	T1PKS	1	46,758

scaffold_201

Region	Type	From	To	Most similar known cluster		Similarity
Region 254.1	terpene	1	16,401	clavaric acid	Terpene	100%

scaffold_20175

Region	Type	From	To	Most similar known cluster		Similarity
Region 257.1	NRPS-like	6,301	50,005

scaffold_23089

Region	Type	From	To	Most similar known cluster		Similarity
Region 306.1	T1PKS	1	41,185

scaffold_23875

Region	Type	From	To	Most similar known cluster		Similarity
Region 320.1	fungal-RiPP-like	1	65,792

scaffold_257

Region	Type	From	To	Most similar known cluster		Similarity
Region 348.1	T1PKS	1	65,723

scaffold_25848

Region	Type	From	To	Most similar known cluster		Similarity
Region 351.1	T1PKS	21,870	90,246

scaffold_269

Region	Type	From	To	Most similar known cluster		Similarity
Region 354.1	T1PKS	1	48,359	1,3,6,8-tetrahydroxynaphthalene	Polyketide	100%

scaffold_2928

Region	Type	From	To	Most similar known cluster		Similarity
Region 369.1	fungal-RiPP-like	1	25,783

scaffold_2955

Region	Type	From	To	Most similar known cluster		Similarity
Region 374.1	NRPS	1	26,381	destruxin A	NRP	28%

scaffold_3086

Region	Type	From	To	Most similar known cluster		Similarity
Region 387.1	terpene	31,277	70,348	paxilline/paspaline/13-dehydroxypaxilline/paspaline B	Terpene	75%

scaffold_3113

Region	Type	From	To	Most similar known cluster		Similarity
Region 395.1	fungal-RiPP-like	26,799	102,334

scaffold_3213

Region	Type	From	To	Most similar known cluster		Similarity
Region 406.1	terpene	1	29,042	squalestatin S1	Terpene	40%

scaffold_3284

Region	Type	From	To	Most similar known cluster		Similarity
Region 410.1	T1PKS	1	33,561

scaffold_3547

Region	Type	From	To	Most similar known cluster		Similarity
Region 429.1	fungal-RiPP-like	45,537	136,095

scaffold_4465

Region	Type	From	To	Most similar known cluster		Similarity
Region 471.1	terpene	1	23,907

scaffold_4700

Region	Type	From	To	Most similar known cluster		Similarity
Region 488.1	T1PKS	1	62,059	tricholignan A	Polyketide:Iterative type I polyketide	22%

scaffold_4873

Region	Type	From	To	Most similar known cluster		Similarity
Region 502.1	fungal-RiPP-like	1	17,005

scaffold_5370

Region	Type	From	To	Most similar known cluster		Similarity
Region 528.1	NRPS	1	50,448

scaffold_541

Region	Type	From	To	Most similar known cluster		Similarity
Region 529.1	T1PKS	1	58,630	compactin	Polyketide	33%

scaffold_5626

Region	Type	From	To	Most similar known cluster		Similarity
Region 539.1	NRPS,T1PKS	1	47,396	phyllostictine A/phyllostictine B	NRP+Polyketide	50%

scaffold_6978

Region	Type	From	To	Most similar known cluster		Similarity
Region 597.1	T1PKS	90,803	139,919

scaffold_7007

Region	Type	From	To	Most similar known cluster		Similarity
Region 599.1	NRPS,T1PKS	1	37,359

scaffold_7455

Region	Type	From	To	Most similar known cluster		Similarity
Region 629.1	T1PKS,NRPS-like	24,291	92,765	2,4-dihydroxy-5,6-dimethyl benzaldehyde	Polyketide	28%

scaffold_7474

Region	Type	From	To	Most similar known cluster		Similarity
Region 630.1	NRPS-like,T1PKS	1	45,100

scaffold_7545

Region	Type	From	To	Most similar known cluster		Similarity
Region 634.1	terpene	40,504	75,102

scaffold_8394

Region	Type	From	To	Most similar known cluster		Similarity
Region 673.1	NRPS,transAT-PKS,T1PKS	73,840	180,708

scaffold_8592

Region	Type	From	To	Most similar known cluster		Similarity
Region 686.1	indole	1	24,716

scaffold_8699

Region	Type	From	To	Most similar known cluster		Similarity
Region 695.1	T1PKS	1	72,513	azanigerone A/azanigerone B/azanigerone C/azanigerone D/azanigerone E/azanigerone F	Polyketide	46%

scaffold_8982

Region	Type	From	To	Most similar known cluster		Similarity
Region 716.1	NRPS,indole	33,412	97,968	sirodesmin PL	NRP	16%

No secondary metabolite regions were found in these records:: scaffold_1; scaffold_10008; scaffold_10009; scaffold_10011; scaffold_10013; scaffold_10023; scaffold_10031; scaffold_10426; scaffold_10492; scaffold_1060; scaffold_10647; scaffold_10657; scaffold_1075; scaffold_10813; scaffold_10832; scaffold_10840; scaffold_10911; scaffold_1106; scaffold_1113; scaffold_11198; scaffold_1121; scaffold_11262; scaffold_11324; scaffold_1137; scaffold_1149; scaffold_1163; scaffold_1165; scaffold_1170; scaffold_1171; scaffold_1172; scaffold_1188; scaffold_1189; scaffold_11924; scaffold_11989; scaffold_1205; scaffold_1212; scaffold_1214; scaffold_12141; scaffold_12176; scaffold_1224; scaffold_12294; scaffold_12350; scaffold_12550; scaffold_12577; scaffold_12578; scaffold_1267; scaffold_1268; scaffold_1269; scaffold_12760; scaffold_12842; scaffold_1292; scaffold_12922; scaffold_1293; scaffold_12947; scaffold_13016; scaffold_13135; scaffold_1320; scaffold_13204; scaffold_13205; scaffold_13299; scaffold_13328; scaffold_1336; scaffold_1338; scaffold_13425; scaffold_13447; scaffold_13499; scaffold_13546; scaffold_13583; scaffold_13591; scaffold_13730; scaffold_13773; scaffold_1385; scaffold_13876; scaffold_13896; scaffold_13912; scaffold_1392; scaffold_13935; scaffold_1394; scaffold_13975; scaffold_14001; scaffold_14029; scaffold_14055; scaffold_14067; scaffold_1426; scaffold_1429; scaffold_1434; scaffold_14416; scaffold_14420; scaffold_14436; scaffold_14470; scaffold_145; scaffold_14570; scaffold_146; scaffold_14601; scaffold_1469; scaffold_14719; scaffold_14736; scaffold_148; scaffold_14815; scaffold_14845; scaffold_14851; scaffold_1488; scaffold_14903; scaffold_1493; scaffold_14968; scaffold_14984; scaffold_150; scaffold_15077; scaffold_151; scaffold_15161; scaffold_15168; scaffold_15186; scaffold_15228; scaffold_15306; scaffold_15311; scaffold_15317; scaffold_15343; scaffold_15385; scaffold_15389; scaffold_15493; scaffold_15556; scaffold_15568; scaffold_15608; scaffold_15651; scaffold_15657; scaffold_15674; scaffold_15693; scaffold_15696; scaffold_15709; scaffold_15743; scaffold_15748; scaffold_15754; scaffold_1577; scaffold_158; scaffold_15814; scaffold_15820; scaffold_15839; scaffold_15843; scaffold_15878; scaffold_1590; scaffold_15902; scaffold_1592; scaffold_15929; scaffold_15936; scaffold_15939; scaffold_1600; scaffold_16039; scaffold_16044; scaffold_16048; scaffold_16087; scaffold_16089; scaffold_16098; scaffold_16151; scaffold_16159; scaffold_16183; scaffold_16192; scaffold_16209; scaffold_1621; scaffold_16256; scaffold_16281; scaffold_16283; scaffold_16316; scaffold_16329; scaffold_16346; scaffold_16364; scaffold_16380; scaffold_164; scaffold_16432; scaffold_16439; scaffold_1655; scaffold_1665; scaffold_16680; scaffold_16834; scaffold_1686; scaffold_16941; scaffold_170; scaffold_17066; scaffold_17266; scaffold_17455; scaffold_1756; scaffold_1763; scaffold_17719; scaffold_17744; scaffold_17758; scaffold_1777; scaffold_17777; scaffold_17835; scaffold_17869; scaffold_1798; scaffold_1799; scaffold_180; scaffold_18052; scaffold_1806; scaffold_18178; scaffold_18245; scaffold_1832; scaffold_18481; scaffold_185; scaffold_1855; scaffold_18563; scaffold_186; scaffold_1864; scaffold_18650; scaffold_18726; scaffold_18752; scaffold_1877; scaffold_1879; scaffold_1886; scaffold_1895; scaffold_1897; scaffold_190; scaffold_1901; scaffold_19020; scaffold_19039; scaffold_1906; scaffold_19115; scaffold_19131; scaffold_1920; scaffold_1929; scaffold_19292; scaffold_1930; scaffold_19368; scaffold_19369; scaffold_19479; scaffold_19609; scaffold_19618; scaffold_19631; scaffold_19655; scaffold_19673; scaffold_19716; scaffold_19832; scaffold_19909; scaffold_19967; scaffold_2; scaffold_20; scaffold_200; scaffold_20003; scaffold_20023; scaffold_2006; scaffold_20078; scaffold_20106; scaffold_20145; scaffold_2019; scaffold_202; scaffold_20208; scaffold_20233; scaffold_20235; scaffold_20280; scaffold_20286; scaffold_20335; scaffold_2034; scaffold_204; scaffold_2042; scaffold_20457; scaffold_20466; scaffold_20541; scaffold_20593; scaffold_20595; scaffold_206; scaffold_20604; scaffold_20618; scaffold_20626; scaffold_2067; scaffold_207; scaffold_2072; scaffold_2087; scaffold_2089; scaffold_209; scaffold_2090; scaffold_21052; scaffold_2109; scaffold_2126; scaffold_21362; scaffold_2142; scaffold_2143; scaffold_2144; scaffold_215; scaffold_2151; scaffold_21748; scaffold_22; scaffold_2201; scaffold_2209; scaffold_2224; scaffold_22367; scaffold_2245; scaffold_22460; scaffold_22538; scaffold_22833; scaffold_2287; scaffold_23; scaffold_23090; scaffold_23135; scaffold_2317; scaffold_23253; scaffold_2334; scaffold_23430; scaffold_2344; scaffold_2347; scaffold_23637; scaffold_2370; scaffold_2371; scaffold_2372; scaffold_2384; scaffold_2396; scaffold_23973; scaffold_23994; scaffold_23999; scaffold_24; scaffold_24054; scaffold_2418; scaffold_242; scaffold_24228; scaffold_243; scaffold_2438; scaffold_244; scaffold_2444; scaffold_2445; scaffold_2446; scaffold_2447; scaffold_245; scaffold_248; scaffold_2492; scaffold_251; scaffold_2530; scaffold_2545; scaffold_2546; scaffold_25472; scaffold_255; scaffold_2565; scaffold_2567; scaffold_258; scaffold_2581; scaffold_2632; scaffold_268; scaffold_27; scaffold_270; scaffold_2755; scaffold_2766; scaffold_278; scaffold_2799; scaffold_2802; scaffold_2811; scaffold_2844; scaffold_2865; scaffold_2886; scaffold_2887; scaffold_2890; scaffold_2909; scaffold_2935; scaffold_2937; scaffold_294; scaffold_295; scaffold_2961; scaffold_2973; scaffold_298; scaffold_2982; scaffold_299; scaffold_2994; scaffold_3013; scaffold_3028; scaffold_3033; scaffold_3075; scaffold_3076; scaffold_3080; scaffold_3088; scaffold_3095; scaffold_3096; scaffold_3097; scaffold_31; scaffold_310; scaffold_3112; scaffold_313; scaffold_3131; scaffold_3156; scaffold_3169; scaffold_3174; scaffold_3176; scaffold_3179; scaffold_318; scaffold_3183; scaffold_32; scaffold_3216; scaffold_3225; scaffold_3233; scaffold_33; scaffold_3301; scaffold_3307; scaffold_3325; scaffold_3341; scaffold_3347; scaffold_335; scaffold_3351; scaffold_3353; scaffold_34; scaffold_3419; scaffold_342; scaffold_3431; scaffold_3449; scaffold_3534; scaffold_3537; scaffold_3538; scaffold_3546; scaffold_36; scaffold_3610; scaffold_3628; scaffold_37; scaffold_371; scaffold_3724; scaffold_378; scaffold_379; scaffold_382; scaffold_383; scaffold_3832; scaffold_384; scaffold_3866; scaffold_3906; scaffold_3969; scaffold_3973; scaffold_3982; scaffold_3983; scaffold_4; scaffold_4035; scaffold_4053; scaffold_4061; scaffold_4122; scaffold_4130; scaffold_418; scaffold_4183; scaffold_419; scaffold_424; scaffold_4252; scaffold_4262; scaffold_4267; scaffold_428; scaffold_4283; scaffold_4293; scaffold_4311; scaffold_4372; scaffold_4390; scaffold_440; scaffold_4427; scaffold_4428; scaffold_4444; scaffold_4504; scaffold_4506; scaffold_4517; scaffold_4522; scaffold_4524; scaffold_453; scaffold_4535; scaffold_4566; scaffold_4574; scaffold_4592; scaffold_4593; scaffold_4615; scaffold_4628; scaffold_4640; scaffold_4673; scaffold_468; scaffold_4701; scaffold_474; scaffold_4743; scaffold_4750; scaffold_4769; scaffold_4790; scaffold_4794; scaffold_4808; scaffold_481; scaffold_4821; scaffold_4822; scaffold_4823; scaffold_4858; scaffold_4874; scaffold_4895; scaffold_4947; scaffold_495; scaffold_5; scaffold_5011; scaffold_502; scaffold_504; scaffold_5073; scaffold_5092; scaffold_5102; scaffold_5116; scaffold_5127; scaffold_5141; scaffold_5149; scaffold_517; scaffold_5171; scaffold_5191; scaffold_5210; scaffold_5233; scaffold_5272; scaffold_528; scaffold_5287; scaffold_5334; scaffold_5336; scaffold_5412; scaffold_542; scaffold_5454; scaffold_546; scaffold_5464; scaffold_547; scaffold_5476; scaffold_55; scaffold_5586; scaffold_5747; scaffold_577; scaffold_5802; scaffold_5817; scaffold_5823; scaffold_5851; scaffold_5859; scaffold_587; scaffold_5887; scaffold_5898; scaffold_5937; scaffold_5962; scaffold_5963; scaffold_597; scaffold_5976; scaffold_598; scaffold_5983; scaffold_5984; scaffold_599; scaffold_6; scaffold_60; scaffold_607; scaffold_6085; scaffold_6097; scaffold_61; scaffold_6102; scaffold_6112; scaffold_6159; scaffold_619; scaffold_62; scaffold_621; scaffold_6275; scaffold_63; scaffold_634; scaffold_6361; scaffold_64; scaffold_6427; scaffold_6486; scaffold_65; scaffold_6528; scaffold_6541; scaffold_6569; scaffold_6571; scaffold_6616; scaffold_6635; scaffold_668; scaffold_673; scaffold_6744; scaffold_6805; scaffold_682; scaffold_683; scaffold_688; scaffold_689; scaffold_6893; scaffold_6909; scaffold_6967; scaffold_6975; scaffold_6999; scaffold_7009; scaffold_7010; scaffold_7018; scaffold_7052; scaffold_7061; scaffold_71; scaffold_7104; scaffold_7145; scaffold_7159; scaffold_7178; scaffold_720; scaffold_7215; scaffold_7217; scaffold_7219; scaffold_7223; scaffold_7276; scaffold_7282; scaffold_73; scaffold_7312; scaffold_7316; scaffold_7341; scaffold_7342; scaffold_7351; scaffold_7359; scaffold_7402; scaffold_741; scaffold_7415; scaffold_742; scaffold_7440; scaffold_7518; scaffold_7521; scaffold_754; scaffold_7549; scaffold_7574; scaffold_7579; scaffold_7595; scaffold_7601; scaffold_7617; scaffold_7621; scaffold_7647; scaffold_7664; scaffold_7670; scaffold_7673; scaffold_7677; scaffold_7711; scaffold_7736; scaffold_7749; scaffold_7821; scaffold_7834; scaffold_788; scaffold_7895; scaffold_7917; scaffold_7928; scaffold_802; scaffold_8025; scaffold_806; scaffold_8102; scaffold_8104; scaffold_8118; scaffold_8153; scaffold_816; scaffold_820; scaffold_8224; scaffold_8235; scaffold_8328; scaffold_8334; scaffold_8359; scaffold_836; scaffold_8383; scaffold_839; scaffold_8409; scaffold_8422; scaffold_8434; scaffold_8437; scaffold_845; scaffold_8456; scaffold_8477; scaffold_848; scaffold_849; scaffold_8511; scaffold_8537; scaffold_855; scaffold_8593; scaffold_8618; scaffold_8657; scaffold_866; scaffold_8660; scaffold_867; scaffold_868; scaffold_8685; scaffold_8744; scaffold_8752; scaffold_8781; scaffold_8813; scaffold_8825; scaffold_8833; scaffold_8838; scaffold_8845; scaffold_8849; scaffold_8859; scaffold_8879; scaffold_8881; scaffold_8909; scaffold_8913; scaffold_8917; scaffold_8918; scaffold_8945; scaffold_895; scaffold_896; scaffold_8972; scaffold_9011; scaffold_9014; scaffold_9041; scaffold_9054; scaffold_9065; scaffold_916; scaffold_917; scaffold_9176; scaffold_918; scaffold_9188; scaffold_919; scaffold_9194; scaffold_9202; scaffold_9231; scaffold_926; scaffold_9275; scaffold_928; scaffold_9294; scaffold_9295; scaffold_9298; scaffold_9340; scaffold_9355; scaffold_9357; scaffold_9371; scaffold_9372; scaffold_9411; scaffold_9439; scaffold_948; scaffold_9489; scaffold_949; scaffold_95; scaffold_9500; scaffold_9513; scaffold_9525; scaffold_9533; scaffold_9537; scaffold_9561; scaffold_9574; scaffold_96; scaffold_9611; scaffold_9624; scaffold_964; scaffold_9663; scaffold_9666; scaffold_968; scaffold_9743; scaffold_9755; scaffold_98; scaffold_9809; scaffold_9824; scaffold_983; scaffold_9838; scaffold_984; scaffold_9847; scaffold_9879; scaffold_9890; scaffold_9910; scaffold_9916; scaffold_9922; scaffold_9941; scaffold_9955; scaffold_9975; scaffold_9999

Compact view

scaffold_1025 - Region 1 - T1PKS

Download region GenBank file

Download region SVG

Location: 1 - 19,075 nt. (total: 19,075 nt) Show pHMM detection rules used

Region on contig edge.

T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

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Gene details

Select a gene to view the details available for it

Gene overview

NRPS/PKS domains

KnownClusterBlast

NRPS/PKS modules

Gene/CDS overview

Filter:

Automatically zoom to filtered/selected features

Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

Detailed domain annotation

Selected features only

Show module domains

Similar known gene clusters from MIBiG 3.1

Module view

Legend

NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 1, location 0 - 19075:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (pk)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

118705

PKS_AT (542..860): pk

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 66.7%; Methylmalonyl-CoA: 62.5%; Methoxymalonyl-CoA: 54.2%

minowa: Methylmalonyl-CoA

Prediction, score:

Methylmalonyl-CoA: 73.6
Methoxymalonyl-CoA: 54.5
Ethylmalonyl-CoA: 50.9
Malonyl-CoA: 32.2
Propionyl-CoA: 27.3
Isobutyryl-CoA: 19.9
Benzoyl-CoA: 16.5
fatty_acid: 15.0
2-Methylbutyryl-CoA: 14.8
CHC-CoA: 8.9
Acetyl-CoA: 8.8
trans-1,2-CPDA: 8.5
3-Methylbutyryl-CoA: 7.9
inactive: 0.0

scaffold_11056 - Region 1 - fungal-RiPP

Download region GenBank file

Download region SVG

Location: 9,868 - 68,679 nt. (total: 58,812 nt) Show pHMM detection rules used

fungal-RiPP: ((pop or ustH) and (p450 or TP_methylase) or DUF3328 and (Peptidase_S41 or Peptidase_S28 or pop or ustH))

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

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zoom to selection

Gene details

Select a gene to view the details available for it

Gene overview

KnownClusterBlast

Gene/CDS overview

Filter:

Automatically zoom to filtered/selected features

Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

Similar known gene clusters from MIBiG 3.1

No matches found.

scaffold_11468 - Region 1 - NRPS-like,T1PKS

Download region GenBank file

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Location: 1 - 120,370 nt. (total: 120,370 nt) Show pHMM detection rules used

Region on contig edge.

T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))
NRPS-like: cds((PP-binding or NAD_binding_4) and (AMP-binding or A-OX))

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

reset view

zoom to selection

Gene details

Select a gene to view the details available for it

Gene overview

NRPS/PKS domains

KnownClusterBlast

NRPS/PKS modules

Gene/CDS overview

Filter:

Automatically zoom to filtered/selected features

Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

Detailed domain annotation

Selected features only

Show module domains

Similar known gene clusters from MIBiG 3.1

Module view

Legend

NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 1, location 0 - 120370:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (pk) + (X)

Direct lookup in NORINE database: strict or relaxed

For candidate cluster 2, location 0 - 60956:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (pk)

Direct lookup in NORINE database: strict or relaxed

For candidate cluster 3, location 57766 - 120370:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (X)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

118921

PKS_AT (598..899): pk

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 66.7%; Methylmalonyl-CoA: 58.3%; Propionyl-CoA: 54.2%

minowa: Methylmalonyl-CoA

Prediction, score:

Methylmalonyl-CoA: 44.4
Methoxymalonyl-CoA: 30.5
Propionyl-CoA: 22.3
Isobutyryl-CoA: 13.3
Benzoyl-CoA: 11.5
trans-1,2-CPDA: 8.9
fatty_acid: 7.5
Malonyl-CoA: 7.4
2-Methylbutyryl-CoA: 0.5
inactive: 0.0
CHC-CoA: 0.0
Acetyl-CoA: 0.0
3-Methylbutyryl-CoA: 0.0
Ethylmalonyl-CoA: -2.9

118947

AMP-binding (93..377): X

nrpys: 4-ohPpa

SVM prediction details:

Predicted physicochemical class:: N/A
Large clusters prediction:: N/A
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: VALFLGGAAK
Nearest Stachelhaus code(s):: 4-ohPpa VALFNGGAGK (59% 8� match)
Stachelhaus code match:: 80% (moderate)

scaffold_1381 - Region 1 - NRPS-like

Download region GenBank file

Download region SVG

Location: 1 - 35,311 nt. (total: 35,311 nt) Show pHMM detection rules used

Region on contig edge.

NRPS-like: cds((PP-binding or NAD_binding_4) and (AMP-binding or A-OX))

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

reset view

zoom to selection

Gene details

Select a gene to view the details available for it

Gene overview

NRPS/PKS domains

KnownClusterBlast

NRPS/PKS modules

Gene/CDS overview

Filter:

Automatically zoom to filtered/selected features

Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

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Selected features only

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No matches found.

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NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 1, location 0 - 35311:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (Aad)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

119385

Search NORINE for peptide: strict or relaxed

AMP-binding (58..528): Aad

nrpys: Aad

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic (Ala, Gly, Val, Leu, Ile, Abu, Ival, Ser, Thr, Hpg, Dhpg, Cys, Pro, Hpr)
Large clusters prediction:: Aliphatic chain with H-bond donor (Asp, Asn, Glu, Gln, Aad)
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: DPRHFVMRAK
Nearest Stachelhaus code(s):: Aad DPRHFVMRAK (94% 8� match)
Stachelhaus code match:: 100% (strong)

scaffold_14549 - Region 1 - NRPS

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Location: 1 - 18,152 nt. (total: 18,152 nt) Show pHMM detection rules used

Region on contig edge.

NRPS: cds(Condensation and (AMP-binding or A-OX))

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Predicted core structure(s)

For candidate cluster 1, location 0 - 18152:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (Phe - Ser)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

119549

Search NORINE for peptide: strict or relaxed

AMP-binding (13..416): Phe

nrpys: Phe

SVM prediction details:

Predicted physicochemical class:: N/A
Large clusters prediction:: N/A
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: DAGALGACAK
Nearest Stachelhaus code(s):: Phe DAGALGACAK (91% 8� match)
Stachelhaus code match:: 100% (strong)

AMP-binding (1062..1442): Ser

nrpys: Ser

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aromatic (Phe, Tyr, diOH-Bz, Ph-Gly, bOH-Tyr)
Large clusters prediction:: N/A
Small clusters prediction:: N/A
Single AA prediction:: tyr (Tyr)

Stachelhaus prediction details:

Stachelhaus sequence:: DYNTYTAICK
Nearest Stachelhaus code(s):: Ser DYNTYTAICK (100% 8� match)
Stachelhaus code match:: 100% (strong)

scaffold_14671 - Region 1 - T1PKS

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Location: 25,498 - 93,795 nt. (total: 68,298 nt) Show pHMM detection rules used

T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))

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Predicted core structure(s)

For candidate cluster 1, location 25497 - 93795:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (mal)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

119637

PKS_AT (936..1223): mal

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 79.2%; Methoxymalonyl-CoA: 58.3%; inactive: 58.3%

minowa: Malonyl-CoA

Prediction, score:

Malonyl-CoA: 124.9
Methoxymalonyl-CoA: 81.0
inactive: 69.1
Methylmalonyl-CoA: 63.2
Isobutyryl-CoA: 41.3
Propionyl-CoA: 35.8
Acetyl-CoA: 31.1
Benzoyl-CoA: 29.6
2-Methylbutyryl-CoA: 29.4
Ethylmalonyl-CoA: 26.8
3-Methylbutyryl-CoA: 21.0
fatty_acid: 20.6
CHC-CoA: 18.5
trans-1,2-CPDA: 12.5

scaffold_15056 - Region 1 - fungal-RiPP-like

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Location: 64,662 - 155,098 nt. (total: 90,437 nt) Show pHMM detection rules used

fungal-RiPP-like: DUF3328

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scaffold_15185 - Region 1 - T3PKS,fungal-RiPP-like

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Location: 1 - 56,727 nt. (total: 56,727 nt) Show pHMM detection rules used

Region on contig edge.

fungal-RiPP-like: DUF3328
T3PKS: (Chal_sti_synt_C or Chal_sti_synt_N)

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scaffold_16232 - Region 1 - T1PKS

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Location: 1 - 52,526 nt. (total: 52,526 nt) Show pHMM detection rules used

Region on contig edge.

T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))

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Predicted core structure(s)

For candidate cluster 1, location 0 - 52526:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (pk)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

120187

PKS_AT (566..858): pk

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 75.0%; Methylmalonyl-CoA: 62.5%; Propionyl-CoA: 58.3%

minowa: Methylmalonyl-CoA

Prediction, score:

Methylmalonyl-CoA: 60.0
Methoxymalonyl-CoA: 52.4
Propionyl-CoA: 25.4
Malonyl-CoA: 24.9
Isobutyryl-CoA: 19.7
2-Methylbutyryl-CoA: 19.7
Ethylmalonyl-CoA: 16.3
trans-1,2-CPDA: 14.2
Benzoyl-CoA: 14.1
inactive: 13.1
fatty_acid: 12.0
3-Methylbutyryl-CoA: 9.6
CHC-CoA: 0.0
Acetyl-CoA: 0.0

scaffold_16250 - Region 1 - NRPS

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Location: 255,326 - 335,750 nt. (total: 80,425 nt) Show pHMM detection rules used

NRPS: cds(Condensation and (AMP-binding or A-OX))

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Predicted core structure(s)

For candidate cluster 1, location 255325 - 335750:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (D-X - X) + (D-X - Leu) + (D-Val)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

120292

Search NORINE for peptide: strict or relaxed

AMP-binding (54..455): Val

nrpys: Val

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic (Ala, Gly, Val, Leu, Ile, Abu, Ival, Ser, Thr, Hpg, Dhpg, Cys, Pro, Hpr)
Large clusters prediction:: Apolar, aliphatic (Gly, Ala, Val, Leu, Ile, Abu, Ival)
Small clusters prediction:: Aliphatic, branched hydrophobic (Val, Leu, Ile, Abu, Ival)
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: DALFVGGVLK
Nearest Stachelhaus code(s):: Val DALFVGIVLK (65% 8� match)
Stachelhaus code match:: 90% (moderate)

120293

Search NORINE for peptide: strict or relaxed

AMP-binding (592..1000): X

nrpys: niCpa

SVM prediction details:

Predicted physicochemical class:: N/A
Large clusters prediction:: N/A
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: DAIIVGGVAK
Nearest Stachelhaus code(s):: niCpa DPIVVGGVAK (44% 8� match)
Stachelhaus code match:: 80% (moderate)

AMP-binding (2159..2564): Leu

nrpys: Leu

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic (Ala, Gly, Val, Leu, Ile, Abu, Ival, Ser, Thr, Hpg, Dhpg, Cys, Pro, Hpr)
Large clusters prediction:: Apolar, aliphatic (Gly, Ala, Val, Leu, Ile, Abu, Ival)
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: DAMLVGAVIK
Nearest Stachelhaus code(s):: Leu DAMLVGAVCK (56% 8� match)
Stachelhaus code match:: 90% (moderate)

120294

AMP-binding (284..679): X

nrpys: (unknown)

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aromatic (Phe, Tyr, diOH-Bz, Ph-Gly, bOH-Tyr)
Large clusters prediction:: Aromatic side chain (Phe, Trp, Ph-Gly, Tyr, bOH-Tyr)
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: DAVVVAGVAK
Nearest Stachelhaus code(s):: oh-D-Kyn DAVVVAGVVK (62% 8� match)
Stachelhaus code match:: 90% (moderate)

AMP-binding (1852..2236): X

nrpys: Arg, Asp, Glu, Asn, Lys, Gln, Orn, Aad

SVM prediction details:

Predicted physicochemical class:: hydrophilic (Arg, Asp, Glu, Asn, Lys, Gln, Orn, Aad)
Large clusters prediction:: N/A
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: DNADGGCINK
Nearest Stachelhaus code(s):: Lys DVAHPGFINK (44% 8� match); Arg DVADVGAIDK (38% 8� match)
Stachelhaus code match:: 60% (weak)

scaffold_1754 - Region 1 - T1PKS

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Location: 1 - 40,738 nt. (total: 40,738 nt) Show pHMM detection rules used

Region on contig edge.

T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))

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Predicted core structure(s)

For candidate cluster 1, location 0 - 40738:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (pk)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

120395

PKS_AT (580..887): pk

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 83.3%; Methylmalonyl-CoA: 66.7%; Ethylmalonyl-CoA: 58.3%

minowa: Methylmalonyl-CoA

Prediction, score:

Methylmalonyl-CoA: 90.1
Methoxymalonyl-CoA: 81.6
Malonyl-CoA: 78.2
Ethylmalonyl-CoA: 65.2
Isobutyryl-CoA: 56.7
Propionyl-CoA: 36.1
Benzoyl-CoA: 28.2
trans-1,2-CPDA: 24.6
3-Methylbutyryl-CoA: 20.4
inactive: 16.9
2-Methylbutyryl-CoA: 12.7
fatty_acid: 11.9
Acetyl-CoA: 10.4
CHC-CoA: 6.9

scaffold_18802 - Region 1 - T1PKS

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Location: 2,212 - 54,534 nt. (total: 52,323 nt) Show pHMM detection rules used

Region on contig edge.

T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))

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Predicted core structure(s)

For candidate cluster 1, location 2211 - 54534:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (pk)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

120691

PKS_AT (644..969): pk

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 70.8%; Methylmalonyl-CoA: 62.5%; Propionyl-CoA: 58.3%

minowa: Methylmalonyl-CoA

Prediction, score:

Methylmalonyl-CoA: 78.1
Methoxymalonyl-CoA: 66.5
Malonyl-CoA: 53.7
Ethylmalonyl-CoA: 43.8
Propionyl-CoA: 43.4
Isobutyryl-CoA: 23.9
trans-1,2-CPDA: 15.5
fatty_acid: 10.7
CHC-CoA: 10.4
2-Methylbutyryl-CoA: 5.7
Benzoyl-CoA: 4.3
Acetyl-CoA: 2.2
inactive: 0.0
3-Methylbutyryl-CoA: 0.0

scaffold_19942 - Region 1 - T1PKS

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Location: 1 - 46,758 nt. (total: 46,758 nt) Show pHMM detection rules used

Region on contig edge.

T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))

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Predicted core structure(s)

For candidate cluster 1, location 0 - 46758:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (pk)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

121045

PKS_AT (578..881): pk

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 79.2%; Methylmalonyl-CoA: 70.8%; Methoxymalonyl-CoA: 62.5%

minowa: Methylmalonyl-CoA

Prediction, score:

Methylmalonyl-CoA: 90.0
Methoxymalonyl-CoA: 72.7
Propionyl-CoA: 58.5
Isobutyryl-CoA: 48.5
Malonyl-CoA: 45.8
Ethylmalonyl-CoA: 45.1
Benzoyl-CoA: 30.0
fatty_acid: 28.9
trans-1,2-CPDA: 28.7
2-Methylbutyryl-CoA: 25.0
CHC-CoA: 23.0
3-Methylbutyryl-CoA: 19.6
inactive: 8.6
Acetyl-CoA: 0.0

scaffold_201 - Region 1 - terpene

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Location: 1 - 16,401 nt. (total: 16,401 nt) Show pHMM detection rules used

Region on contig edge.

terpene: (Terpene_synth or Terpene_synth_C or phytoene_synt or Lycopene_cycl or terpene_cyclase or NapT7 or fung_ggpps or fung_ggpps2 or trichodiene_synth or TRI5)

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scaffold_20175 - Region 1 - NRPS-like

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Location: 6,301 - 50,005 nt. (total: 43,705 nt) Show pHMM detection rules used

Region on contig edge.

NRPS-like: cds((PP-binding or NAD_binding_4) and (AMP-binding or A-OX))

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Predicted core structure(s)

For candidate cluster 1, location 6300 - 50005:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (X)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

121086

AMP-binding (109..385): X

nrpys: Asp, Asn, Glu, Gln, Aad

SVM prediction details:

Predicted physicochemical class:: hydrophilic (Arg, Asp, Glu, Asn, Lys, Gln, Orn, Aad)
Large clusters prediction:: Aliphatic chain with H-bond donor (Asp, Asn, Glu, Gln, Aad)
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: HGASGGRFLK
Nearest Stachelhaus code(s):
Stachelhaus code match:: 0% (weak)

scaffold_23089 - Region 1 - T1PKS

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Location: 1 - 41,185 nt. (total: 41,185 nt) Show pHMM detection rules used

Region on contig edge.

T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))

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Predicted core structure(s)

For candidate cluster 1, location 0 - 41185:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (mal)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

121716

PKS_AT (854..1123): mal

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 75.0%; inactive: 66.7%; Methylmalonyl-CoA: 54.2%

minowa: Malonyl-CoA

Prediction, score:

Malonyl-CoA: 103.9
inactive: 66.5
Methoxymalonyl-CoA: 56.7
Methylmalonyl-CoA: 52.0
Ethylmalonyl-CoA: 26.1
Isobutyryl-CoA: 24.5
Benzoyl-CoA: 22.8
2-Methylbutyryl-CoA: 14.5
Acetyl-CoA: 13.2
CHC-CoA: 12.8
Propionyl-CoA: 12.2
fatty_acid: 11.2
3-Methylbutyryl-CoA: 10.5
trans-1,2-CPDA: 7.8

scaffold_23875 - Region 1 - fungal-RiPP-like

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Location: 1 - 65,792 nt. (total: 65,792 nt) Show pHMM detection rules used

Region on contig edge.

fungal-RiPP-like: DUF3328

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scaffold_257 - Region 1 - T1PKS

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Location: 1 - 65,723 nt. (total: 65,723 nt) Show pHMM detection rules used

Region on contig edge.

T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))

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Predicted core structure(s)

For candidate cluster 1, location 0 - 65723:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (pk)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

122175

PKS_AT (547..868): pk

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 87.5%; Methylmalonyl-CoA: 75.0%; Ethylmalonyl-CoA: 62.5%

minowa: Methoxymalonyl-CoA

Prediction, score:

Methoxymalonyl-CoA: 87.7
Methylmalonyl-CoA: 85.4
Malonyl-CoA: 67.2
Isobutyryl-CoA: 56.3
Benzoyl-CoA: 49.3
inactive: 41.8
Ethylmalonyl-CoA: 40.7
Propionyl-CoA: 37.6
2-Methylbutyryl-CoA: 31.1
3-Methylbutyryl-CoA: 31.0
CHC-CoA: 26.2
trans-1,2-CPDA: 19.6
fatty_acid: 15.6
Acetyl-CoA: 6.2

scaffold_25848 - Region 1 - T1PKS

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Location: 21,870 - 90,246 nt. (total: 68,377 nt) Show pHMM detection rules used

T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))

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NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 1, location 21869 - 90246:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (redmal)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

122255

PKS_AT (625..952): mal

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 70.8%; Methylmalonyl-CoA: 66.7%; Methoxymalonyl-CoA: 54.2%

minowa: Malonyl-CoA

Prediction, score:

Malonyl-CoA: 75.9
Methylmalonyl-CoA: 72.3
Methoxymalonyl-CoA: 65.7
Isobutyryl-CoA: 63.3
inactive: 32.5
Ethylmalonyl-CoA: 32.3
Propionyl-CoA: 31.5
Benzoyl-CoA: 24.4
fatty_acid: 21.8
3-Methylbutyryl-CoA: 18.5
CHC-CoA: 16.8
trans-1,2-CPDA: 16.0
2-Methylbutyryl-CoA: 15.7
Acetyl-CoA: 13.2

scaffold_269 - Region 1 - T1PKS

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Location: 1 - 48,359 nt. (total: 48,359 nt) Show pHMM detection rules used

Region on contig edge.

T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))

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Predicted core structure(s)

For candidate cluster 1, location 0 - 48359:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (mal)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

122274

PKS_AT (911..1228): mal

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 87.5%; inactive: 58.3%; Methylmalonyl-CoA: 54.2%

minowa: Malonyl-CoA

Prediction, score:

Malonyl-CoA: 108.7
inactive: 56.0
Methylmalonyl-CoA: 48.2
Methoxymalonyl-CoA: 48.1
Propionyl-CoA: 20.0
fatty_acid: 17.6
2-Methylbutyryl-CoA: 16.5
Benzoyl-CoA: 16.0
Ethylmalonyl-CoA: 13.2
Acetyl-CoA: 12.8
CHC-CoA: 11.1
Isobutyryl-CoA: 8.2
3-Methylbutyryl-CoA: 6.3
trans-1,2-CPDA: 0.0

scaffold_2928 - Region 1 - fungal-RiPP-like

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Location: 1 - 25,783 nt. (total: 25,783 nt) Show pHMM detection rules used

Region on contig edge.

fungal-RiPP-like: DUF3328

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scaffold_2955 - Region 1 - NRPS

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Location: 1 - 26,381 nt. (total: 26,381 nt) Show pHMM detection rules used

Region on contig edge.

NRPS: cds(Condensation and (AMP-binding or A-OX))

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Predicted core structure(s)

For candidate cluster 1, location 0 - 26381:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (X - X)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

122579

AMP-binding (13..409): X

nrpys: Ala, Gly, Val, Leu, Ile, Abu, Ival, Ser, Thr, Hpg, Dhpg, Cys, Pro, Hpr

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic (Ala, Gly, Val, Leu, Ile, Abu, Ival, Ser, Thr, Hpg, Dhpg, Cys, Pro, Hpr)
Large clusters prediction:: N/A
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: DAAVIGAIMK
Nearest Stachelhaus code(s):: Leu DAWIIGAIVK (41% 8� match)
Stachelhaus code match:: 70% (weak)

AMP-binding (1081..1442): X

nrpys: Ala, Gly, Val, Leu, Ile, Abu, Ival, Ser, Thr, Hpg, Dhpg, Cys, Pro, Hpr

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic (Ala, Gly, Val, Leu, Ile, Abu, Ival, Ser, Thr, Hpg, Dhpg, Cys, Pro, Hpr)
Large clusters prediction:: N/A
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: DILIVGGSIK
Nearest Stachelhaus code(s):: Ala DLGIVGGMIK (59% 8� match)
Stachelhaus code match:: 70% (weak)

scaffold_3086 - Region 1 - terpene

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Location: 31,277 - 70,348 nt. (total: 39,072 nt) Show pHMM detection rules used

Region on contig edge.

terpene: (Terpene_synth or Terpene_synth_C or phytoene_synt or Lycopene_cycl or terpene_cyclase or NapT7 or fung_ggpps or fung_ggpps2 or trichodiene_synth or TRI5)

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scaffold_3113 - Region 1 - fungal-RiPP-like

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Location: 26,799 - 102,334 nt. (total: 75,536 nt) Show pHMM detection rules used

Region on contig edge.

fungal-RiPP-like: DUF3328

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scaffold_3213 - Region 1 - terpene

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Location: 1 - 29,042 nt. (total: 29,042 nt) Show pHMM detection rules used

Region on contig edge.

terpene: (Terpene_synth or Terpene_synth_C or phytoene_synt or Lycopene_cycl or terpene_cyclase or NapT7 or fung_ggpps or fung_ggpps2 or trichodiene_synth or TRI5)

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scaffold_3284 - Region 1 - T1PKS

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Location: 1 - 33,561 nt. (total: 33,561 nt) Show pHMM detection rules used

Region on contig edge.

T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))

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Predicted core structure(s)

For candidate cluster 1, location 0 - 33561:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (mal)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

123122

PKS_AT (893..1201): mal

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 70.8%; inactive: 62.5%; Methylmalonyl-CoA: 54.2%

minowa: inactive

Prediction, score:

inactive: 68.3
Methoxymalonyl-CoA: 48.3
Methylmalonyl-CoA: 38.9
Isobutyryl-CoA: 21.0
Benzoyl-CoA: 12.3
Propionyl-CoA: 11.9
Ethylmalonyl-CoA: 2.7
trans-1,2-CPDA: 0.0
fatty_acid: 0.0
CHC-CoA: 0.0
Acetyl-CoA: 0.0
3-Methylbutyryl-CoA: 0.0
2-Methylbutyryl-CoA: 0.0
Malonyl-CoA: -3.1

scaffold_3547 - Region 1 - fungal-RiPP-like

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Location: 45,537 - 136,095 nt. (total: 90,559 nt) Show pHMM detection rules used

fungal-RiPP-like: DUF3328

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scaffold_4465 - Region 1 - terpene

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Location: 1 - 23,907 nt. (total: 23,907 nt) Show pHMM detection rules used

Region on contig edge.

terpene: (Terpene_synth or Terpene_synth_C or phytoene_synt or Lycopene_cycl or terpene_cyclase or NapT7 or fung_ggpps or fung_ggpps2 or trichodiene_synth or TRI5)

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scaffold_4700 - Region 1 - T1PKS

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Location: 1 - 62,059 nt. (total: 62,059 nt) Show pHMM detection rules used

Region on contig edge.

T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))

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Predicted core structure(s)

For candidate cluster 1, location 0 - 62059:

Rough prediction of core scaffold based on assumed PKS linker matching; tailoring reactions not taken into account

Polymer prediction:: (pk) + (mal)
Non-colinear ordering:: 124121 + 124124

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

124121

PKS_AT (484..800): pk

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 79.2%; Methylmalonyl-CoA: 66.7%; Ethylmalonyl-CoA: 58.3%

minowa: Methylmalonyl-CoA

Prediction, score:

Methylmalonyl-CoA: 87.2
Methoxymalonyl-CoA: 77.9
Ethylmalonyl-CoA: 67.9
Malonyl-CoA: 59.2
Isobutyryl-CoA: 52.3
2-Methylbutyryl-CoA: 37.3
Propionyl-CoA: 34.1
Benzoyl-CoA: 30.0
trans-1,2-CPDA: 25.1
CHC-CoA: 24.8
fatty_acid: 19.3
inactive: 13.8
Acetyl-CoA: 12.6
3-Methylbutyryl-CoA: 12.5

124124

PKS_AT (908..1212): mal

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 75.0%; Methylmalonyl-CoA: 54.2%; inactive: 54.2%

minowa: Malonyl-CoA

Prediction, score:

Malonyl-CoA: 94.7
Methoxymalonyl-CoA: 51.1
Methylmalonyl-CoA: 42.0
inactive: 36.5
Isobutyryl-CoA: 26.2
Benzoyl-CoA: 15.4
Propionyl-CoA: 14.8
fatty_acid: 11.3
2-Methylbutyryl-CoA: 8.8
trans-1,2-CPDA: 0.0
Ethylmalonyl-CoA: 0.0
CHC-CoA: 0.0
Acetyl-CoA: 0.0
3-Methylbutyryl-CoA: 0.0

scaffold_4873 - Region 1 - fungal-RiPP-like

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Location: 1 - 17,005 nt. (total: 17,005 nt) Show pHMM detection rules used

Region on contig edge.

fungal-RiPP-like: DUF3328

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scaffold_5370 - Region 1 - NRPS

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Location: 1 - 50,448 nt. (total: 50,448 nt) Show pHMM detection rules used

Region on contig edge.

NRPS: cds(Condensation and (AMP-binding or A-OX))

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Predicted core structure(s)

For candidate cluster 1, location 0 - 50448:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (X - X)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

124752

AMP-binding (295..672): X

nrpys: Asp, Asn, Glu, Gln, Aad

SVM prediction details:

Predicted physicochemical class:: hydrophilic (Arg, Asp, Glu, Asn, Lys, Gln, Orn, Aad)
Large clusters prediction:: Aliphatic chain with H-bond donor (Asp, Asn, Glu, Gln, Aad)
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: SARETGAQMK
Nearest Stachelhaus code(s):
Stachelhaus code match:: 0% (weak)

AMP-binding (1239..1613): X

nrpys: Ala, Gly, Val, Leu, Ile, Abu, Ival, Ser, Thr, Hpg, Dhpg, Cys, Pro, Hpr

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic (Ala, Gly, Val, Leu, Ile, Abu, Ival, Ser, Thr, Hpg, Dhpg, Cys, Pro, Hpr)
Large clusters prediction:: N/A
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: DAYMNCGILK
Nearest Stachelhaus code(s):: Val DAWMFAAILK (50% 8� match)
Stachelhaus code match:: 60% (weak)

scaffold_541 - Region 1 - T1PKS

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Location: 1 - 58,630 nt. (total: 58,630 nt) Show pHMM detection rules used

Region on contig edge.

T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))

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Predicted core structure(s)

For candidate cluster 1, location 0 - 58630:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (pk)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

124785

PKS_AT (590..872): pk

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 62.5%; Methylmalonyl-CoA: 54.2%

minowa: Methylmalonyl-CoA

Prediction, score:

Methylmalonyl-CoA: 68.0
Methoxymalonyl-CoA: 51.2
Ethylmalonyl-CoA: 45.0
Malonyl-CoA: 28.4
fatty_acid: 23.0
Propionyl-CoA: 22.4
Benzoyl-CoA: 19.8
2-Methylbutyryl-CoA: 14.5
Isobutyryl-CoA: 9.9
CHC-CoA: 9.8
trans-1,2-CPDA: 0.0
inactive: 0.0
Acetyl-CoA: 0.0
3-Methylbutyryl-CoA: 0.0

scaffold_5626 - Region 1 - NRPS,T1PKS

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Location: 1 - 47,396 nt. (total: 47,396 nt) Show pHMM detection rules used

Region on contig edge.

NRPS: cds(Condensation and (AMP-binding or A-OX))
T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))

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Predicted core structure(s)

For candidate cluster 1, location 0 - 47396:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (pk - X)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

124941

PKS_AT (575..875): pk

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 75.0%; Methylmalonyl-CoA: 62.5%; Ethylmalonyl-CoA: 54.2%

minowa: Methylmalonyl-CoA

Prediction, score:

Methylmalonyl-CoA: 61.8
Methoxymalonyl-CoA: 51.8
Ethylmalonyl-CoA: 49.9
Malonyl-CoA: 30.5
trans-1,2-CPDA: 22.5
Benzoyl-CoA: 21.4
Propionyl-CoA: 20.1
fatty_acid: 20.0
Isobutyryl-CoA: 17.9
2-Methylbutyryl-CoA: 13.5
inactive: 13.3
CHC-CoA: 0.0
Acetyl-CoA: 0.0
3-Methylbutyryl-CoA: 0.0

AMP-binding (3013..3423): X

nrpys: Orn, Lys, Arg

SVM prediction details:

Predicted physicochemical class:: hydrophilic (Arg, Asp, Glu, Asn, Lys, Gln, Orn, Aad)
Large clusters prediction:: Long positively charged side chain (Orn, Lys, Arg)
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: DFDKFGSIAK
Nearest Stachelhaus code(s):: Phe NHDKFGSISK (79% 8� match); MalAc NHDKFGSISK (76% 8� match); Ser DFDTFGGILK (59% 8� match); Tyr DFESFGNIAK (53% 8� match)
Stachelhaus code match:: 70% (weak)

scaffold_6978 - Region 1 - T1PKS

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Location: 90,803 - 139,919 nt. (total: 49,117 nt) Show pHMM detection rules used

Region on contig edge.

T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))

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Predicted core structure(s)

For candidate cluster 1, location 90802 - 139919:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (pk)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

125579

PKS_AT (343..664): pk

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 79.2%; Methylmalonyl-CoA: 66.7%; Ethylmalonyl-CoA: 58.3%

minowa: Methylmalonyl-CoA

Prediction, score:

Methylmalonyl-CoA: 79.8
Methoxymalonyl-CoA: 74.6
Ethylmalonyl-CoA: 58.4
Isobutyryl-CoA: 42.9
Malonyl-CoA: 30.5
Propionyl-CoA: 28.9
Benzoyl-CoA: 24.6
fatty_acid: 20.1
2-Methylbutyryl-CoA: 19.2
trans-1,2-CPDA: 18.1
CHC-CoA: 11.3
3-Methylbutyryl-CoA: 10.9
inactive: 0.0
Acetyl-CoA: 0.0

scaffold_7007 - Region 1 - NRPS,T1PKS

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Location: 1 - 37,359 nt. (total: 37,359 nt) Show pHMM detection rules used

Region on contig edge.

NRPS: cds(Condensation and (AMP-binding or A-OX))
T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))

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NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 1, location 0 - 37359:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (pk) + (X)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

125591

PKS_AT (628..894): pk

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 70.8%; 2-Rhyd-Malonyl-CoA: 54.2%; Methylmalonyl-CoA: 54.2%

minowa: Methylmalonyl-CoA

Prediction, score:

Methylmalonyl-CoA: 62.1
Methoxymalonyl-CoA: 53.8
Malonyl-CoA: 29.8
Isobutyryl-CoA: 29.4
Propionyl-CoA: 28.4
Ethylmalonyl-CoA: 27.6
fatty_acid: 20.6
trans-1,2-CPDA: 18.8
Benzoyl-CoA: 15.2
2-Methylbutyryl-CoA: 13.1
CHC-CoA: 12.0
inactive: 0.0
Acetyl-CoA: 0.0
3-Methylbutyryl-CoA: 0.0

125596

AMP-binding (17..402): X

nrpys: Ala, Gly, Val, Leu, Ile, Abu, Ival, Ser, Thr, Hpg, Dhpg, Cys, Pro, Hpr

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic (Ala, Gly, Val, Leu, Ile, Abu, Ival, Ser, Thr, Hpg, Dhpg, Cys, Pro, Hpr)
Large clusters prediction:: N/A
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: DGGHFGTCIK
Nearest Stachelhaus code(s):: Trp DVGPFGACTK (56% 8� match)
Stachelhaus code match:: 60% (weak)

scaffold_7455 - Region 1 - NRPS-like,T1PKS

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Location: 24,291 - 92,765 nt. (total: 68,475 nt) Show pHMM detection rules used

Region on contig edge.

T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))
NRPS-like: cds((PP-binding or NAD_binding_4) and (AMP-binding or A-OX))

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NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 1, location 24290 - 92765:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (X - pk)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

125920

AMP-binding (104..379): X

nrpys: Ala, Gly, Val, Leu, Ile, Abu, Ival, Ser, Thr, Hpg, Dhpg, Cys, Pro, Hpr

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic (Ala, Gly, Val, Leu, Ile, Abu, Ival, Ser, Thr, Hpg, Dhpg, Cys, Pro, Hpr)
Large clusters prediction:: N/A
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: GFLMAGSPLK
Nearest Stachelhaus code(s):
Stachelhaus code match:: 0% (weak)

PKS_AT (1963..2270): pk

ATSignature: (unknown)

No matches above 50%

minowa: inactive

Prediction, score:

inactive: 52.9
Malonyl-CoA: 52.4
Methoxymalonyl-CoA: 39.5
Methylmalonyl-CoA: 24.2
Ethylmalonyl-CoA: 15.4
fatty_acid: 15.1
Propionyl-CoA: 13.3
CHC-CoA: 12.3
Benzoyl-CoA: 10.6
2-Methylbutyryl-CoA: 10.1
trans-1,2-CPDA: 0.0
Isobutyryl-CoA: 0.0
Acetyl-CoA: 0.0
3-Methylbutyryl-CoA: 0.0

scaffold_7474 - Region 1 - NRPS-like,T1PKS

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Location: 1 - 45,100 nt. (total: 45,100 nt) Show pHMM detection rules used

Region on contig edge.

NRPS-like: cds((PP-binding or NAD_binding_4) and (AMP-binding or A-OX))
T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))

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Predicted core structure(s)

For candidate cluster 1, location 0 - 45100:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (pk)

Direct lookup in NORINE database: strict or relaxed

For candidate cluster 3, location 7586 - 45100:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (pk)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

125948

PKS_AT (339..622): pk

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 58.3%

minowa: Methoxymalonyl-CoA

Prediction, score:

Methoxymalonyl-CoA: 48.6
inactive: 42.7
Methylmalonyl-CoA: 41.5
Malonyl-CoA: 30.5
Isobutyryl-CoA: 19.7
Ethylmalonyl-CoA: 16.2
2-Methylbutyryl-CoA: 15.9
Propionyl-CoA: 13.1
Benzoyl-CoA: 13.1
CHC-CoA: 11.6
Acetyl-CoA: 11.5
3-Methylbutyryl-CoA: 10.3
fatty_acid: 9.5
trans-1,2-CPDA: 0.0

scaffold_7545 - Region 1 - terpene

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Location: 40,504 - 75,102 nt. (total: 34,599 nt) Show pHMM detection rules used

Region on contig edge.

terpene: (Terpene_synth or Terpene_synth_C or phytoene_synt or Lycopene_cycl or terpene_cyclase or NapT7 or fung_ggpps or fung_ggpps2 or trichodiene_synth or TRI5)

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scaffold_8394 - Region 1 - NRPS,T1PKS,transAT-PKS

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Location: 73,840 - 180,708 nt. (total: 106,869 nt) Show pHMM detection rules used

Region on contig edge.

NRPS: cds(Condensation and (AMP-binding or A-OX))
transAT-PKS: (cds(PKS_AT and not (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS)) and (cds(ATd and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS)) or cds(tra_KS and PP-binding)))
T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))

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NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 1, location 73839 - 180708:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (X - Ala) + (mal)

Direct lookup in NORINE database: strict or relaxed

For candidate cluster 2, location 73839 - 139356:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (X - Ala)

Direct lookup in NORINE database: strict or relaxed

For candidate cluster 3, location 113010 - 180708:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (mal)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

126461

Search NORINE for peptide: strict or relaxed

AMP-binding (46..436): X

nrpys: Ile, Leu, Val

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic (Ala, Gly, Val, Leu, Ile, Abu, Ival, Ser, Thr, Hpg, Dhpg, Cys, Pro, Hpr)
Large clusters prediction:: Apolar, aliphatic (Gly, Ala, Val, Leu, Ile, Abu, Ival)
Small clusters prediction:: Aliphatic, branched hydrophobic (Val, Leu, Ile, Abu, Ival)
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: DALFIGGVIK
Nearest Stachelhaus code(s):: Ile DALFMGGVYK (65% 8� match); Val DALFIGGTFK (50% 8� match); Leu or Ile DALFIGGTFK (47% 8� match)
Stachelhaus code match:: 80% (moderate)

AMP-binding (1136..1550): Ala

nrpys: Ala

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic (Ala, Gly, Val, Leu, Ile, Abu, Ival, Ser, Thr, Hpg, Dhpg, Cys, Pro, Hpr)
Large clusters prediction:: Apolar, aliphatic (Gly, Ala, Val, Leu, Ile, Abu, Ival)
Small clusters prediction:: Tiny, hydrophilic, transition to aliphatic (Gly, Ala)
Single AA prediction:: ala (Ala)

Stachelhaus prediction details:

Stachelhaus sequence:: DISCVAMIYK
Nearest Stachelhaus code(s):: Aol DIWFVAGIYK (50% 8� match)
Stachelhaus code match:: 70% (weak)

126473

PKS_AT (3..321): pk

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 79.2%; Methylmalonyl-CoA: 66.7%; Isobutyryl-CoA: 58.3%

minowa: Methoxymalonyl-CoA

Prediction, score:

Methoxymalonyl-CoA: 94.1
Methylmalonyl-CoA: 92.9
Malonyl-CoA: 78.7
Isobutyryl-CoA: 63.5
Ethylmalonyl-CoA: 52.4
2-Methylbutyryl-CoA: 50.3
Propionyl-CoA: 46.5
inactive: 38.4
trans-1,2-CPDA: 36.5
Benzoyl-CoA: 30.3
3-Methylbutyryl-CoA: 18.0
fatty_acid: 13.0
CHC-CoA: 12.8
Acetyl-CoA: 0.0

126476

PKS_AT (773..1082): mal

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 58.3%

minowa: inactive

Prediction, score:

inactive: 36.3
Methylmalonyl-CoA: 24.0
Methoxymalonyl-CoA: 21.2
Isobutyryl-CoA: 16.2
Benzoyl-CoA: 13.5
Malonyl-CoA: 7.1
trans-1,2-CPDA: 0.0
fatty_acid: 0.0
Propionyl-CoA: 0.0
Ethylmalonyl-CoA: 0.0
CHC-CoA: 0.0
Acetyl-CoA: 0.0
3-Methylbutyryl-CoA: 0.0
2-Methylbutyryl-CoA: 0.0

scaffold_8592 - Region 1 - indole

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Location: 1 - 24,716 nt. (total: 24,716 nt) Show pHMM detection rules used

Region on contig edge.

indole: (indsynth or dmat or indole_PTase)

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No matches found.

scaffold_8699 - Region 1 - T1PKS

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Location: 1 - 72,513 nt. (total: 72,513 nt) Show pHMM detection rules used

Region on contig edge.

T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))

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NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 1, location 0 - 72513:

Rough prediction of core scaffold based on assumed PKS linker matching; tailoring reactions not taken into account

Polymer prediction:: (pk) + (mal)
Non-colinear ordering:: 126803 + 126808

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

126803

PKS_AT (592..903): pk

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 66.7%; Methylmalonyl-CoA: 54.2%

minowa: Methylmalonyl-CoA

Prediction, score:

Methylmalonyl-CoA: 59.2
Malonyl-CoA: 58.5
Methoxymalonyl-CoA: 54.9
Isobutyryl-CoA: 34.7
Benzoyl-CoA: 23.3
Ethylmalonyl-CoA: 20.3
Propionyl-CoA: 14.2
fatty_acid: 12.2
trans-1,2-CPDA: 11.1
CHC-CoA: 11.1
2-Methylbutyryl-CoA: 5.3
inactive: 0.0
Acetyl-CoA: 0.0
3-Methylbutyryl-CoA: 0.0

126808

PKS_AT (917..1212): mal

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 58.3%

minowa: Malonyl-CoA

Prediction, score:

Malonyl-CoA: 56.7
inactive: 55.4
Methoxymalonyl-CoA: 49.2
Methylmalonyl-CoA: 36.0
Propionyl-CoA: 17.9
CHC-CoA: 16.6
Ethylmalonyl-CoA: 14.0
3-Methylbutyryl-CoA: 13.9
Isobutyryl-CoA: 11.5
trans-1,2-CPDA: 11.1
fatty_acid: 10.6
Benzoyl-CoA: 10.1
2-Methylbutyryl-CoA: 10.1
Acetyl-CoA: 0.0

scaffold_8982 - Region 1 - NRPS,indole

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Location: 33,412 - 97,968 nt. (total: 64,557 nt) Show pHMM detection rules used

NRPS: cds(Condensation and (AMP-binding or A-OX))
indole: (indsynth or dmat or indole_PTase)

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NRPS/PKS monomer predictions

127119

AMP-binding (430..811): X

nrpys: (unknown)

SVM prediction details:

Predicted physicochemical class:: N/A
Large clusters prediction:: N/A
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: DAAMFGAVGK
Nearest Stachelhaus code(s):: Tyr DAIDVGAVGK (50% 8� match); Leu DAWMYGAVIK (47% 8� match)
Stachelhaus code match:: 70% (weak)

127120

AMP-binding (15..214): X